Arterial Elastance: A Predictor of Hypotension Due to Anesthesia Induction
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethical Approval
2.2. Patients
2.3. Study Protocol
2.4. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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The number of the patients, n (%) | 85 (100.0) |
Age, years | 63 (52–68) |
Male, n (%) | 63 (74.1) |
BMI (kg/m2) | 26.1 (23.5–29.3) |
ASA score | 2 (2–2) |
Comorbidities, n (%) | |
Hypertension | 45 (52.9) |
Diabetes mellitus | 30 (35.3) |
Coronary arterial disease | 17 (20.0) |
COPD | 7 (8.2) |
Cardiac failure | 3 (3.5) |
Cerebrovascular event | 2 (2.4) |
Chronic renal failure | 2 (2.4) |
Preoperative period | |
The usage of beta-blockers | 14 (16.5) |
The usage of ACE/AR blockers | 3 (3.5) |
The usage of laxatives | 50 (58.8) |
Fasting, hours | 10 (10–12) |
Pre-Induction | Post-Induction | p | |
---|---|---|---|
SAP (mmHg) | 144 ± 22 | 107 ± 24 | <0.001 |
DAP (mmHg) | 72 (64–77) | 56 (50–66) | <0.001 |
MAP (mmHg) | 96 (86–105) | 72 (62–85) | <0.001 |
Ea (mmHg m−2mL−1) | 1.0 (0.8–1.1) | 1.1 (0.9–1.3) | 0.028 |
SVV (%) | 13 ± 4 | 12 ± 5 | 0.034 |
PPV (%) | 11 (9–14) | 12 (9–17) | 0.112 |
CI (L/min/m2) | 3.2 (2.8–4.1) | 2.4 (2.0–2.8) | <0.001 |
CPO (watt) | 1.3 (1.1–1.8) | 0.8 (0.6–1.0) | <0.001 |
Dp/Dt (mmHg/msn) | 1.4 (1.1–1.8) | 0.8 (0.6–1.0) | <0.001 |
HR (bpm) | 72 (66–82) | 69 (62–80) | 0.018 |
Hypotension (−) (n = 53) | Hypotension (+) (n = 32) | p | |
---|---|---|---|
Age, years | 64 (53–68) | 62 (51–68) | 0.438 |
Male, n (%) | 42 (79.2) | 21 (65.6) | 0.165 |
BMI (kg/m2) | 26.1 (23.6–31.0) | 25.3 (23.2–28.0) | 0.425 |
ASA | 2 (2–2) | 2 (2–2) | 0.118 |
Comorbidities, n (%) | |||
Hypertension | 29 (54.7) | 16 (50.0) | 0.673 |
Diabetes mellitus | 18 (34.0) | 12 (37.5) | 0.741 |
Coronary arterial disease | 13 (24.5) | 4 (12.5) | 0.095 |
COPD | 4 (7.5) | 3 (9.4) | 1 |
Cardiac failure | 2 (3.8) | 1 (3.1) | 1 |
Cerebrovascular event | 2 (3.8) | 0 (0.0) | 0.525 |
Chronic renal failure | 2 (3.8) | 0 (0.0) | 0.525 |
Preoperative period | |||
The usage of beta-blockers | 9 (17.0) | 5 (15.6) | 1 |
The usage of ACE/AR blockers | 1 (0.0) | 2 (6.3) | 0.554 |
The usage of laxatives | 32 (60.4) | 18 (56.3) | 0.708 |
Fasting, hours | 10 (10–12) | 12 (10–12) | 0.075 |
Administered IV fluid, mL | 150 (100–150) | 150 (100–188) | 0.596 |
Pre-induction parameters | |||
SAP (mmHg) | 147 ± 21 | 141 ± 24 | 0.196 |
DAP (mmHg) | 70 ± 9 | 71 ± 9 | 0.568 |
MAP (mmHg) | 95 ± 12 | 94 ± 13 | 0.585 |
Ea (mmHg m−2mL−1) | 0.9 ± 0.2 | 1.2 ± 0.3 | <0.001 |
SVV (%) | 12 ± 3 | 14 ± 5 | 0.036 |
PPV (%) | 11 (9–14) | 12 (10–14) | 0.284 |
CI (L/min/m2) | 3.2 (2.8–4.1) | 3.1 (2.7–3.9) | 0.267 |
CPO (watt) | 1.4 (1.1–1.9) | 1.2 (1.0–1.5) | 0.078 |
Dp/Dt (mmHg/msn) | 1.4 (1.2–1.9) | 1.2 (1.0–1.7) | 0.094 |
HR (bpm) | 69 (66–79) | 79 (67–85) | 0.055 |
Post-induction parameters | |||
SAP (mmHg) | 117 (108–134) | 84 (75–90) | <0.001 |
DAP (mmHg) | 63 ± 9 | 50 ± 5 | <0.001 |
MAP (mmHg) | 82 ± 12 | 61 ± 6 | <0.001 |
Ea (mmHg m−2mL−1) | 1.0 (0.9–1.3) | 1.1 (0.9–1.2) | 0.96 |
SVV (%) | 11 ± 4 | 13 ± 5 | 0.148 |
PPV (%) | 12 (8–15) | 14 (10–20) | 0.036 |
CI (L/min/m2) | 2.5 (2.1–3.0) | 2.1 (1.9–2.5) | <0.001 |
CPO (watt) | 0.9 (0.8–1.1) | 0.5 (0.5–0.7) | <0.001 |
Dp/Dt (mmHg/msn) | 0.9 (0.8–1.1) | 0.6 (0.5–0.8) | <0.001 |
HR (bpm) | 71 ± 12 | 71 ± 14 | 0.821 |
Administered ephedrine, mg | 0 (0–0) | 10 (1–15) | <0.001 |
OR (95% CI) | p | |
---|---|---|
Ea ≥ 1.08 mmHg m−2mL−1 | 3.5 (1.4–9.1) | 0.009 |
SVV ≥ %13 | 1.5 (0.6–4.0) | 0.398 |
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Aktas Yildirim, S.; Sarikaya, Z.T.; Dogan, L.; Ulugol, H.; Gucyetmez, B.; Toraman, F. Arterial Elastance: A Predictor of Hypotension Due to Anesthesia Induction. J. Clin. Med. 2023, 12, 3155. https://doi.org/10.3390/jcm12093155
Aktas Yildirim S, Sarikaya ZT, Dogan L, Ulugol H, Gucyetmez B, Toraman F. Arterial Elastance: A Predictor of Hypotension Due to Anesthesia Induction. Journal of Clinical Medicine. 2023; 12(9):3155. https://doi.org/10.3390/jcm12093155
Chicago/Turabian StyleAktas Yildirim, Serap, Zeynep Tugce Sarikaya, Lerzan Dogan, Halim Ulugol, Bulent Gucyetmez, and Fevzi Toraman. 2023. "Arterial Elastance: A Predictor of Hypotension Due to Anesthesia Induction" Journal of Clinical Medicine 12, no. 9: 3155. https://doi.org/10.3390/jcm12093155