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Applied Sciences
Volume 11
Issue 24
10.3390/app112411602
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Review

Recent Advances of Integrative Bio-Omics Technologies to Improve Type 1 Diabetes (T1D) Care

by
Nisha Karwal
1,
Megan Rodrigues
1,
David D. Williams
1,
Ryan J. McDonough
2 and
Diana Ferro
2,*
1
Children’s Mercy Research Institute, Hospital and Clinics, Kansas City, MO 64108, USA
2
Department of Pediatrics, University of Missouri Kansas City, Kansas City, MO 64108, USA
*
Author to whom correspondence should be addressed.
Appl. Sci. 2021, 11(24), 11602; https://doi.org/10.3390/app112411602
Submission received: 11 November 2021 / Revised: 29 November 2021 / Accepted: 2 December 2021 / Published: 7 December 2021
(This article belongs to the Special Issue Evolution of Modern Molecular Biology Applications)
Review Reports Versions Notes

Abstract

Type 1 diabetes (T1D) is a complex autoimmune disease that currently cannot be cured, only managed. Optimal treatment the of T1D symptoms, requires a multidisciplinary care team, including endocrinologists, educators, primary care providers, health care specialists, genetic counselors, and data scientists. This review summarizes how an integrative approach to T1D drives innovation and quality improvements in health care. Specifically, we highlight how “-omics” technologies facilitate the understanding of different aspects of the disease, including prevention, pathogenesis, diagnostics, and treatment. Furthermore, we explore how biological data can be combined with personal and electronic health records to tailor medical interventions to the individual’s biology and lifestyle. We conclude that truly personalized medicine will not be limited to one data source but will emerge from the integration of multiple sources and disciplines that together will support individuals with T1D in their everyday life.
Keywords: genomics; diabetes; big data; T1D genomics; diabetes; big data; T1D

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MDPI and ACS Style

Karwal, N.; Rodrigues, M.; Williams, D.D.; McDonough, R.J.; Ferro, D. Recent Advances of Integrative Bio-Omics Technologies to Improve Type 1 Diabetes (T1D) Care. Appl. Sci. 2021, 11, 11602. https://doi.org/10.3390/app112411602

AMA Style

Karwal N, Rodrigues M, Williams DD, McDonough RJ, Ferro D. Recent Advances of Integrative Bio-Omics Technologies to Improve Type 1 Diabetes (T1D) Care. Applied Sciences. 2021; 11(24):11602. https://doi.org/10.3390/app112411602

Chicago/Turabian Style

Karwal, Nisha, Megan Rodrigues, David D. Williams, Ryan J. McDonough, and Diana Ferro. 2021. "Recent Advances of Integrative Bio-Omics Technologies to Improve Type 1 Diabetes (T1D) Care" Applied Sciences 11, no. 24: 11602. https://doi.org/10.3390/app112411602

APA Style

Karwal, N., Rodrigues, M., Williams, D. D., McDonough, R. J., & Ferro, D. (2021). Recent Advances of Integrative Bio-Omics Technologies to Improve Type 1 Diabetes (T1D) Care. Applied Sciences, 11(24), 11602. https://doi.org/10.3390/app112411602

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