Preoperative Assessment of Language Dominance through Combined Resting-State and Task-Based Functional Magnetic Resonance Imaging
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. GLM Results
3.2. RS-fMRI Results
3.3. Laterality Index
3.4. Dice Index
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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No. | Localization | Hemisphere | Tumor Classification | Surgical Intervention | Scanner | #Scans |
---|---|---|---|---|---|---|
RS | ||||||
1 | frontotemporal | right | Secondary glioblastoma IV | GA | A | 311 |
2 | temporal | left | Diffuse astrocytoma II | SB | A | 311 |
3 | frontal | left | Anaplastic astrocytoma III | AAA | A | 311 |
4 | temporal | right | * | SB | A | 311 |
5 | parietal | right | Diffuse astrocytoma II | SB | A | 299 |
6 | frontal | left | Anaplastic astrocytoma III | GA | S | 300 |
7 | frontal | right | Diffuse astrocytoma II | GA | A | 311 |
8 | parietooccipital | left | Secondary glioblastoma IV | GA | S | 300 |
9 | frontal | left | Anaplastic astrocytoma III | OB | A | 311 |
10 | frontal | left | Oligodendroglioma II | AAA | S | 450 |
11 | temporal | left | Glioblastoma IV | GA | A | 450 |
12 | temporal | right | Glioblastoma IV | GA | S | 450 |
13 | frontal | left | Secondary glioblastoma IV | GA | S | 300 |
14 | temporal | left | Meningioma WHO I | GA | S | 450 |
15 | temporal | left | Anaplastic astrocytoma III | ** | A | 311 |
16 | temporal | left | Oligoastrocytoma II | AAA | A | 450 |
17 | parietal | left | Arteriovenous malformation | GA | A | 311 |
18 | frontotemporal | left | Recurrent glioblastoma IV | GA | A | 311 |
19 | frontal | right | Anaplastic astrocytoma III | GA | S | 450 |
20 | frontoparietal | right | Recurrent glioblastoma IV | GA | A | 311 |
Peak | #Voxel | tmax | AAL Regions | % | Peak | #Voxel | tmax | AAL Regions | % |
---|---|---|---|---|---|---|---|---|---|
MNI | MNI | ||||||||
GLM antonym control | GLM verb no control | ||||||||
−52 28 2 | 4668 | 12.4 | Left inferior frontal gyrus | 63 | −46 −2 42 | 22927 | 11.1 | Left inferior frontal gyrus | 13 |
Left middle frontal gyrus | 17 | 44 22 −8 | 441 | 5.3 | Right insula | 51 | |||
Left Insula | 10 | Right inferior frontal gyrus | 24 | ||||||
2 −70 6 | 4520 | 7.1 | Left lingual gyrus | 24 | 48 −32 4 | 117 | 4.5 | Right superior temporal gyrus | 77 |
Left calcarine sulcus | 18 | Right middle temporal gyrus | 10 | ||||||
Left cuneus | 12 | 24 10 6 | 481 | 4.7 | Right putamen | 36 | |||
Right calcarine sulcus | 12 | Right caudate nucleus | 16 | ||||||
34 22 −6 | 1447 | 7.2 | Right inferior frontal gyrus | 59 | −28 −50 52 | 2860 | 9.2 | Left superior parietal lobule | 33 |
−58 −46 0 | 637 | 6.1 | Left middle temporal gyrus | 80 | Left inferior parietal lobule | 31 | |||
48 −26 −6 | 130 | 4.6 | Right superior temporal gyrus | 39 | Left postcentral gyrus | 13 | |||
Right middle temporal gyrus | 28 | 28 −58 44 | 1623 | 9.8 | Right superior parietal lobule | 30 | |||
−4 24 36 | 1712 | 7.1 | Left supplementary motor area | 31 | Right inferior parietal lobule | 15 | |||
Left medial frontal gyrus | 24 | Right postcentral gyrus | 14 | ||||||
Right supplementary motor area | 13 | RS antonym control | |||||||
GLM antonym no control | −48 42 −10 | 2883 | 5.9 | Left inferior frontal gyrus | 65 | ||||
28 −90 8 | 3472 | 6.6 | Right lobule VI of cerebellar hemisphere | 17 | Left middle frontal gyrus | 18 | |||
Right middle occipital gyrus | 15 | −106 | 352 | 4.9 | Left middle temporal gyrus | 80 | |||
Right inferior occipital gyrus | 14 | −14 4 12 | 111 | 5.4 | Left caudate nucleus | 54 | |||
Right fusiform gyrus | 13 | Left putamen | 19 | ||||||
Right inferior temporal gyrus | 11 | −50 −54 38 | 512 | 6.0 | Left inferior parietal lobule | 51 | |||
−54 −38 6 | 4753 | 7.3 | Left middle occipital gyrus | 24 | Left supramarginal gyrus | 29 | |||
Left fusiform gyrus | 19 | Left angular gyrus | 19 | ||||||
Left middle temporal gyrus | 15 | −2 24 54 | 674 | 5.3 | Left supplementary motor area | 66 | |||
