Paper-Based Screen-Printed Ionic-Liquid/Graphene Electrode Integrated with Prussian Blue/MXene Nanocomposites Enabled Electrochemical Detection for Glucose Sensing
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals and Materials
2.2. Apparatus
2.3. Fabrication of Screen-Printed IL/Graphene Electrodes (SPIL-GEs) on Paper Based
2.4. Preparation of Modified PB/Ti3C2Tx/GOx/Nafion on Paper-Based Screen-Printed Ionic Liquid/Graphene Electrode (SPIL-GE) Glucose Sensor
2.5. Fabrication of the Paper-Based Glucose Sensor
2.6. Real Sample Analysis and Interference Studies
3. Results and Discussions
3.1. Electrochemical Characterization of the Modified Electrodes
3.2. The Topographical Analysis of Ti3C2Tx and PB/Ti3C2Tx
3.3. Selection the Optimal Concentration of PB/Ti3C2Tx Modified on Paper-Based SPIL-GE
3.4. Selection the Optimal Detection Potential of PB/Ti3C2Tx/Gox/Nafion/SPIL-GE
3.5. Analytical Performance of Glucose Determination on PB/Ti3C2Tx/Gox/Nafion/SPIL-GE
3.6. Real Sample Analysis of the Paper-Based PB/Ti3C2Tx/Gox/Nafion/SPIL-GE and Interferences Study
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Samples | Paper-Based PB/Ti3C2Tx/Gox/Nafion/SPIL-GE (mM ± sd) | Automated Analyzer (Hexokinase Method) (mM) |
---|---|---|
1 | 4.46 ± 0.36 | 4.67 |
2 | 8.23 ± 1.14 | 8.00 |
3 | 12.64 ± 1.04 | 12.61 |
4 | 4.31 ± 0.51 | 4.28 |
5 | 7.07 ± 0.63 | 7.67 |
6 | 12.36 ± 0.59 | 12.50 |
7 | 6.40 ± 1.46 | 6.22 |
8 | 9.92 ± 1.17 | 9.61 |
9 | 9.57 ± 0.38 | 10.22 |
10 | 10.32 ± 0.59 | 10.06 |
Sensor * | Technique | LOD | Analytical Range | Reference |
---|---|---|---|---|
GOx/AuNP/PANI/rGO/NH2-MWCNTs modified SPCE | Chronoamperometry | 0.064 mM | 1–10 mM | [35] |
GA@PB/SPCE GA@PB/SPCE | Chronoamperometry | 0.15 mM | 0.5–6 mM | [36] |
p-taurine/GOx/Nf-modified GCE | Differential pulse voltammetry | 0.06 mM | 0.9–15 mM | [37] |
Nafion/GOx/SiIONPs/SPCEs | Chronoamperometry | 0.22 mM | Up to 3 mM | [38] |
The paper-based PB/Ti3C2Tx/GOx/Nafion/SPIL-GE | Chronoamperometry | 0.024 mM | 0.08–15 mM | Present work |
Test Substances | % Recovery |
---|---|
Glucose 5 mM | 100 |
Glucose 5 mM + Uric Acid (0.1 mM) | 91.1 |
Glucose 5 mM + Ascorbic Acid (0.1 mM) | 97.3 |
Glucose 5 mM + Hemoglobin (0.06 mM) | 93.2 |
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Niamsi, W.; Larpant, N.; Kalambate, P.K.; Primpray, V.; Karuwan, C.; Rodthongkum, N.; Laiwattanapaisal, W. Paper-Based Screen-Printed Ionic-Liquid/Graphene Electrode Integrated with Prussian Blue/MXene Nanocomposites Enabled Electrochemical Detection for Glucose Sensing. Biosensors 2022, 12, 852. https://doi.org/10.3390/bios12100852
Niamsi W, Larpant N, Kalambate PK, Primpray V, Karuwan C, Rodthongkum N, Laiwattanapaisal W. Paper-Based Screen-Printed Ionic-Liquid/Graphene Electrode Integrated with Prussian Blue/MXene Nanocomposites Enabled Electrochemical Detection for Glucose Sensing. Biosensors. 2022; 12(10):852. https://doi.org/10.3390/bios12100852
Chicago/Turabian StyleNiamsi, Wisanu, Nutcha Larpant, Pramod K. Kalambate, Vitsarut Primpray, Chanpen Karuwan, Nadnudda Rodthongkum, and Wanida Laiwattanapaisal. 2022. "Paper-Based Screen-Printed Ionic-Liquid/Graphene Electrode Integrated with Prussian Blue/MXene Nanocomposites Enabled Electrochemical Detection for Glucose Sensing" Biosensors 12, no. 10: 852. https://doi.org/10.3390/bios12100852