Previous Article in Journal
Telomere Length and Genetic Variations in Acquired Pediatric Aplastic Anemia: A Flow-FISH Study in Korean Patients
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Diagnostics
Volume 15
Issue 7
10.3390/diagnostics15070932
diagnostics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Review

Endoscopic Full Thickness Resection Device (FTRD®) for the Management of Gastrointestinal Lesions: Current Evidence and Future Perspectives

by
Μagdalini Μanti
1,
Apostolis Papaefthymiou
2,
Spyridon Dritsas
3,
Nikolaos Kamperidis
1,
Ioannis S. Papanikolaou
4,
Konstantina Paraskeva
5,
Antonio Facciorusso
6,
Konstantinos Triantafyllou
4,
Vasilios Papadopoulos
2,
Georgios Tziatzios
5 and
Paraskevas Gkolfakis
4,*
1
Gastroenterology Unit, St Mark’s Hospital, Acton Ln, London NW10 7NS, UK
2
Department of Gastroenterology, General University Hospital of Larissa, 41334 Larissa, Greece
3
1st Surgical Department and Transplant Unit, Evaggelismos General Hospital, 10676 Athens, Greece
4
Hepatogastroenterology Unit, Second Department of Internal Medicine-Propaedeutic, Attikon University Hospital, Rimini 1, Chaidari, 12462 Athens, Greece
5
Department of Gastroenterology, “Konstantopoulio-Patision” General Hospital of Nea Ionia, 14233 Athens, Greece
6
Gastroenterology Unit, Department of Surgical and Medical Sciences, University of Foggia, 71122 Foggia, Italy
*
Author to whom correspondence should be addressed.
Diagnostics 2025, 15(7), 932; https://doi.org/10.3390/diagnostics15070932 (registering DOI)
Submission received: 26 February 2025 / Revised: 27 March 2025 / Accepted: 28 March 2025 / Published: 4 April 2025
(This article belongs to the Special Issue Diagnosis and Prognosis of Abdominal Diseases)
Versions Notes

Abstract

Endoscopic full-thickness resection (EFTR) has emerged as a transformative technique for managing gastrointestinal (GI) lesions, previously deemed unsuitable for endoscopic removal. Unlike conventional endoscopic resection methods, such as endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), EFTR enables en bloc excision of both intraluminal and subepithelial lesions by resecting all layers of the GI wall, followed by defect closure to prevent complications. The introduction of the full-thickness resection device (FTRD®) has significantly enhanced the feasibility and safety of EFTR, particularly in the colon and upper GI tract, with increasing adoption worldwide. This review provides a comprehensive analysis of FTRD®, focusing on its clinical applications, procedural methodology, and comparative efficacy against other endoscopic resection techniques. The indications and contraindications for EFTR are explored, highlighting its utility in treating non-lifting adenomas, subepithelial tumours, and T1 carcinomas without lymph node involvement. This review synthesizes current clinical data and FTRD® advantages. Despite its strengths, EFTR via FTRD® incorporates challenges such as limitations in lesion size, procedural complexity, and potential adverse events. Strategies for overcoming these challenges, including hybrid techniques and modifications in procedural approach, are examined. The review also emphasizes the need for further research to optimize surveillance strategies and determine the long-term clinical impact of EFTR in GI lesion management. By integrating recent evidence, this paper provides valuable insights into the evolving role of EFTR in therapeutic endoscopy.
Keywords: full thickness resection device; FTRD®, EFTR; gastrointestinal lesions; endoscopic resection full thickness resection device; FTRD®, EFTR; gastrointestinal lesions; endoscopic resection

Share and Cite

MDPI and ACS Style

Μanti, Μ.; Papaefthymiou, A.; Dritsas, S.; Kamperidis, N.; Papanikolaou, I.S.; Paraskeva, K.; Facciorusso, A.; Triantafyllou, K.; Papadopoulos, V.; Tziatzios, G.; et al. Endoscopic Full Thickness Resection Device (FTRD®) for the Management of Gastrointestinal Lesions: Current Evidence and Future Perspectives. Diagnostics 2025, 15, 932. https://doi.org/10.3390/diagnostics15070932

AMA Style

Μanti Μ, Papaefthymiou A, Dritsas S, Kamperidis N, Papanikolaou IS, Paraskeva K, Facciorusso A, Triantafyllou K, Papadopoulos V, Tziatzios G, et al. Endoscopic Full Thickness Resection Device (FTRD®) for the Management of Gastrointestinal Lesions: Current Evidence and Future Perspectives. Diagnostics. 2025; 15(7):932. https://doi.org/10.3390/diagnostics15070932

Chicago/Turabian Style

Μanti, Μagdalini, Apostolis Papaefthymiou, Spyridon Dritsas, Nikolaos Kamperidis, Ioannis S. Papanikolaou, Konstantina Paraskeva, Antonio Facciorusso, Konstantinos Triantafyllou, Vasilios Papadopoulos, Georgios Tziatzios, and et al. 2025. "Endoscopic Full Thickness Resection Device (FTRD®) for the Management of Gastrointestinal Lesions: Current Evidence and Future Perspectives" Diagnostics 15, no. 7: 932. https://doi.org/10.3390/diagnostics15070932

APA Style

Μanti, Μ., Papaefthymiou, A., Dritsas, S., Kamperidis, N., Papanikolaou, I. S., Paraskeva, K., Facciorusso, A., Triantafyllou, K., Papadopoulos, V., Tziatzios, G., & Gkolfakis, P. (2025). Endoscopic Full Thickness Resection Device (FTRD®) for the Management of Gastrointestinal Lesions: Current Evidence and Future Perspectives. Diagnostics, 15(7), 932. https://doi.org/10.3390/diagnostics15070932

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop