Non-Interventional Prospective Observational Study of Platelet Rich Fibrin as a Therapy Adjunctive in Patients with Medication-Related Osteonecrosis of the Jaw
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Setting
2.3. Participants
2.4. Variables, Data Sources/Measurement
2.5. Study Size
2.6. Statistical Analysis
3. Results
3.1. Participants
3.2. Descriptive Data
3.3. Outcome Data
3.4. Other Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Visit 1 (Screening) | Visit 2 (5th Day Post op.) | Visit 3 (14th Day Post op) | Visit 4 (42nd Day Post op.) | |
---|---|---|---|---|
Informed consent | X | |||
In-/exclusion criteria | X | X | ||
Demographic/baseline characteristics | X | |||
Staging according to AAOMS | X | X | X | X |
VAS | X | X | X | |
OHIP G14 | X | X | X | |
IPR | X | X | X | |
PWAT | X | X | X | |
discharge | X | |||
Suture removal | X | |||
resumption of antiresorptive therapy | X | |||
Adverse events | X | X | X | |
Medication | X | X | X | X |
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Blatt, S.; Krüger, M.; Kämmerer, P.W.; Thiem, D.G.E.; Matheis, P.; Eisenbeiß, A.-K.; Wiltfang, J.; Al-Nawas, B.; Naujokat, H. Non-Interventional Prospective Observational Study of Platelet Rich Fibrin as a Therapy Adjunctive in Patients with Medication-Related Osteonecrosis of the Jaw. J. Clin. Med. 2022, 11, 682. https://doi.org/10.3390/jcm11030682
Blatt S, Krüger M, Kämmerer PW, Thiem DGE, Matheis P, Eisenbeiß A-K, Wiltfang J, Al-Nawas B, Naujokat H. Non-Interventional Prospective Observational Study of Platelet Rich Fibrin as a Therapy Adjunctive in Patients with Medication-Related Osteonecrosis of the Jaw. Journal of Clinical Medicine. 2022; 11(3):682. https://doi.org/10.3390/jcm11030682
Chicago/Turabian StyleBlatt, Sebastian, Maximilian Krüger, Peer W. Kämmerer, Daniel G. E. Thiem, Philipp Matheis, Anne-Katrin Eisenbeiß, Jörg Wiltfang, Bilal Al-Nawas, and Hendrik Naujokat. 2022. "Non-Interventional Prospective Observational Study of Platelet Rich Fibrin as a Therapy Adjunctive in Patients with Medication-Related Osteonecrosis of the Jaw" Journal of Clinical Medicine 11, no. 3: 682. https://doi.org/10.3390/jcm11030682