The Use of the Perfusion Index to Predict Post-Induction Hypotension in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Protocol
2.2. Data Source and Literature Search
2.3. Inclusion and Exclusion Criteria
2.4. Data Extraction
2.5. Outcomes and Definitions
2.6. Quality Assessment
2.7. Statistical Analysis
3. Results
3.1. Study Selection and Study Characteristics
3.2. Outcomes
3.2.1. Pooled Incidence of Post-Induction Hypotension
3.2.2. Pooled Sensitivity, Specificity, and Area under Curve
3.2.3. Fagan’s Nomogram Analysis
3.2.4. Deek’s Funnel Plot Asymmetry Test
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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1 | (“General anesthesia” or “Inhalation agents” or “Propofol” or “Total intravenous anesthesia” or “Tracheal intubation” or “Sevoflurane” or “Isoflurane” or “desflurane”).mp. |
2 | exp “Anesthetics, General”/ |
3 | (“Perfusion index” or “PI” or “Peripheral perfusion index”).mp. |
4 | exp “Perfusion Index”/ |
5 | (“Hypotension” or “Low Blood Pressure” or “Reduced blood pressure”).mp. |
6 | exp “Hypotension”/ |
7 | (1 or 2) and (3 or 4) and (5 or 6) |
Studies | Age (Years) | Sex (M/F) | N | ASA | PI Cut-Off Value | AUC | Country |
---|---|---|---|---|---|---|---|
Abdelhamid 2022 [20] | 31 | 49/44 | 93 | I-II | <3.03 | 0.776 | Egypt |
Abdullah Mohamed 2023 [17] | 71 | 19/11 | 30 | I-II | ≤1.3 | 0.97 | Egypt |
Gunashekar 2024 [23] | 40 | 83/57 | 140 | I-II | <3.5 | 0.647 | India |
Mehandale 2017 [24] | 31 | 29/21 | 50 | I-II | <1.05 | 0.816 | India |
Min 2022 [25] | 66–68 | 17/13 | 30 | II | ≤0.96 | 1 | Korea |
Rajeev 2024 [18] | 39 | 60/114 | 174 | I-II | <2.45 | 0.8793 | India |
Soni 2023 [19] | 40 | 27/28 | 55 | I-II | <1.03 | 0.913 | India |
Thirunelli 2021 [21] | 42 | 53/53 | 106 | I-II | <1.05 | 0.511 | India |
Studies | Induction Agent (Propofol) | PIH (%) | Definition of Hypotension | Follow-Up |
---|---|---|---|---|
Abdelhamid 2022 [20] | 1.5–2 mg/kg | 48.40% | dMAP > 25% baseline | na # |
Abdullah Mohamed 2023 [17] | 1–2 mg/kg | 53.30% | dSBP of >30% of baseline | 3 min |
Gunashekar 2024 [23] | 2 mg/kg | 45% | dSBP of >30% of baseline | 5 min |
Mehandale 2017 [24] | 10 mg per every 5 s † | 30% | dSBP of >30% of baseline or MAP < 60 mmHg | 5 min |
Min 2022 [25] | 3.0 μg/mL ⁋ | 66.70% | SBP < 90 mmHg | 15 min |
Rajeev 2024 [18] | 10 mg per every 5 s † | 17.20% | MAP < 60 mmHg | 5 min |
Soni 2023 [19] | 10 mg per every 5 s † | 29% | dSBP > 30% of baseline or MAP < 60 mmHg | 5 min |
Thirunelli 2021 [21] | 2 mg/kg | 76.40% | dMAP > 20% of baseline or MAP < 60 mmHg | 5 min |
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Hung, K.-C.; Liao, S.-W.; Kao, C.-L.; Huang, Y.-T.; Wu, J.-Y.; Lin, Y.-T.; Lin, C.-M.; Lin, C.-H.; Chen, I.-W. The Use of the Perfusion Index to Predict Post-Induction Hypotension in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis. Diagnostics 2024, 14, 1769. https://doi.org/10.3390/diagnostics14161769
Hung K-C, Liao S-W, Kao C-L, Huang Y-T, Wu J-Y, Lin Y-T, Lin C-M, Lin C-H, Chen I-W. The Use of the Perfusion Index to Predict Post-Induction Hypotension in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis. Diagnostics. 2024; 14(16):1769. https://doi.org/10.3390/diagnostics14161769
Chicago/Turabian StyleHung, Kuo-Chuan, Shu-Wei Liao, Chia-Li Kao, Yen-Ta Huang, Jheng-Yan Wu, Yao-Tsung Lin, Chien-Ming Lin, Chien-Hung Lin, and I-Wen Chen. 2024. "The Use of the Perfusion Index to Predict Post-Induction Hypotension in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis" Diagnostics 14, no. 16: 1769. https://doi.org/10.3390/diagnostics14161769
APA StyleHung, K. -C., Liao, S. -W., Kao, C. -L., Huang, Y. -T., Wu, J. -Y., Lin, Y. -T., Lin, C. -M., Lin, C. -H., & Chen, I. -W. (2024). The Use of the Perfusion Index to Predict Post-Induction Hypotension in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis. Diagnostics, 14(16), 1769. https://doi.org/10.3390/diagnostics14161769