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Journal of Clinical Medicine, Volume 11, Issue 21

November-1 2022 - 377 articles

Cover Story: The aim of our study was the histological evaluation of uterus remnants and endometriotic tissue in patients with MRKH syndrome and its comparison to endometriosis patient samples without Mullerian anomaly. Endometrium of the remnants and endometriotic lesions in MRKH patients displayed a high expression of hormonal receptors. In two patients, the Ki67 proliferation index was significantly increased in peritoneal endometriotic lesions compared to the endometrium of the remnants. In contrast, endometrium and endometriotic lesions of endometriosis patients did not display any differences in the Ki67 proliferation index. Our results show immunohistochemical variability between uterus remnants and endometriotic lesions in patients with MRKH syndrome compared to endometriosis patients, thus indicating a possible explanation model of the yet-unknown etiology of endometriosis. View this paper
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Articles (377)

  • Article
  • Open Access
2 Citations
4,737 Views
10 Pages

Optimal Timing of Cholecystectomy for Patients with Concurrent Acute Cholecystitis and Acute Cholangitis after Successful Biliary Drainage by Interventional Endoscopic Retrograde Cholangiopancreatography

  • Yau-Ren Chang,
  • Chi-Huan Wu,
  • Huan-Wu Chen,
  • Yu-Liang Hung,
  • Chia-Hsiang Hu,
  • Ruo-Yi Huang,
  • Min-Jung Wu,
  • Hao-Wei Kou,
  • Ming-Yang Chen and
  • Chun-Yi Tsai
  • + 6 authors

7 November 2022

Background: Concurrent acute cholecystitis and acute cholangitis is a unique clinical situation. We tried to investigate the optimal timing of cholecystectomy after adequate biliary drainage under this condition. Methods: From January 2012 to Novembe...

  • Article
  • Open Access
1 Citations
2,292 Views
12 Pages

7 November 2022

In the routine pharmacist’s medication review in ambulatory care and nursing homes in Germany, clinical diagnoses are often insufficiently considered as they are frequently not accessible to pharmacists and their electronic support tools. This may le...

  • Article
  • Open Access
10 Citations
3,410 Views
9 Pages

Surgical and Medical Aspects of the Initial Treatment of Biliary Atresia: Position Paper

  • Mark Davenport,
  • Omid Madadi-Sanjani,
  • Christophe Chardot,
  • Henkjan J. Verkade,
  • Saul J. Karpen and
  • Claus Petersen

7 November 2022

Biliary atresia, a fibro-obliterative disease of the newborn, is usually initially treated by Kasai portoenterostomy, although there are many variations in technique and different options for post-operative adjuvant medical therapy. A questionnaire o...

  • Article
  • Open Access
7 Citations
2,702 Views
11 Pages

Prediction Value of KREBS Von Den Lungen-6 (KL-6) Biomarker in COVID-19 Patients: A Systematic Review and Meta-Analysis

  • Michal Matuszewski,
  • Lukasz Szarpak,
  • Zubaid Rafique,
  • Frank W. Peacock,
  • Michal Pruc,
  • Piotr Szwed,
  • Francesco Chirico,
  • Alla Navolokina,
  • Jerzy R. Ladny and
  • Andrea Denegri

7 November 2022

The SARS-CoV-2 (COVID-19) pandemic is a major issue that necessitates the use of cutting-edge disease prediction models. The aim of the study was to assess the existing evidence regarding association between Krebs von den Lungen-6 levels and COVID-19...

  • Article
  • Open Access
4 Citations
2,856 Views
11 Pages

7 November 2022

Background: Tongue pressure values in patients with dysphagia are reported to be significantly lower than those in healthy controls. The aim of this study was to measure the maximum tongue pressure (MTP) values after extubation in order to assess the...

  • Article
  • Open Access
12 Citations
2,742 Views
14 Pages

Cardiac Troponin I Reveals Diagnostic and Prognostic Superiority to Aminoterminal Pro-B-Type Natriuretic Peptide in Sepsis and Septic Shock

  • Jan Forner,
  • Tobias Schupp,
  • Kathrin Weidner,
  • Jonas Rusnak,
  • Schanas Jawhar,
  • Floriana Dulatahu,
  • Lea Marie Brück,
  • Michael Behnes,
  • Ursula Hoffmann and
  • Thomas Bertsch
  • + 2 authors

7 November 2022

Data regarding the prognostic value of cardiac biomarkers in patients suffering from sepsis or septic shock is scarce. Studies investigating the prognostic role of cardiac biomarkers in patients with sepsis and septic shock were commonly published pr...

  • Case Report
  • Open Access
1 Citations
2,334 Views
8 Pages

7 November 2022

Polyhydramnios represents a complication found in 0.2–2% of pregnancies, and it is usually diagnosed between 31 and 36 weeks of pregnancy. Although most cases of polyhydramnios are idiopathic, maternal diabetes or foetal malformations constitut...

  • Review
  • Open Access
43 Citations
6,850 Views
20 Pages

PSMA Expression in Solid Tumors beyond the Prostate Gland: Ready for Theranostic Applications?

  • Chiara Lauri,
  • Lorenzo Chiurchioni,
  • Vincenzo Marcello Russo,
  • Luca Zannini and
  • Alberto Signore

7 November 2022

In the past decades, the expanding use of prostate-specific membrane antigen (PSMA) imaging for prostate cancer has led to the incidental detection of a lot of extra-prostatic malignancies showing an increased uptake of PSMA. Due to these incidental...

  • Article
  • Open Access
1,725 Views
10 Pages

Reticulated Platelets and Their Relationship with Endothelial Progenitor Cells during the Acute Phase of ST-Elevation Myocardial Infarction

  • Nili Schamroth Pravda,
  • Mark Kheifets,
  • Maya Wiessman,
  • Dorit Leshem-Lev,
  • Hana Vaknin Assa,
  • Ran Kornowski,
  • Yeela Talmor-Barkan and
  • Leor Perl

7 November 2022

Introduction: Endothelial progenitor cells (EPC) and reticulated platelets (RP) have central roles in the thrombotic and angiogenetic interactions during ST-elevation myocardial infarction (STEMI). The EPC and RP response in patients with STEMI treat...

  • Article
  • Open Access
6 Citations
2,437 Views
13 Pages

Improvement of Mucosal Lesion Diagnosis with Machine Learning Based on Medical and Semiological Data: An Observational Study

  • Antoine Dubuc,
  • Anissa Zitouni,
  • Charlotte Thomas,
  • Philippe Kémoun,
  • Sarah Cousty,
  • Paul Monsarrat and
  • Sara Laurencin

7 November 2022

Despite artificial intelligence used in skin dermatology diagnosis is booming, application in oral pathology remains to be developed. Early diagnosis and therefore early management, remain key points in the successful management of oral mucosa cancer...

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J. Clin. Med. - ISSN 2077-0383Creative Common CC BY license