Walk Locomotion Kinematic Changes in a Model of Penetrating Hippocampal Injury in Male/Female Mice and Rats
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals and Experimental Study Groups
2.2. Brain Injury Model
2.3. Tunnel Walk Recordings
2.4. Dissimilarity Factor and Vertical Displacement Analysis
2.5. Statistical Analysis
2.6. Histological Analysis
3. Results
3.1. Vertical Displacement in Hindlimbs Metatarsus, Ankle, and Knee in Rats and Mice
3.2. The Ankle VD in Intact Rats Differs from That in Intact Mice
3.3. The Knee VD Differs between Intact Rats versus Intact Mice
3.4. DF in Rats and Mice’s Metatarsus, Ankle, and Knee Joints
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Alpirez, J.; Leon-Moreno, L.C.; Aguilar-García, I.G.; Castañeda-Arellano, R.; Dueñas-Jiménez, J.M.; Asencio-Piña, C.R.; Dueñas-Jiménez, S.H. Walk Locomotion Kinematic Changes in a Model of Penetrating Hippocampal Injury in Male/Female Mice and Rats. Brain Sci. 2023, 13, 1545. https://doi.org/10.3390/brainsci13111545
Alpirez J, Leon-Moreno LC, Aguilar-García IG, Castañeda-Arellano R, Dueñas-Jiménez JM, Asencio-Piña CR, Dueñas-Jiménez SH. Walk Locomotion Kinematic Changes in a Model of Penetrating Hippocampal Injury in Male/Female Mice and Rats. Brain Sciences. 2023; 13(11):1545. https://doi.org/10.3390/brainsci13111545
Chicago/Turabian StyleAlpirez, Jonatan, Lilia Carolina Leon-Moreno, Irene Guadalupe Aguilar-García, Rolando Castañeda-Arellano, Judith Marcela Dueñas-Jiménez, Cesar Rodolfo Asencio-Piña, and Sergio Horacio Dueñas-Jiménez. 2023. "Walk Locomotion Kinematic Changes in a Model of Penetrating Hippocampal Injury in Male/Female Mice and Rats" Brain Sciences 13, no. 11: 1545. https://doi.org/10.3390/brainsci13111545