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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Updates on Maternal Fetal Medicine submission deadline 25 Jul 2025 | 8 articles | Viewed by 17720
Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Gynecological Surgery: New Clinical Insights and Challenges
edited by Francesco Plotti
submission deadline 25 Jul 2025 | 10 articles | Viewed by 13006
Keywords: minimally invasive surgery; urogynecologic surgery; complications; gynecologic oncology; robotic surgery; benign gynecologic surgery; vaginal surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Debates in Minimally Invasive Glaucoma Surgery (MIGS)
edited by
submission deadline 25 Jul 2025 | 9 articles | Viewed by 10115
Keywords: MIGS (minimally invasive glaucoma surgery); schlemm’ s canal opening surgery; trabeculotomy; trabeculectomy; collector channel; histology; intraocular pressure; surgical success
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Hemodialysis
edited by Maurizio Bossola
submission deadline 25 Jul 2025 | 8 articles | Viewed by 8213
Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy
(This special issue belongs to the Section Nephrology & Urology)
Clinical Perspectives in Trauma and Orthopedic Surgery
edited by
submission deadline 25 Jul 2025 | 4 articles | Viewed by 5430
Keywords: trauma; sports; ankle; knee; hip; cartilage regeneration; bone regeneration; orthopedic surgery
(This special issue belongs to the Section Orthopedics)
Thoracic Imaging in Cardiovascular and Pulmonary Disease Diagnosis
edited by Marco Sperandeo and
submission deadline 25 Jul 2025 | 4 articles | Viewed by 5034
Keywords: thoracic imaging; cardiovascular diagnosis; pulmonary disease; clinical medicine; diagnostic accuracy; imaging techniques; thoracic ultrasound; patient care
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Foot and Ankle Surgery: State of the Art and Future Perspectives
edited by Sung Jae Kim and Jaehwang Song
submission deadline 25 Jul 2025 | 5 articles | Viewed by 4544
Keywords: foot and ankle surgery; hallux disorders; lesser toe problem; diabetic foot salvage; calcaneal fracture; pilon fracture; ligament disorder
(This special issue belongs to the Section Orthopedics)
Multiple Myeloma: Advances in Diagnosis and Treatment
edited by
submission deadline 25 Jul 2025 | 2 articles | Viewed by 3488
Keywords: multiple myeloma; early intervention; novel therapies; treatment approach; prognosis; bispecific antibodies; CAR T-cells
(This special issue belongs to the Section Oncology)
Applied Cardiorespiratory Physiology in Critical Care Medicine
edited by and Paraskevi Tselioti
submission deadline 25 Jul 2025 | 1 articles | Viewed by 3297
Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology
(This special issue belongs to the Section Anesthesiology)
Vasculitis in Adults and Children: Symptoms, Diagnosis and Treatment—2nd Edition
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 2329
Keywords: vasculitis; glucocorticoids; cyclophosphamide; molecularly targeted therapy; unmet clinical needs; potential therapeutic targets
(This special issue belongs to the Section Vascular Medicine)
Accelerating Fracture Healing: Clinical Diagnosis and Treatment
edited by Seong-Eun Byun
submission deadline 25 Jul 2025 | 3 articles | Viewed by 2087
Keywords: fracture; fracture surgery; fracture healing; diagnosis; treatment
(This special issue belongs to the Section Orthopedics)
Clinical Updates in Cardiac Electrophysiology: 2nd Edition
edited by Kenneth C. Bilchick
submission deadline 25 Jul 2025 | 1 articles | Viewed by 1790
Keywords: arrhythmias; atrial fibrillation; cardiac electrophysiology; heart rhythm disorders; ablation; ventricular tachycardia; remote monitoring; digital health; artificial intelligence; cardiac magnetic resonance
(This special issue belongs to the Section Cardiology)
Optimizing Present and Future Therapeutic Choices for Treatment and Management of Chronic Inflammatory Bowel Diseases—2nd Edition
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 1432
Keywords: Inflammatory Bowel Diseases(IBD); JAK inhibitors; mucosal healing
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
The Role of Biomarkers in Cardiovascular Diseases
edited by Giorgia Panichella
submission deadline 25 Jul 2025 | 2 articles | Viewed by 1258
Keywords: biomarkers; cardiovascular diseases; heart failure; ischemic heart disease; cardiomyopathy; risk stratification; diagnosis; prognosis; inflammation
(This special issue belongs to the Section Cardiovascular Medicine)
New Clinical Treatment for Ocular Vascular Disease and Fundus Disease: Second Edition
edited by , Shohista Saidkasimova and