Left inferior occipital gyrus | 15 | Left medial frontal gyrus | 27 | ||||||
−18 0 18 | 9513 | 9.8 | Left inferior frontal gyrus | 30 | RS antonym no control | ||||
Left precentral gyrus | 18 | −58 6 16 | 109 | 4.3 | Left inferior frontal gyrus | 88 | |||
34 24 0 | 954 | 6.9 | Right inferior frontal gyrus | 51 | Left precentral gyrus | 10 | |||
Right insula | 24 | −20 −70 34 | 128 | 4.4 | Left superior occipital | 40 | |||
−50 | 204 | 6.8 | Left Putamen | 12 | Left superior parietal lobule | 33 | |||
36 −32 2 | 128 | 5.4 | Right superior temporal gyrus | 58 | Left middle occipital gyrus | 19 | |||
18 −6 22 | 396 | 6.2 | Right caudate nucleus | 27 | −40 −4 50 | 141 | 4.0 | Left precentral gyrus | 98 |
Right pallidum | 15 | RS verb control | |||||||
Right putamen | 12 | −46 32 −2 | 3170 | 6.2 | Left inferior frontal gyrus | 63 | |||
28 −58 44 | 851 | 7.6 | Right superior parietal lobule | 35 | Left middle frontal gyrus | 21 | |||
Right inferior parietal lobule | 15 | −104 | 292 | 4.5 | Left middle temporal gyrus | 86 | |||
Right angular gyrus | 13 | −16 10 12 | 194 | 5.5 | Left caudate nucleus | 49 | |||
−6 8 60 | 1496 | 10.8 | Left supplementary motor area | 55 | Left putamen | 29 | |||
Right supplementary motor area | 26 | −50 −54 34 | 790 | 5.6 | Left inferior parietal lobule | 42 | |||
28 −4 56 | 183 | 4.4 | Right superior frontal gyrus | 40 | Left angular gyrus | 32 | |||
Right middle frontal gyrus | 31 | Left supramarginal gyrus | 23 | ||||||
Right precentral gyrus | 11 | −2 26 50 | 818 | 5.0 | Left supplementary motor area | 47 | |||
GLM verb control | Left medial frontal gyrus | 41 | |||||||
−44 22 −2 | 4253 | 8.1 | Left inferior frontal gyrus | 62 | RS verb no control | ||||
Left middle frontal gyrus | 24 | −20 −66 40 | 722 | Left superior parietal lobule | 57 | ||||
−2 −90 20 | 2879 | 6.8 | Left cuneus | 19 | Left middle occipital gyrus | 16 | |||
Left calcarine sulcus | 17 | Left inferior parietal lobule | 12 | ||||||
Left lingual gyrus | 16 | −40 −2 42 | 590 | 5.1 | Left precentral gyrus | 79 | |||
Right cuneus | 13 | Left inferior frontal gyrus | 11 | ||||||
Right lingual gyrus | 11 | 32 −70 46 | 792 | 5.1 | Right superior parietal lobule | 44 | |||
−82 | 745 | 6.3 | Left middle temporal gyrus | 80 | Right inferior parietal lobule | 18 | |||
34 24 −4 | 341 | 5.8 | Right insula | 50 | Right superior occipital gyrus | 16 | |||
Right inferior frontal gyrus | 36 | Right angular gyrus | 12 | ||||||
−60 −54 18 | 200 | 4.7 | Left middle temporal gyrus | 53 | |||||
Left supramarginal gyrus | 22 | ||||||||
Left angular gyrus | 17 | ||||||||
−4 18 60 | 1508 | 6.9 | Left medial frontal gyrus | 38 | |||||
Left supplementary motor area | 30 | ||||||||
Left anterior cingulum | 11 |
Dice Index Correlations | Verb w/o LCC | Anto w/o LCC | Verb with LCC | Anto with LCC |
---|---|---|---|---|
mean | 0.276 | 0.2825 | 0.3065 | 0.2906 |
standard deviation | 0.06102 | 0.07639 | 0.10682 | 0.08484 |
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Ott, C.; Rosengarth, K.; Doenitz, C.; Hoehne, J.; Wendl, C.; Dodoo-Schittko, F.; Lang, E.; Schmidt, N.O.; Goldhacker, M. Preoperative Assessment of Language Dominance through Combined Resting-State and Task-Based Functional Magnetic Resonance Imaging. J. Pers. Med. 2021, 11, 1342. https://doi.org/10.3390/jpm11121342
Ott C, Rosengarth K, Doenitz C, Hoehne J, Wendl C, Dodoo-Schittko F, Lang E, Schmidt NO, Goldhacker M. Preoperative Assessment of Language Dominance through Combined Resting-State and Task-Based Functional Magnetic Resonance Imaging. Journal of Personalized Medicine. 2021; 11(12):1342. https://doi.org/10.3390/jpm11121342
Chicago/Turabian StyleOtt, Christian, Katharina Rosengarth, Christian Doenitz, Julius Hoehne, Christina Wendl, Frank Dodoo-Schittko, Elmar Lang, Nils Ole Schmidt, and Markus Goldhacker. 2021. "Preoperative Assessment of Language Dominance through Combined Resting-State and Task-Based Functional Magnetic Resonance Imaging" Journal of Personalized Medicine 11, no. 12: 1342. https://doi.org/10.3390/jpm11121342