Association Between VEGF Expression and Diffusion Weighted Imaging in Several Tumors—A Systematic Review and Meta-Analysis
Abstract
:1. Introduction
2. Materials and Methods
Data Acquisition
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
Abbreviations
DWI | Diffusion-weighted imaging |
ADC | Apparent diffusion coefficient |
VEGF | Vascular endothelial growth factor |
IVIM | Intravoxel incoherent motion |
References
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Author, Year | Country | Design | Number of Patients | Tumor Entity | Field Strength (T) | b-Values (s/mm²) |
---|---|---|---|---|---|---|
Aoyagi et al. 2012 [17] | Japan | prospective | 17 | Esophageal cancer | 1.5 | 0;1000 |
Cong et al. 2019 [30] | China | retrospective | 52 | Esophageal cancer | 3 | 0;800 |
Heo et al. 2010 [18] | South Korea | retrospective | 27 | Hepatocellular carcinoma | 1.5 | 0;1000 |
Huang et al. 2014 [19] | China | retrospective | 36 | Hepatocellular carcinoma | 3 | 0;800 |
Lindgren et al. 2017 [20] | Finland | prospective | 40 | Ovarian cancer | 3 | 0;300;600 |
Liu et al. 2013 [21] | China | prospective | 56 | Cervical cancer | 1.5 | 0;100;0;3000 |
Ma et al. 2018 [22] | China | prospective | 39 | Prostate cancer | 3 | 0;800 |
Meng et al. 2016 [23] | China | prospective | 91 | Rectal cancer | 3 | 0;800 |
Meyer et al. 2018 [24] | Germany | retrospective | 11 | Rectal cancer | 3 | 0;1000 |
Meyer et al. 2018 [25] | Germany | retrospective | 32 | Head and neck cancer | 3 | 0;800 |
Meyer et al. 2018 [26] | Germany | retrospective | 18 | Cervical cancer | 3 | 0;1000 |
Oto et al. 2011 [27] | USA | retrospective | 73 | Prostate cancer | 1.5 | 0;1500 |
Shi et al. 2017 [28] | China | prospective | 58 | Thyroid cancer | 3 | 0;1000 |
Xie et al. 2015 [29] | China | prospective | 28 | Pancreatic cancer | 3 | 0;1000 |
Tumor Type | n (%) |
---|---|
Prostate cancer | 112 (19.4) |
Rectal cancer | 102 (17.7) |
Cervical cancer | 74 (12.8) |
Esophageal cancer | 69 (11.9) |
Hepatocellular carcinoma | 63 (10.9) |
Thyroid cancer | 58 (10.0) |
Ovarian cancer | 40 (6.9) |
Head and neck cancer | 32 (5.5) |
Pancreatic cancer | 28 (4.9) |
Total | 578 (100) |
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Meyer, H.-J.; Wienke, A.; Surov, A. Association Between VEGF Expression and Diffusion Weighted Imaging in Several Tumors—A Systematic Review and Meta-Analysis. Diagnostics 2019, 9, 126. https://doi.org/10.3390/diagnostics9040126
Meyer H-J, Wienke A, Surov A. Association Between VEGF Expression and Diffusion Weighted Imaging in Several Tumors—A Systematic Review and Meta-Analysis. Diagnostics. 2019; 9(4):126. https://doi.org/10.3390/diagnostics9040126
Chicago/Turabian StyleMeyer, Hans-Jonas, Andreas Wienke, and Alexey Surov. 2019. "Association Between VEGF Expression and Diffusion Weighted Imaging in Several Tumors—A Systematic Review and Meta-Analysis" Diagnostics 9, no. 4: 126. https://doi.org/10.3390/diagnostics9040126