Triple Test Plus Rapid Cognitive Screening Test: A Combination of Clinical Signs and A Tool for Cognitive Assessment in Older Adults
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Control (n = 237) | MCI (n = 59) | AD (n = 61) | P1 | P2 | P3 | |
---|---|---|---|---|---|---|
Women (%) | 66.2 | 51.7 | 53.3 | 0.041 | - | - |
Age | 72.45 ± 7.08 | 76.37 ± 6.09 | 78.95 ± 7.63 | <0.001 | - | - |
Education (year) | 8.61 ± 3.84 | 7.98 ± 3.76 | 8.48 ± 4.09 | 0.390 | - | - |
Number of drugs | 5.33 ± 3.33 | 5.65 ± 3.02 | 5.92 ± 3.07 | 0.214 | - | - |
MMSE | 28.26 ± 1.71 | 25.25 ± 3.44 | 17.92 ± 4.86 | <0.001 | <0.001 | <0.001 |
SLUMS | 25.14 ± 3.19 | 19.50 ± 4.56 | 10.88 ± 4.64 | <0.001 | <0.001 | <0.001 |
RCS-T | 8.28 ± 1.52 | 5.42 ± 2.13 | 2.15 | <0.001 | <0.001 | <0.001 |
CDR | 0.0 ± 0.1 | 0.5 ± 0.2 | 1.5 ± 0.6 | <0.001 | <0.001 | <0.001 |
CDT | 4.7 ± 0.8 | 4.2 ± 1.2 | 2.2 ± 1.3 | <0.001 | <0.001 | <0.001 |
GDS | 2.8 ± 3.3 | 3.1 ± 3.3 | 3.7 ± 3.3 | 0.139 | - | - |
BADL | 95.46 ± 5.87 | 93.15 ± 13.22 | 83.58 ± 18.28 | <0.001 | <0.001 | 0.259 |
IADL | 14.99 ± 3.13 | 13.58 ± 3.94 | 8.07 ± 4.95 | <0.001 | <0.001 | 0.169 |
Each Test | Combınatıons of RCS + Each Sign | Combınatıons of RCS + Trıple Test | |||||
---|---|---|---|---|---|---|---|
RCS-T | Triple | RCS-T and PHTS | RCS-T and PAS | RCS-T and NAAS | RCS-T and Triple | RCS-T or Triple | |
CI | |||||||
Sensitivity % | 85.83 | 29.66 | 58.47 | 29.66 | 79.66 | 29.17 | 86.44 |
Specificity % | 88.19 | 96.51 | 96.94 | 98.69 | 92.14 | 98.7 | 85.59 |
PPV % | 78.63 | 81.40 | 90.79 | 92.11 | 83.93 | 92.11 | 75.56 |
NPV % | 92.48 | 72.70 | 81.92 | 73.14 | 89.79 | 72.76 | 92.45 |
AD | |||||||
Sensitivity % | 86.67 | 42.37 | 69.49 | 40.48 | 86.44 | 39.49 | 88.33 |
Specificity % | 90.91 | 93.75 | 94.77 | 98.61 | 93.03 | 98.89 | 85.76 |
PPV % | 65.82 | 58.14 | 73.21 | 85.71 | 71.83 | 86.82 | 56.38 |
NPV % | 97.12 | 88.82 | 93.79 | 88.73 | 97.09 | 87.06 | 97.24 |
MCI | |||||||
Sensitivity % | 73.33 | 15.52 | 78.79 | 16.95 | 61.02 | 15.25 | 61.54 |
Specificity % | 88.19 | 96.51 | 87.06 | 98.69 | 92.14 | 99.13 | 87.11 |
PPV % | 61.11 | 52.94 | 44.07 | 76.92 | 66.67 | 81.82 | 45.28 |
NPV % | 92.89 | 81.85 | 96.94 | 82.18 | 90.17 | 81.95 | 92.89 |
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Koc Okudur, S.; Dokuzlar, O.; Kaya, D.; Soysal, P.; Isik, A.T. Triple Test Plus Rapid Cognitive Screening Test: A Combination of Clinical Signs and A Tool for Cognitive Assessment in Older Adults. Diagnostics 2019, 9, 97. https://doi.org/10.3390/diagnostics9030097
Koc Okudur S, Dokuzlar O, Kaya D, Soysal P, Isik AT. Triple Test Plus Rapid Cognitive Screening Test: A Combination of Clinical Signs and A Tool for Cognitive Assessment in Older Adults. Diagnostics. 2019; 9(3):97. https://doi.org/10.3390/diagnostics9030097
Chicago/Turabian StyleKoc Okudur, Saadet, Ozge Dokuzlar, Derya Kaya, Pinar Soysal, and Ahmet Turan Isik. 2019. "Triple Test Plus Rapid Cognitive Screening Test: A Combination of Clinical Signs and A Tool for Cognitive Assessment in Older Adults" Diagnostics 9, no. 3: 97. https://doi.org/10.3390/diagnostics9030097