The Efficacy of Mebeverine in the Treatment of Irritable Bowel Syndrome—A Systematic Review
, Ewa Malecka-Wojciesko 2, Barbara Skrzydlo-Radomanska 3 and Grazyna Rydzewska 4,5Round 1
Reviewer 1 Report
Authors state that "The risk of bias in experimental studies was assessed by the revised Cochrane risk-of-bias tool for randomized trials (RoB 2) [11]. The quality of observational studies was evaluated using the NICE checklist [12]". They may want to discuss about this in detail in Materials and Methods section.
Author Response
We thank you for drawing our attention to this aspect, as not all readers may be familiar with the tools we used. We supplemented our manuscript with essential information on the validity, assessment, and interpretation of the scales used, and highlighted in blue all the changes in the manuscript introduced since the last revision.
Reviewer 2 Report
The amendments have added further value to the review.
Author Response
We thank you for this positive comment. We are glad that the changes suggested by the reviewers allowed us to increase the value of our work.
