Ultrasound-Guided Needle Biopsy as an Alternative to Chamberlain’s Mediastinotomy and Video-Assisted Thoracoscopic Surgery (VATS) in the Diagnosis of Anterior Mediastinal Neoformations: A Retrospective Analysis
Abstract
:1. Introduction
2. Materials and Methods
- Accuracy =
- diagnostic procedures/performed procedures
- Sensitivity =
- true positives/(true positives + false negatives)
- Specificity =
- true negatives/(false negatives + true negatives)
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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<40 Years Old (n, %) | ≥40 Years Old (n, %) | Total (n, %) | |
---|---|---|---|
Males (n, %) | 20 (24.1) | 21 (25.3) | 41 (49.4) |
Females (n, %) | 20 (24.1) | 22 (26.5) | 42 (50.6) |
Total (n, %) | 40 (48.2) | 43 (51.8) | 83 (100.0) |
Needle Size | Collected Frustules (n, %) | ||||||
---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | >5 | Total | |
12G | 3 (13.6) | 7 (31.8) | 10 (45.5) | 1 (4.5) | 0 (0.0) | 1 (4.5) | 22 (100.0) |
14G | 1 (10.0) | 1 (10.0) | 4 (40.0) | 3 (30.0) | 1 (10.0) | 0 (0.0) | 10 (100.0) |
16G | 3 (6.4) | 3 (6.4) | 16 (34.0) | 15 (31.9) | 6 (12.8) | 4 (8.5) | 47 (100.0) |
18G | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (66.6) | 1 (33.3) | 0 (0.0) | 3 (100.0) |
Total | 7 (8.4) | 11 (14.5) | 29 (34.9) | 21 (25.3) | 8 (9.6) | 5 (6.0) | 82 (100.0) * |
Final Diagnosis | Males | Females | Total | ||
---|---|---|---|---|---|
<40 y (n, %) | ≥40 y (n, %) | <40 y (n, %) | ≥40 y (n, %) | ||
Non-Hodgkin’s lymphoma | 13 (15.7) | 3 (3.6) | 8 (9.6) | 8 (9.6) | 32 (38.6) |
Hodgkin’s lymphoma | 4 (4.8) | 2 (2.4) | 10 (12.0) | 5 (6.0) | 21 (25.3) |
Thymoma | 0 (0.0) | 5 (6.0) | 0 (0.0) | 4 (4.8) | 9 (10.8) |
Neuroendocrine tumors | 0 (0.0) | 4 (4.8) | 0 (0.0) | 0 (0.0) | 4 (4.8) |
Germ cell tumors | 2 (2.4) | 1 (1.2) | 0 (0.0) | 0 (0.0) | 3 (3.6) |
Thyroid cancer | 0 (0.0) | 1 (1.2) | 0 (0.0) | 0 (0.0) | 1 (1.2) |
Other | 0 (0.0) | 5 (6.0) | 0 (0.0) | 3 (3.6) | 8 (9.6) |
Undiagnosed | 1 (1.2) | 0 (0.0) | 2 (2.4) | 2 (2.4) | 5 (6.0) |
Total | 20 (24.1) | 21 (25.3) | 20 (24.1) | 22 (26.5) | 83 (100.0) |
Reference | Country | Study Design | Sample Size (n) | Accuracy (%) | Sensitivity (%) | Specificity (%) | Complications (%) |
---|---|---|---|---|---|---|---|
Chen et al., 2014 [22] | China | Retrospective | 80 | 89 | 71 | 84 | Major complications: 0 |
Minor complications: NR | |||||||
Huang et al., 2019 [19] | China | Retrospective | 121 | 95 | 94 | 100 | Major complications: 0 |
(10 AMMs) | Minor complications: 4 | ||||||
Petkov et al., 2020 [18] | Bulgaria | Retrospective | 308 | 96 | 95 | 100 | Overall complications: 2.6 |
(283 AMMs) | |||||||
Navin et al., 2021 [23] | USA | Retrospective | 337 | 96 | - | - | Major complications: 0.3 |
(303 AMMs) | Minor complications: 2 | ||||||
Vischia et al., 2023 | Italy | Retrospective | 83 | 94 | 94 | 100 | Major complications: 0 |
Minor complications: 2.4 |
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Vischia, F.; Di Maio, G.; Ferrero, S.A.I.; Rolfo, E.; Scaglione, L.; Cristofori, R.; Ruffini, E.; Lorenzati, B.; Landi, A.; Novero, D.; et al. Ultrasound-Guided Needle Biopsy as an Alternative to Chamberlain’s Mediastinotomy and Video-Assisted Thoracoscopic Surgery (VATS) in the Diagnosis of Anterior Mediastinal Neoformations: A Retrospective Analysis. J. Clin. Med. 2023, 12, 5070. https://doi.org/10.3390/jcm12155070
Vischia F, Di Maio G, Ferrero SAI, Rolfo E, Scaglione L, Cristofori R, Ruffini E, Lorenzati B, Landi A, Novero D, et al. Ultrasound-Guided Needle Biopsy as an Alternative to Chamberlain’s Mediastinotomy and Video-Assisted Thoracoscopic Surgery (VATS) in the Diagnosis of Anterior Mediastinal Neoformations: A Retrospective Analysis. Journal of Clinical Medicine. 2023; 12(15):5070. https://doi.org/10.3390/jcm12155070
Chicago/Turabian StyleVischia, Federico, Giacomo Di Maio, Simona A. I. Ferrero, Elio Rolfo, Luca Scaglione, Riccardo Cristofori, Enrico Ruffini, Bartolomeo Lorenzati, Andrea Landi, Domenico Novero, and et al. 2023. "Ultrasound-Guided Needle Biopsy as an Alternative to Chamberlain’s Mediastinotomy and Video-Assisted Thoracoscopic Surgery (VATS) in the Diagnosis of Anterior Mediastinal Neoformations: A Retrospective Analysis" Journal of Clinical Medicine 12, no. 15: 5070. https://doi.org/10.3390/jcm12155070