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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Musculoskeletal Spine Disorders: Clinical Management, Rehabilitation Strategies, and Technological Innovations

edited by

Maria Chiara Maccarone

Nicola Manocchio

and Calogero Foti

submission deadline 14 Sep 2026 | 2 articles | Viewed by 1465 | Submission Open

Keywords: spine disorders; rehabilitation; physical exercise; low back pain; scoliosis; adolescent idiopathic scoliosis

(This special issue belongs to the Section Orthopedics)

Biomarkers and Diagnostics in Neurological Diseases

edited by Maria Ioanna Stefanou

submission deadline 15 Sep 2026 | 11 articles | Viewed by 20983 | Submission Open

Keywords: biomarkers; neurological diseases; diagnosis; lipoprotein(a); neurofilament protein; tau peptide; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Advances in Diagnosis and Treatment of Endometriosis

edited by

Arrigo Fruscalzo

and

Anis Feki

submission deadline 15 Sep 2026 | 6 articles | Viewed by 12600 | Submission Open

Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone

(This special issue belongs to the Section Obstetrics & Gynecology)

Thyroid Disease: Updates from Diagnosis to Treatment: 2nd Edition

edited by

Luca Giovanella

and

Petra Petranović Ovčariček

submission deadline 15 Sep 2026 | 7 articles | Viewed by 9906 | Submission Open

Keywords: autoimmune thyroid diseases; thyroiditis; thyroid cancers; PET/CT; hyperthyroidism

(This special issue belongs to the Section Endocrinology & Metabolism)

Current Challenges in Clinical Dentistry: 3rd Edition

edited by

Eiji Tanaka

and

Susumu Abe

submission deadline 15 Sep 2026 | 3 articles | Viewed by 5325 | Submission Open

Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities

edited by Rami S Kantar

submission deadline 15 Sep 2026 | 5 articles | Viewed by 4721 | Submission Open

Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Latest Advances in Thoracic Surgery: 2nd Edition

edited by

Hideki Ujiie

submission deadline 15 Sep 2026 | 2 articles | Viewed by 4311 | Submission Open

Keywords: lung cancer; surgical oncology; robotic surgery; thoracic surgery; lung diseases; minimally invasive surgery

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Obesity and Bariatric Surgery—2nd Edition

edited by Valentin Mocanu and Jerry Dang

submission deadline 15 Sep 2026 | 4 articles | Viewed by 3496 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment

(This special issue belongs to the Section Endocrinology & Metabolism)

Risk Prediction in Mechanical Circulatory Support (MCS) and Cardiac Transplantation

edited by

Nandini Nair

submission deadline 15 Sep 2026 | 3 articles | Viewed by 3245 | Submission Open

Keywords: advanced heart failure; mechanical circulatory support (MCS); cardiac transplantation; heart transplantation; risk prediction

(This special issue belongs to the Section Cardiology)

Sports Injuries: Emerging Trends in Risk Mitigation, Management and Recovery

edited by

Luis Suárez-Arrones

and Jose Asian-Clemente

submission deadline 15 Sep 2026 | 3 articles | Viewed by 1522 | Submission Open

Keywords: injury prevention; rehabilitation; muscle; return-to-sport; surgery; therapy; testing; regenerative medicine; ultrasound; MRI; sports medicine

(This special issue belongs to the Section Sports Medicine)

Advances in Pancreatic Cancer: Diagnosis and Therapy

edited by Eleonora Lai,

Nicola Silvestris

and

Mario Scartozzi

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1519 | Submission Open

Keywords: pancreatic cancer diagnosis; endoscopic ultrasound; neoadjuvant chemotherapy; surgical resection; targeted therapy; immunotherapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cancers: Clinical Radiation Therapy

edited by Julianne M. Pollard-Larkin

submission deadline 15 Sep 2026 | 1 articles | Viewed by 1088 | Submission Open

Keywords: reirradiation; tissue tolerance; image registration; treatment planning; dose accumulation

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Advances in Cardiac Resynchronization Treatment: 2nd Edition

edited by

George Leventopoulos

, Konstantinos A. Gatzoulis, Konstantinos Aronis and

Dimitris L. Tsiachris

submission deadline 15 Sep 2026 | 1 articles | Viewed by 997 | Submission Open

Keywords: conduction system; risk stratification; resynchronization; cardiac pacing; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Cardiovascular Disease in MASLD: New Advances in Therapeutic Targets

edited by

Alfredo Caturano

submission deadline 15 Sep 2026 | 1 articles | Viewed by 979 | Submission Open

Keywords: MASLD; cardiovascular disease (CVD); metabolic dysfunction; steatotic liver disease; insulin resistance; dyslipidemia; atherosclerosis; inflammation; GLP-1 receptor agonists; SGLT2 inhibitors; lipid-lowering therapies; cardiometabolic risk; clinical trials; therapeutic targets

(This special issue belongs to the Section Cardiovascular Medicine)

Cardiac Arrest: Appropriate Prognostication and Therapeutic Options

edited by

Jae Hoon Lee

and Jin-hong Min

submission deadline 15 Sep 2026 | 1 articles | Viewed by 823 | Submission Open

Keywords: cardiac arrest; prognosis; hypothermia, induced; resuscitation; magnetic resonance imaging; electroencephalog-raphy; blood pressure; hypoxia-ischemia, brain; extracorporeal membrane oxygenation

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Endoscopic Techniques for Gastrointestinal Diseases

edited by Alberto Tringali

submission deadline 15 Sep 2026 | 1 articles | Viewed by 654 | Submission Open

Keywords: hepatobiliary disease; pancreatic disease; ERCP; interventional EUS; cholangiopancreatoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Pulmonary Arterial Hypertension: Emerging Therapies and Clinical Outcomes

edited by Namita Sood

submission deadline 15 Sep 2026 | Viewed by 386 | Submission Open

Keywords: pulmonary arterial hypertension (PAH); PAH therapy; emerging treatments; sotatercept; inhaled therapy; targeted pharmacotherapy; combination therapy; therapeutic efficacy; pulmonary vascular imaging

(This special issue belongs to the Section Respiratory Medicine)

State of the Art of Lung Surgery: Modern Horizons in Lung Cancer Treatment

edited by

Alessio Mariolo

and Edouard Sage

submission deadline 15 Sep 2026 | Viewed by 347 | Submission Open

Keywords: lung-cancer-surgery; thoracic oncology; RATS; VATS; induction therapy; neoadjuvant-immunotherapy; non-intubated thoracic surgery; NITS; segmentectomy; lung-sparing surgery; 3D-reconstruction

(This special issue belongs to the Section General Surgery)

Recent Clinical Updates on Vascular and Endovascular Surgery

edited by

Mª Lourdes Del Río-Solá

and

Sergi Bellmunt-Montoya

submission deadline 15 Sep 2026 | Viewed by 340 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic disease; abdominal aortic aneurysm; peripheral arterial disease; chronic venous disease; endovascular repair; open vascular surgery

(This special issue belongs to the Section Vascular Medicine)

Innovations and Advancements in Spine Surgery

edited by Mitchell K. Ng

submission deadline 15 Sep 2026 | Viewed by 310 | Submission Open

Keywords: spine surgery; minimally invasive spine surgery; robotic-assisted spine surgery; spinal navigation; endoscopic spine surgery; spinal implant; biologics and regenerative therapies; perioperative optimization; patient-reported outcomes; value-based spine care; surgical innovation

(This special issue belongs to the Section Orthopedics)

New Insights into Acute Care and Emergency Surgery: 2nd Edition

edited by Jacob Chen and Avi Benov

submission deadline 15 Sep 2026 | Viewed by 273 | Submission Open

Keywords: trauma surgery; emergency surgery; acute care; anesthesia; ICU

(This special issue belongs to the Section General Surgery)

Innovations in Advanced Heart Failure Detection and Management

edited by Vinh Q. Chau and Nikhil Narang

submission deadline 15 Sep 2026 | Viewed by 256 | Submission Open

Keywords: advanced heart failure; systolic heart failure; mechanical circulatory support; left ventricular assist device; heart transplantation outcomes

(This special issue belongs to the Section Cardiology)

Clinical Advances in Kidney Transplantation

edited by

Florin Ioan Elec

and

Oana Antal

submission deadline 18 Sep 2026 | 7 articles | Viewed by 9428 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Sep 2026 | 9 articles | Viewed by 30227 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Sep 2026 | 12 articles | Viewed by 27221 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 20 Sep 2026 | 5 articles | Viewed by 20708 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Acute Pancreatitis and Its Complications: Current Diagnostics and Management

edited by

Beata Jabłońska

submission deadline 20 Sep 2026 | 5 articles | Viewed by 20110 | Submission Open

Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Skin Disease and Inflammation

edited by

Taihao Quan

submission deadline 20 Sep 2026 | 4 articles | Viewed by 17110 | Submission Open

Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea

(This special issue belongs to the Section Dermatology)

Clinical Advances in Musculoskeletal Disorders: 2nd Edition

edited by

Peter V. Giannoudis

and Sushrut Babhulkar

submission deadline 20 Sep 2026 | 7 articles | Viewed by 13438 | Submission Open

Keywords: musculoskeletal disorders; disability; pain; inflammation; arthritis

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in Clinical Exercise for Health

edited by

Pedro Miguel Forte

and Joana Ribeiro

submission deadline 20 Sep 2026 | 8 articles | Viewed by 13410 | Submission Open

Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology

(This special issue belongs to the Section Sports Medicine)

Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy

edited by

Athanasios Samaras

and

Andreas S. Papazoglou

submission deadline 20 Sep 2026 | 5 articles | Viewed by 12884 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology

(This special issue belongs to the Section Cardiology)

Current Challenges and New Perspectives in Liver Transplantation

edited by

Anna Mrzljak

and

Quirino Lai

submission deadline 20 Sep 2026 | 11 articles | Viewed by 11014 | Submission Open