submission deadline 25 Jul 2025 | 1 articles | Viewed by 884
Keywords: ocular vascular diseases; fundus disorders; diabetic retinopathy; retinal vein occlusion; age-related macular degeneration; retinal detachment
(This special issue belongs to the Section Ophthalmology)
Minimally Invasive Gynecological Surgery: State of the Art and the Perspectives
edited by Artur Jakimiuk
submission deadline 25 Jul 2025 | 1 articles | Viewed by 851
Keywords: robotic surgery; laparoscopy; hysteroscopy; gynecological oncolgy surgery; minimally invasive gynecological procedures; reproductive endocrinology; urinary incontinence; endometriosis; advance laparoscopic surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in the Field of Cutaneous Malignancies: Background and Clinical Management submission deadline 25 Jul 2025 | Viewed by 422
Keywords: dermatology; skin cancer; diagnosis; melanoma; basal cell carcinoma; squamous cell carcinoma; imaging; artificial intelligence; dermoscopy; treatment
(This special issue belongs to the Section Dermatology)
Clinical Advances in Genetic Obesity and Health submission deadline 25 Jul 2025 | Viewed by 373
Keywords: obesity; genetics; health; nutrigenetics; clinical trials; personalized
(This special issue belongs to the Section Endocrinology & Metabolism)
Innovations in Coronary Artery Disease Treatment and Prevention
edited by
submission deadline 25 Jul 2025 | Viewed by 201
Keywords: coronary artery disease (CAD); CAD prevention and treatment innovations; CAD biomarkers and imaging; advanced imaging and diagnostics; personalized medicine in cardiology; predictive analytics in CAD
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances in Hysteroscopic Technology for Gynecological Diseases
edited by Aya Mohr-Sasson and Raanan Meyer
submission deadline 25 Jul 2025 | Viewed by 180
Keywords: diagnostic hysteroscopy; operative hysteroscopy; uterine sampling; uterine polyp; submucosal fibroid; hysteroscopic dilatation and curettage; hysteroscopic niche repair
(This special issue belongs to the Section Obstetrics & Gynecology)
Robotic-Assisted Colorectal Surgery: Advancements and Clinical Applications submission deadline 25 Jul 2025 | Viewed by 173
Keywords: rectal cancer; diverticulitis; hemicolectomy; redo surgery; cost-effectiveness
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Gestational Diabetes: Cutting-Edge Research and Clinical Practice
edited by Vendula Bartakova
submission deadline 26 Jul 2025 | 6 articles | Viewed by 4247 | Submission Open
Keywords: gestational diabetes mellitus; oral glucose tolerance test; treatment; pregnancy; peripartal outcomes
(This special issue belongs to the Section Endocrinology & Metabolism)
Research Progress and Challenges in Acute Abdominal Surgery
edited by Matteo Cimino
submission deadline 26 Jul 2025 | 1 articles | Viewed by 1790 | Submission Open
Keywords: acute abdominal emergencies; urgent surgical interventions; minimally invasive techniques; robotic surgery in emergency surgery; open surgery; complications; pain management; postoperative rehabilitation; acute appendicitis; acute biliary disease; intraoperative ultrasonography in emergency surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiac Surgery: Innovations, Challenges and Opportunities
edited by Kyriakos Spiliopoulos and Keti Vitanova
submission deadline 28 Jul 2025 | 1 articles | Viewed by 683 | Submission Open
Keywords: minimally invasive cardiac surgery; redo cardiac surgery; transcatheter aortic valve implantation (TAVI); advances in mechanical circulatory support; endo-carditis; aortic surgery
(This special issue belongs to the Section Cardiology)
Peritoneal Dialysis—Procedure, Risks, Results submission deadline 28 Jul 2025 | Viewed by 275 | Submission Open
Keywords: peritoneal dialysis; peritoneal catheter placement; peritoneal dialysis outcomes; peritoneal membrane; peritoneal transport; infectious complications; mechanical complications; nutritional status; volume management; peritoneal dialysis solutions
(This special issue belongs to the Section Nephrology & Urology)
Clinical Challenges and Advances in Oncology Radiology
edited by Ammar A Chaudhry
submission deadline 28 Jul 2025 | Viewed by 159 | Submission Open
Keywords: radiomics; theranostics; oncology; targeted therapies; immuno-oncology
(This special issue belongs to the Section Oncology)
Shoulder and Elbow Surgery: Clinical Updates and Perspectives
edited by Taku Hatta, Akihiko Hasegawa and Takuma Yuri
submission deadline 28 Jul 2025 | Viewed by 154 | Submission Open
Keywords: rotator cuff injuries; shoulder arthroplasty; elbow surgery; shoulder surgery; shoulder and elbow disease; arthroscopic surgery; orthopedic surgery
