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Review

Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy and Cardiac Amyloidosis: From Clinical Management to Catheter Ablation Indication

by
Raffaella Mistrulli
*,
Armando Ferrera
,
Melwyn Luis Muthukkattil
,
Allegra Battistoni
,
Giovanna Gallo
,
Emanuele Barbato
,
Francesco Raffaele Spera
and
Damiano Magrì
Clinical and Molecular Medicine Department, Sapienza University of Rome, 00185 Rome, Italy
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(2), 501; https://doi.org/10.3390/jcm13020501
Submission received: 6 November 2023 / Revised: 11 January 2024 / Accepted: 15 January 2024 / Published: 16 January 2024

Abstract

Atrial fibrillation (AF) is the most common arrhythmia in patients affected by cardiomyopathies. Reports estimate a prevalence of 27% in patients with hypertrophic cardiomyopathy (HCM) and 40% in patients with cardiac amyloidosis (CA). The presence of AF typically results in progressive functional decline, an increased frequency of hospitalizations for heart failure, and a higher thromboembolic risk. Medical management using mainly beta-blockers or amiodarone has produced variable outcomes and a high rate of recurrence. Catheter ablation reduces symptom burden and complications despite a moderate rate of recurrence. Recent evidence suggests that an early rhythm control strategy may lead to more favorable short- and long-term outcomes. In this review, we summarize contemporary data on the management of AF in patients with cardiomyopathy (HCM and CA) with particular reference to the timing and outcomes of ablation procedures.
Keywords: atrial fibrillation; hypertrophic cardiomyopathy; cardiac amyloidosis; catheter ablatio atrial fibrillation; hypertrophic cardiomyopathy; cardiac amyloidosis; catheter ablatio

Share and Cite

MDPI and ACS Style

Mistrulli, R.; Ferrera, A.; Muthukkattil, M.L.; Battistoni, A.; Gallo, G.; Barbato, E.; Spera, F.R.; Magrì, D. Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy and Cardiac Amyloidosis: From Clinical Management to Catheter Ablation Indication. J. Clin. Med. 2024, 13, 501. https://doi.org/10.3390/jcm13020501

AMA Style

Mistrulli R, Ferrera A, Muthukkattil ML, Battistoni A, Gallo G, Barbato E, Spera FR, Magrì D. Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy and Cardiac Amyloidosis: From Clinical Management to Catheter Ablation Indication. Journal of Clinical Medicine. 2024; 13(2):501. https://doi.org/10.3390/jcm13020501

Chicago/Turabian Style

Mistrulli, Raffaella, Armando Ferrera, Melwyn Luis Muthukkattil, Allegra Battistoni, Giovanna Gallo, Emanuele Barbato, Francesco Raffaele Spera, and Damiano Magrì. 2024. "Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy and Cardiac Amyloidosis: From Clinical Management to Catheter Ablation Indication" Journal of Clinical Medicine 13, no. 2: 501. https://doi.org/10.3390/jcm13020501

APA Style

Mistrulli, R., Ferrera, A., Muthukkattil, M. L., Battistoni, A., Gallo, G., Barbato, E., Spera, F. R., & Magrì, D. (2024). Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy and Cardiac Amyloidosis: From Clinical Management to Catheter Ablation Indication. Journal of Clinical Medicine, 13(2), 501. https://doi.org/10.3390/jcm13020501

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