Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review
Round 1
Reviewer 1 Report
This is a clinically relevant topic.
The manuscript needs extensive editing by a native English speaker.
The authors have discussed the various TS, possible pathophysiology. A table mentioning the various drugs causing these syndromes could be added .Also some mention about functional MRI studies would be worthwhile.
Author Response
the manuscript underwent english corrections
table of drug agents provoking Tardive syndrome wsa added
f MRI in Tardive dyskinesia was added
table 1
Table 1
|
Neuroleptic agents Anticholinergic agents SSRI antidepressants as fluoxetine and sertraline Other antidepressants as trazadone, clomipramine, amitriptyline MAOI Lithium Antiemetics as metoclopramide, prochlorperazine Anticonvulsants as carbamazepine and lamotrigine Antihistamine as hydroxyzine Anxiolytics as GABA agonist and barbiturates Antimalarial as chloroquine |
Medications associated with tardive dyskinesia
Author Response File: 
Author Response.docx
Reviewer 2 Report
The authors' attempts are good, but there is very little content.
The rationale for the classification of Tardive Syndrome is poor. The description of each symptom is also poor. There is also too little information on treatment, and not enough on surgical treatment such as DBS.
Author Response
i made english corrections
the rational information was improved
more inormation on treatment
Author Response File: Author Response.docx
Round 2
Reviewer 2 Report
The description of treatment is still scant. In particular, botulinum treatment and surgical treatment need to be added.
Author Response
hello sir
- I checked the references and were added several
- My revision was marked up using TRACK CHANGES
- I am the the last version to the journal and to you
- I hope that i completed your notes
- Sincerely yours samih badarny
Author Response File: Author Response.docx