(This special issue belongs to the Section Orthopedics)
Innovations in Neurorehabilitation
edited by
submission deadline 30 Jul 2025 | 8 articles | Viewed by 13853 | Submission Open
Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimulation; regenerative rehabilitation; neuroimaging; brain– computer interface; brain– spine interface; virtual reality; environmental control systems; higher level cognitive functions; vision rehabilitation
(This special issue belongs to the Section Clinical Rehabilitation)
Current Trends and Innovations in Arthroscopic Shoulder Surgery
edited by , Sebastian Siebenlist and Lucca Lacheta
submission deadline 30 Jul 2025 | 7 articles | Viewed by 12155 | Submission Open
Keywords: shoulder and adjacent joints; arthroscopic surgery; rotator cuff surgery; reconstructive shoulder surgery; minimally invasive surgery
(This special issue belongs to the Section Orthopedics)
Recent Advances in Acne, Rosacea and Hidradenitis Suppurativa
edited by and Alexandros Stratigos
submission deadline 30 Jul 2025 | 7 articles | Viewed by 10179 | Submission Open
Keywords: acne; rosacea; hidradenitis suppurativa; inflammatory skin diseases; papules; pustules; nodules; cysts; scars; topical medications; oral therapies; biological treatments; surgery; laser and light therapy; challenges; diagnosis; treatment; management; challenges
(This special issue belongs to the Section Dermatology)
Pediatric Pulmonology: Recent Developments and Emerging Trends
edited by Athina L. Papadopoulou
submission deadline 30 Jul 2025 | 4 articles | Viewed by 9910 | Submission Open
Keywords: definition of breath sounds; lung– gut axis pathophysiology; disease endotypes and phenotypes; asthma management in children; bronchiolitis spectrum; pediatric bronchopulmonary dysplasia; pulmonary function testing in pediatric patients; pediatric sleep-disordered breathing; neonatal respiratory distress syndrome; childhood interstitial lung diseases; pulmonary hypertension in children; biomarkers in pediatric lung diseases; allergy and the lungs; diagnostic and therapeutic challenges in bronchoscopy; gene therapy in cystic fibrosis
(This special issue belongs to the Section Clinical Pediatrics)
Sepsis: New Insights into Diagnosis and Treatment
edited by and Etrusca Brogi
submission deadline 30 Jul 2025 | 6 articles | Viewed by 9862 | Submission Open
Keywords: sepsis and sepsis subphenotypes; adjuvant therapy; blood purification strategies; immunomonitoring and immunotherapy; the microbiome in sepsis; crosstalk in multi-organ failure (MOF); ultrasound in sepsis (POCUS); sepsis-induced coagulophaty and DIC; antibiotic therapy; multimodal approaches to surgical source control
(This special issue belongs to the Section Infectious Diseases)
Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Recent Advances and Perspectives
edited by Ehud I. Assia
submission deadline 30 Jul 2025 | 8 articles | Viewed by 5936 | Submission Open
Keywords: premium IOLs (multifocal and toric); IOL power calculation; biometry and imaging; complications and management; laser vision correction; phakic IOLs; femtosecond-laser-assisted cataract surgery; AI (artificial intelligence) and cataract/refractive surgery; accommodative lenses
(This special issue belongs to the Section Ophthalmology)
New Insights into Joint Arthroplasty
edited by
submission deadline 30 Jul 2025 | 8 articles | Viewed by 5933 | Submission Open
Keywords: total hip arthroplasty; total knee arthroplasty; robotic-assisted technology and navigation; modern implant materials; modern implant fixation techniques; alignment in TKA; spinopelvic alignment in THA
(This special issue belongs to the Section Orthopedics)
Adult Congenital Heart Disease: Latest Advances and Prospects submission deadline 30 Jul 2025 | 3 articles | Viewed by 5654 | Submission Open
Keywords: adult congenital heart disease; heart failure; Fontan circulation; Tetralogy of Fallot; cathetherisation and structural interventions
(This special issue belongs to the Section Cardiology)
Transcatheter Aortic Valve Implantation and Replacement: Prospects and Challenges
edited by Konstantinos Toutouzas and
submission deadline 30 Jul 2025 | 3 articles | Viewed by 3745 | Submission Open
Keywords: TAVI; aortic stenosis; valve-in-valve; structural heart disease; TAVI-in-TAVI
(This special issue belongs to the Section Cardiology)
Oral Health in Children: Clinical Management submission deadline 30 Jul 2025 | 3 articles | Viewed by 3178 | Submission Open
Keywords: pediatric oral health; early childhood caries; preventive strategies; comprehensive clinical approach; early detection; oral care; minimal intervention dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Advances in Rehabilitation of Patients with Multiple Sclerosis (MS)
