Group A Streptococcus Infection in Neonatal Population: A Systematic Review of The Literature
Abstract
:1. Introduction
2. Materials and Methods
2.1. Search Protocol/Databases
2.2. Exclusion Criteria
- Studies that included neonates in the same group as children and adult patients and did not provide specific data regarding the neonatal population.
- Systematic reviews, meta-analyses, as well as studies coming from conference proceedings and those limited only to an abstract.
2.3. Study Outcome(s)
- Risk factors/characteristics of the affected neonates.
- Clinical presentation of GAS infection in neonates.
- Outcome of the neonates with GAS infection including mortality.
2.4. Data Synthesis and Presentation
2.5. Disagreement Resolution
3. Results
3.1. Study Selection
3.2. Study Characteristics
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Reported Data | Missing Data | ||
---|---|---|---|
Gestational age (weeks) | Preterm | 30/43 (69.8) | 151/194 (77.8) |
Term | 13/43 (30.2) | ||
Gender | Male | 35/59 (59.3) | 135/194 (69.6) |
Female | 24/59 (40.7) | ||
Delivery mode | Vaginal | 17/26 (65.4) | 168/194 (86.6) |
Cesarean section | 9/26 (34.6) |
EOS | LOS | |
---|---|---|
Respiratory distress | 12/20 (60) | 7/49 (14.2) |
Fever | 6/20 (30) | 15/49 (30.6) |
Rash | 6/19 (30) | 23/49 (46.9) |
Gastrointestinal disturbances | 4/20 (20) | 22/49 (44.9) |
All Cases (n = 194) | EOS (n = 20) | LOS (n = 49) | |
---|---|---|---|
Meningitis | 10 | - | 5 |
Pneumonia (empyema) | 5 (4) | 5 (3) | - |
Omphalitis | 18 | - | - |
Peritonitis | 9 | - | 8 |
Skin lesions | 5 | - | 1 |
Osteomyelitis/arthritis | 2 | - | 2 |
TSS | 5 | 4 | 1 |
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Sokou, R.; Filippatos, F.; Daniil, V.; Bikouli, E.-D.; Tsantes, A.G.; Piovani, D.; Bonovas, S.; Iliodromiti, Z.; Boutsikou, T.; Tsantes, A.E.; et al. Group A Streptococcus Infection in Neonatal Population: A Systematic Review of The Literature. J. Clin. Med. 2023, 12, 6974. https://doi.org/10.3390/jcm12226974
Sokou R, Filippatos F, Daniil V, Bikouli E-D, Tsantes AG, Piovani D, Bonovas S, Iliodromiti Z, Boutsikou T, Tsantes AE, et al. Group A Streptococcus Infection in Neonatal Population: A Systematic Review of The Literature. Journal of Clinical Medicine. 2023; 12(22):6974. https://doi.org/10.3390/jcm12226974
Chicago/Turabian StyleSokou, Rozeta, Filippos Filippatos, Vasiliki Daniil, Efstathia-Danai Bikouli, Andreas G. Tsantes, Daniele Piovani, Stefanos Bonovas, Zoi Iliodromiti, Theodora Boutsikou, Argirios E. Tsantes, and et al. 2023. "Group A Streptococcus Infection in Neonatal Population: A Systematic Review of The Literature" Journal of Clinical Medicine 12, no. 22: 6974. https://doi.org/10.3390/jcm12226974