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Article

Does COVID-19 Infection within 1 Week after Total Knee Arthroplasty Affect Patients’ Early Clinical Outcomes? A Matched Case–Control Study

by
Jung-Kwon Bae
1,
Jae-Sung Seo
1,*,
Seong-Kee Shin
1,
Seo-Jin Kim
1 and
Jun-Ho Kim
2
1
Department of Orthopedic Surgery, Seoul Medical Center, Seoul 02053, Republic of Korea
2
Department of Orthopedic Surgery, Kyung Hee University Hospital at Gangdong, Seoul 05278, Republic of Korea
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2023, 12(13), 4496; https://doi.org/10.3390/jcm12134496
Submission received: 29 May 2023 / Revised: 25 June 2023 / Accepted: 3 July 2023 / Published: 5 July 2023
(This article belongs to the Special Issue Joint Arthroplasty: Current Status, Challenges, and Future Directions)
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Abstract

Recent studies have reported the impact of previous COVID-19 infection on the early clinical outcome after total knee arthroplasty (TKA). However, the timing of infection before the surgery was not constant and a study on patients with COVID-19 infection within 1 week after TKA is lacking. This study aimed to determine the effect of COVID-19 infection within one week after TKA on the postoperative outcomes and to compare the early clinical outcomes to those who were not infected with COVID-19 before and after surgery. No significant differences were observed between the two groups in terms of clinical outcomes or complications. The length of the hospital stay (LOS) was significantly longer for the COVID-19 group than for the non-COVID-19 group (p < 0.05). The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels were higher for the study group on postoperative days 9 and 12 than for those in the control group (p < 0.05). However, D-dimer levels were not significantly different between the two groups. We should cautiously consider that COVID-19 infection within 1 week after TKA may be associated with increased ESR, CRP levels, and length of hospital stay, but they are not associated with the worsening of early clinical outcomes or the occurrence of complications.
Keywords: COVID-19; knee; arthroplasty; outcomes; complications COVID-19; knee; arthroplasty; outcomes; complications

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MDPI and ACS Style

Bae, J.-K.; Seo, J.-S.; Shin, S.-K.; Kim, S.-J.; Kim, J.-H. Does COVID-19 Infection within 1 Week after Total Knee Arthroplasty Affect Patients’ Early Clinical Outcomes? A Matched Case–Control Study. J. Clin. Med. 2023, 12, 4496. https://doi.org/10.3390/jcm12134496

AMA Style

Bae J-K, Seo J-S, Shin S-K, Kim S-J, Kim J-H. Does COVID-19 Infection within 1 Week after Total Knee Arthroplasty Affect Patients’ Early Clinical Outcomes? A Matched Case–Control Study. Journal of Clinical Medicine. 2023; 12(13):4496. https://doi.org/10.3390/jcm12134496

Chicago/Turabian Style

Bae, Jung-Kwon, Jae-Sung Seo, Seong-Kee Shin, Seo-Jin Kim, and Jun-Ho Kim. 2023. "Does COVID-19 Infection within 1 Week after Total Knee Arthroplasty Affect Patients’ Early Clinical Outcomes? A Matched Case–Control Study" Journal of Clinical Medicine 12, no. 13: 4496. https://doi.org/10.3390/jcm12134496

APA Style

Bae, J.-K., Seo, J.-S., Shin, S.-K., Kim, S.-J., & Kim, J.-H. (2023). Does COVID-19 Infection within 1 Week after Total Knee Arthroplasty Affect Patients’ Early Clinical Outcomes? A Matched Case–Control Study. Journal of Clinical Medicine, 12(13), 4496. https://doi.org/10.3390/jcm12134496

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