edited by
submission deadline 30 Jul 2025 | 3 articles | Viewed by 3155 | Submission Open
Keywords: multiple sclerosis; rehabilitation; virtual reality; telerehabilitation; quality of life
(This special issue belongs to the Section Clinical Neurology)
Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care submission deadline 30 Jul 2025 | 2 articles | Viewed by 2899 | Submission Open
Keywords: psycho-oncology; cancer care; adaptation process; illness experience; risk and protective factors; mental health care; oncofertility; palliative care; critical experience; prevention; qualitative and quantitative methods; quality of life; health behaviors
(This special issue belongs to the Section Mental Health)
Clinical Application of Radiotherapy in Modern Oncology submission deadline 30 Jul 2025 | 2 articles | Viewed by 2018 | Submission Open
Keywords: brain metastasis; bone metastasis; brain tumors; head and neck cancers; thoracic oncology; breast cancer; prostate cancer; sarcoma
(This special issue belongs to the Section Oncology)
Plastic Surgery: Challenges and Future Directions
edited by Philip Brazio and Edward C. Ray
submission deadline 30 Jul 2025 | 1 articles | Viewed by 1974 | Submission Open
Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
New Insights into Peritoneal Dialysis and Hemodialysis: 2nd Edition submission deadline 30 Jul 2025 | 1 articles | Viewed by 1156 | Submission Open
Keywords: hemodialysis; peritoneal dialysis; end-stage renal disease; kidney replacement therapy (KRT); pathophysiology; di-alysis membranes; dialysis preparation; dialysis modality; cardiovascular events; vascular access; PD-related perito-nitis; unfavorable adverse effects; complications; challenges; inflammation
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances of Glaucoma: Current Status and Prospects
edited by Rubén Sánchez-Jean, and Federico Sáenz-Francés San Baldomero
submission deadline 30 Jul 2025 | 1 articles | Viewed by 966 | Submission Open
Keywords: glaucoma surgery; new techniques; minimally invasive glaucoma surgery; intraocular pressure; optometry; IOLs designs
(This special issue belongs to the Section Ophthalmology)
Current Challenges and Advancements in Lateral Skull Base Surgery
edited by Alessia Rubini
submission deadline 30 Jul 2025 | 1 articles | Viewed by 921 | Submission Open
Keywords: lateral skull base; neurotology; jugular foramen; cerebellopontine angle; petrous apex; inner ear; acoustic neuroma; jugular paraganglioma; transtemporal approaches; infratemporal approaches
(This special issue belongs to the Section Otolaryngology)
Clinical Updates in Bleeding and Thrombotic Disorders
edited by
submission deadline 30 Jul 2025 | 1 articles | Viewed by 340 | Submission Open
Keywords: autoimmune-acquired coagulation deficiency; acquired hemophilia A; disseminated intravascular coagulation; thrombotic microangiopathy; venous thromboembolism; acute coronary syndrome; clot waveform analysis; thrombin generation test; thromboelastogram
(This special issue belongs to the Section Hematology)
Metabolic Dysregulation Across the Spectrum from Anorexia Nervosa to Obesity
edited by Andriana C. Kaliora
submission deadline 30 Jul 2025 | Viewed by 209 | Submission Open
Keywords: metabolic dysregulation; anorexia nervosa; obesity; environmental factors in metabolic health; gut microbiota and metabolism; hormonal regulation of appetite; inflammation and metabolic disorders; dietary influence on metabolism
(This special issue belongs to the Section Endocrinology & Metabolism)
Advances in the Treatment of Glaucoma and Ocular Hypertension
edited by Ahnul Ha
submission deadline 30 Jul 2025 | Viewed by 177 | Submission Open
Keywords: glaucoma; ocular hypertension; intraocular pressure (IOP); minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI); neuroprotection; meta-analysis
(This special issue belongs to the Section Ophthalmology)
Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss
edited by David Saceda-Corralo
submission deadline 31 Jul 2025 | 5 articles | Viewed by 20955 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss
(This special issue belongs to the Section Dermatology)
The Current Trend in the Management of Bruxism and Temporomandibular Disorders submission deadline 31 Jul 2025 | 5 articles | Viewed by 20329 | Submission Open
Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment
edited by
submission deadline 31 Jul 2025 | 10 articles | Viewed by 18709 | Submission Open
Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety
(This special issue belongs to the Section Immunology)
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