Clinical Outcomes of Conservative Surgery for Diffuse Uterine Leiomyomatosis: Preliminary Experience of 17 Cases in a Single Center
Abstract
:1. Introduction
2. Materials and Methods
Surgical Technique
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Mean age (years) | 36.12 (29–48, SD = 5.4) |
Previous myomectomy | |
Laparotomic | 6 (35.3%) |
Laparoscopic | 6 (35.3%) |
Hysteroscopic | 2 (11.8%) |
None | 3 (17.6%) |
Marital status | |
No | 8 (47.1%) |
Yes | 9 (52.9%) |
Abortion | |
No | 4/9 (44.4%) |
Yes | 5/9 (55.6%) |
Main symptom | |
Menorrhagia a | 16 (94.1%) |
Dysmenorrhea b | 0 |
Combined | 1 (5.9%) |
Operation time (minute) | 97.06 (70–160, SD = 22.71) |
EBL (mL) | 283.53 (20–1000, SD = 273.72) |
Weight of excised specimen (gram) | 345.41 (89–910, SD = 240.65) |
Intraoperative transfusion (N = 17) | |
No | 16 (94.1%) |
Yes | 1 (5.9%) |
Hb 2 week before operation | 12.32 (10–14.9, SD = 1.57) |
Hb 1 day after operation | 9.64 (7.2–13.1, SD = 1.85) |
Hospital stay (day) | 6.47 (6–8, SD = 0.62) |
Mean follow-up duration (weeks) | 116.41 (32–216, SD = 50.88) |
Relief of symptoms recurrence a | 100% |
No | 12 (70.6%) |
Yes | 5 (29.4%) |
Recurrence-free interval (weeks) | 50.6 (27–87, SD = 23.71) |
Medication for recurrence (N = 5) | |
No | 4 (80%) |
Yes | 1 (20%) |
Reoperation | 0 (0%) |
Case | Reference | Study | Enrolled Number | Symptoms | Treatment | Outcome |
---|---|---|---|---|---|---|
1 | Jieun Koh et al. [20] | Retrospective | 7 | Menorrhagia | Uterine artery embolization | Symptom relief |
2 | Li Chen et al. [33] | Case report | 1 | Menorrhagia Dysmenorrhea | High intensity focused ultrasound | Symptom control |
3 | Xiaofei Zhang et al. [34] | Research article | 8 | Menorrhagia Dysmenorrhea | High intensity focused ultrasound | Uterine volume shrinkage |
4 | Luigi Fedele et al. [35] | Descriptive study | 3 | Menorrhagia | Myomectomy | Menstrual pattern, pregnancy |
5 | Yasuo Otsubo et al. [5] | Case report | 1 | infertility | Myomectomy | Pregnancy |
6 | Masato Nishida et al. [19] | Original article | 7 | Menorrhagia | Myomectomy | Anemia improved. Pregnancy |
7 | Christian Scheurig et al. [18] | Case report | 6 | Menorrhagia Dysmenorrhea | Uterine artery embolization | Alleviation of symptoms |
8 | Aki Kido et al. [36] | Case report | 1 | Hypermenorrhea Dysmenorrhea | Uterine artery embolization | Reduced volume |
9 | Sudhir Kunchala et al. [37] | Case report | 1 | Menorrhagia Dysmenorrhea | Uterine artery embolization | Resolution of symptoms |
10 | Yuji Hiramatsu et al. [38] | Case report | 3 | Menorrhagia | Myomectomy | |
11 | Ikuo Konishi et al. [39] | Case report | 1 | Menorrhagia Dysmenorrhea Infertility | Myomectomy | Pregnancy |
12 | Sojung Kweon et al. (this work) | Original article | 17 | Menorrhagia Dysmenorrhea | Myomectomy | Symptoms relief Reduced volume |
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Kweon, S.; Park, J.; Sim, Y.; Kwack, J.Y.; Kwon, Y.-S. Clinical Outcomes of Conservative Surgery for Diffuse Uterine Leiomyomatosis: Preliminary Experience of 17 Cases in a Single Center. J. Clin. Med. 2023, 12, 7638. https://doi.org/10.3390/jcm12247638
Kweon S, Park J, Sim Y, Kwack JY, Kwon Y-S. Clinical Outcomes of Conservative Surgery for Diffuse Uterine Leiomyomatosis: Preliminary Experience of 17 Cases in a Single Center. Journal of Clinical Medicine. 2023; 12(24):7638. https://doi.org/10.3390/jcm12247638
Chicago/Turabian StyleKweon, Sojung, Joowon Park, Youngseo Sim, Jae Young Kwack, and Yong-Soon Kwon. 2023. "Clinical Outcomes of Conservative Surgery for Diffuse Uterine Leiomyomatosis: Preliminary Experience of 17 Cases in a Single Center" Journal of Clinical Medicine 12, no. 24: 7638. https://doi.org/10.3390/jcm12247638