Keywords: liver transplantation; graft survival; immunosuppression; organ allocation; hepatocellular carcinoma; MASLD; donor shortage; transplant outcomes; innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Perspectives on the Diagnosis and Treatment of Cardiomyopathies

edited by Luca Arcari

submission deadline 20 Sep 2026 | 5 articles | Viewed by 9333 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

(This special issue belongs to the Section Cardiology)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Sep 2026 | 6 articles | Viewed by 8974 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

Cognitive Impairment, Dementia and Depression in Older Adults

edited by Seong Jae Kim and Ilhan Choo

submission deadline 20 Sep 2026 | 3 articles | Viewed by 7390 | Submission Open

Keywords: cognitive impairment; dementia; depression; Parkinson’s disease; artificial intelligence (AI); predictive modeling

(This special issue belongs to the Section Geriatric Medicine)

Advances in Minimally Invasive Gynecologic Surgery: Optimizing Outcomes and Perioperative Strategies

edited by

Raanan Meyer

submission deadline 20 Sep 2026 | 3 articles | Viewed by 5602 | Submission Open

Keywords: minimally invasive gynecologic surgery; MIGS; laparoscopy; robotic surgery; endometrial cancer; endometriosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood

edited by Kamila Chęcińska and

Maciej Sikora

submission deadline 20 Sep 2026 | 5 articles | Viewed by 5591 | Submission Open

Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Modern Gynecological Surgery: Clinical Updates and Perspectives

edited by

Rudy Leon De Wilde

Harald Krentel

and Maya Sophie de Wilde

submission deadline 20 Sep 2026 | 5 articles | Viewed by 5482 | Submission Open

Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’s health care

(This special issue belongs to the Section Obstetrics & Gynecology)

New Advances in Systemic Lupus Erythematosus (SLE)

edited by

Chang-Hee Suh

submission deadline 20 Sep 2026 | 2 articles | Viewed by 5264 | Submission Open

Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life

(This special issue belongs to the Section Immunology & Rheumatology)

New Insights into the Management of Psoriasis and Immune-Mediated Dermatoses

edited by Federico Bardazzi and Riccardo Balestri

submission deadline 20 Sep 2026 | 6 articles | Viewed by 5054 | Submission Open

Keywords: psoriasis; immune-mediated inflammatory diseases; biologic therapy; small-molecule drugs; personalized treatment; real-world evidence; comorbidities; patient-centered care

(This special issue belongs to the Section Dermatology)

Advances in Antithrombotic Therapy in Cardiovascular Medicine

edited by Daniele Giacoppo and Antonio Greco

submission deadline 20 Sep 2026 | 6 articles | Viewed by 4909 | Submission Open

Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis

(This special issue belongs to the Section Cardiovascular Medicine)

Innovations and Advances in Primary Care and Family Medicine

edited by

Geert Goderis

submission deadline 20 Sep 2026 | 5 articles | Viewed by 4168 | Submission Open

Keywords: primary care; family medicine; integrated care; chronic disease management; multimorbidity; mental health; digital health; artificial intelligence; population health management; implementation research; health services research; interdisciplinary collaboration; evidence-based practice

(This special issue belongs to the Section Epidemiology & Public Health)

Bladder Cancer: Diagnosis and Treatments

edited by

Stanislav Źiaran

submission deadline 20 Sep 2026 | 2 articles | Viewed by 4158 | Submission Open

Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy

(This special issue belongs to the Section Nephrology & Urology)

Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices

edited by

Jae-Yeol Lee

submission deadline 20 Sep 2026 | 5 articles | Viewed by 4147 | Submission Open

Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Liquid Biopsies in Oral Cancer: Advances and New Perspectives

edited by

Óscar Rapado-González

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3862 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Postpartum Depression: What Happened to My Wife?

edited by

Sara Albuquerque

Ana Filipa Beato

and

Stephanie Alves

submission deadline 20 Sep 2026 | 4 articles | Viewed by 3821 | Submission Open

Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life

(This special issue belongs to the Section Mental Health)

Minimally Invasive and Endoscopic Neurosurgery

edited by

Nikolaos Gkantsinikoudis

, Vassilios Tsitouras and Stylianos Kapetanakis

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3790 | Submission Open

Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy

(This special issue belongs to the Section Clinical Neurology)

Residual Risk in High-Risk Patients Undergoing Percutaneous Coronary Intervention

edited by

Giampiero Vizzari

and

Antonio Micari

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3749 | Submission Open

Keywords: cardiology; precision medicine; residual risk; acute coronary syndrome; percutaneous coronary intervention; PCI

(This special issue belongs to the Section Cardiology)

Innovations in Emergency and Critical Care Medicine

edited by Yoshiaki Iwashita

submission deadline 20 Sep 2026 | 3 articles | Viewed by 3631 | Submission Open

Keywords: emergency; artificial intelligence; Tele-ICU; point of care; electrical impedance tomography

(This special issue belongs to the Section Intensive Care)

Advancements and Challenges in Retina Surgery: Second Edition

edited by Joaquín Marticorena and

Javier Zarranz-Ventura

submission deadline 20 Sep 2026 | 2 articles | Viewed by 3562 | Submission Open

Keywords: retina; vitreoretinal diseases; vitreotomes; optical coherence tomography; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

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