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Microarrays, Volume 5, Issue 1

2016 March - 6 articles

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Articles (6)

  • Article
  • Open Access
22 Citations
7,197 Views
25 Pages

Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders

  • Ling Z. Morgan,
  • Brandi Rollins,
  • Adolfo Sequeira,
  • William Byerley,
  • Lynn E. DeLisi,
  • Alan F. Schatzberg,
  • Jack D. Barchas,
  • Richard M. Myers,
  • Stanley J. Watson and
  • Marquis P. Vawter
  • + 2 authors

Genome-wide association studies of schizophrenia encompassing the major histocompatibility locus (MHC) were highly significant following genome-wide correction. This broad region implicates many genes including the MHC complex class II. Within this i...

  • Article
  • Open Access
7 Citations
9,181 Views
10 Pages

A Double-Hybridization Approach for the Transcription- and Amplification-Free Detection of Specific mRNA on a Microarray

  • Michaela Haider,
  • Thomas Haselgrübler,
  • Alois Sonnleitner,
  • Fritz Aberger and
  • Jan Hesse

A double-hybridization approach was developed for the enzyme-free detection of specific mRNA of a housekeeping gene. Targeted mRNA was immobilized by hybridization to complementary DNA capture probes spotted onto a microarray. A second hybridization...

  • Review
  • Open Access
22 Citations
7,924 Views
15 Pages

Microarray technologies inspired the development of carbohydrate arrays. Initially, carbohydrate array technology was hindered by the complex structures of glycans and their structural variability. The first designs of glycoarrays focused on the HTP...

  • Article
  • Open Access
9 Citations
6,900 Views
12 Pages

Split hand/foot malformation (SHFM) is a limb malformation with underdeveloped or absent central digital rays, clefts of hands and feet, and variable syndactyly of the remaining digits. There are six types of SHFM. Here, we report a boy with SHFM typ...

  • Review
  • Open Access
14 Citations
11,120 Views
23 Pages

Cytogenetic analysis is essential for the diagnosis and prognosis of hematopoietic neoplasms in current clinical practice. Many hematopoietic malignancies are characterized by structural chromosomal abnormalities such as specific translocations, inve...

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Microarrays - ISSN 2076-3905