Next Article in Journal
Neurofilament Light Chain as Biomarker in Encephalitis
Previous Article in Journal
Phenotype and Treatment Options for Mesenteric Lymph Node Cavitating Syndrome in Coeliac Disease: A Case Series and Literature Review
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

Renal Outcome in Patients Undergoing Minimally Invasive Total Coronary Revascularization via Anterior Minithoracotomy Compared to Full Median Sternotomy Coronary Artery Bypass Grafting

by
Christian Sellin
1,*,
Sarah Laube
2,
Volodymyr Demianenko
1,
Robert Balan
3,
Hilmar Dörge
1 and
Peter Benoehr
4
1
Department of Cardiothoracic Surgery, Klinikum Fulda gAG, University Medicine Marburg, Campus Fulda, 36043 Fulda, Germany
2
Department of Anaesthesiology, Klinikum Fulda gAG, University Medicine Marburg, Campus Fulda, 36043 Fulda, Germany
3
Department of Cardiac Surgery, Klinikum Passau, 94036 Passau, Germany
4
Department of Nephrology, Klinikum Fulda gAG, University Medicine Marburg, Campus Fulda, 36043 Fulda, Germany
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(18), 5418; https://doi.org/10.3390/jcm13185418
Submission received: 1 August 2024 / Revised: 30 August 2024 / Accepted: 11 September 2024 / Published: 12 September 2024

Abstract

: Objective: Renal dysfunction and acute renal failure after coronary artery bypass grafting (CABG) are among the main causes of increased mortality and morbidity. A sternum-sparing concept of minimally invasive total coronary revascularization via anterior minithoracotomy (TCRAT) was introduced with promising early and midterm outcomes in multivessel coronary artery disease. There are limited data regarding renal complications in patients undergoing the TCRAT technique. The present study analyzed renal outcomes in TCRAT compared to CABG via full median sternotomy (FS). Methods: We analyzed the records of 227 consecutive TCRAT patients (from September 2021 to June 2023) and 228 consecutive FS patients (from January 2017 to December 2018) who underwent nonemergent CABG. Following propensity score matching, preoperative baseline characteristics—including age, sex, diabetes mellitus, arterial hypertension, left ventricular ejection fraction, EuroSCORE II, preoperative serum creatinine, estimated glomerular filtration rate (eGFR), serum urea, and pre-existing chronic renal insufficiency—were comparable between the TCRAT (n = 170) and the FS group (n = 170). The examined postoperative renal parameters and complications were serum creatinine, eGFR, and serum urea on the first postoperative day. Moreover, serum creatinine, eGFR and serum urea at the time of discharge, postoperative ARF, and hemodialysis were investigated. Additionally, the duration of operation, CPB time, aortic cross-clamp time, ICU and hospital stay, ECMO support, rethoracotomy and in-hospital mortality were analyzed. The parameters were compared between groups using a Student’s t-test or Mann–Whitney U test. Results: The duration of operation (332 ± 66 vs. 257 ± 61 min; p < 0.05), CPB time (161 ± 40 vs. 116 ± 38 min; p < 0.05), and aortic cross-clamp time (100 ± 31 vs. 76 ± 26; p < 0.05) were longer in the TCRAT group. ICU (1.8 ± 2.2 vs. 2.9 ± 3.6 days; p < 0.05) and hospital (10.4 ± 7.6 vs. 12.4 ± 7.5 days; p < 0.05) stays were shorter in the TCRAT group. There were no differences between groups with regard to the renal parameters examined. Conclusion: Despite a prolonged duration of operation, CPB time, and aortic cross-clamp time when using the TCRAT technique, no increase in renal complications were found. In addition, ICU and hospital stays in the TCRAT group were shorter compared to CABG via full median sternotomy.
Keywords: minimally invasive cardiac surgery; coronary artery bypass grafting; CABG; acute renal failure; TCRAT minimally invasive cardiac surgery; coronary artery bypass grafting; CABG; acute renal failure; TCRAT

Share and Cite

MDPI and ACS Style

Sellin, C.; Laube, S.; Demianenko, V.; Balan, R.; Dörge, H.; Benoehr, P. Renal Outcome in Patients Undergoing Minimally Invasive Total Coronary Revascularization via Anterior Minithoracotomy Compared to Full Median Sternotomy Coronary Artery Bypass Grafting. J. Clin. Med. 2024, 13, 5418. https://doi.org/10.3390/jcm13185418

AMA Style

Sellin C, Laube S, Demianenko V, Balan R, Dörge H, Benoehr P. Renal Outcome in Patients Undergoing Minimally Invasive Total Coronary Revascularization via Anterior Minithoracotomy Compared to Full Median Sternotomy Coronary Artery Bypass Grafting. Journal of Clinical Medicine. 2024; 13(18):5418. https://doi.org/10.3390/jcm13185418

Chicago/Turabian Style

Sellin, Christian, Sarah Laube, Volodymyr Demianenko, Robert Balan, Hilmar Dörge, and Peter Benoehr. 2024. "Renal Outcome in Patients Undergoing Minimally Invasive Total Coronary Revascularization via Anterior Minithoracotomy Compared to Full Median Sternotomy Coronary Artery Bypass Grafting" Journal of Clinical Medicine 13, no. 18: 5418. https://doi.org/10.3390/jcm13185418

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop