Green and Chemical Silver Nanoparticles and Pomegranate Formulations to Heal Infected Wounds in Diabetic Rats
Abstract
:1. Introduction
2. Results
2.1. Wound Healing Activity
2.2. CFU Determination from Ulcers
2.3. Quantitative Image Evaluation for Inflammatory Infiltrate, Angiogenesis, and Fibroplasia
2.4. Dosage of Enzyme Myeloperoxidase (MPO)
2.5. Collagen Evaluation
3. Discussion
4. Materials and Methods
4.1. Spray Formulations
4.2. Ethics Statement
4.3. In Vivo Models for Wound Healing Activity
4.4. Wound Healing Activity
4.5. Material Collection for Future Studies
4.6. CFU Determination from Ulcers
4.7. Quantitative Image Evaluation of Inflammatory Infiltrate, Angiogenesis, and Fibroplasia
4.8. Dosage of Myeloperoxidase Enzyme (MPO)
4.9. Evaluation of Collagen Levels
4.10. Statistical Analyses
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Scappaticci, R.A.F.; Berretta, A.A.; Torres, E.C.; Buszinski, A.F.M.; Fernandes, G.L.; dos Reis, T.F.; de Souza-Neto, F.N.; Gorup, L.F.; de Camargo, E.R.; Barbosa, D.B. Green and Chemical Silver Nanoparticles and Pomegranate Formulations to Heal Infected Wounds in Diabetic Rats. Antibiotics 2021, 10, 1343. https://doi.org/10.3390/antibiotics10111343
Scappaticci RAF, Berretta AA, Torres EC, Buszinski AFM, Fernandes GL, dos Reis TF, de Souza-Neto FN, Gorup LF, de Camargo ER, Barbosa DB. Green and Chemical Silver Nanoparticles and Pomegranate Formulations to Heal Infected Wounds in Diabetic Rats. Antibiotics. 2021; 10(11):1343. https://doi.org/10.3390/antibiotics10111343
Chicago/Turabian StyleScappaticci, Renan Aparecido Fernandes, Andresa Aparecida Berretta, Elina Cassia Torres, Andrei Felipe Moreira Buszinski, Gabriela Lopes Fernandes, Thaila Fernanda dos Reis, Francisco Nunes de Souza-Neto, Luiz Fernando Gorup, Emerson Rodrigues de Camargo, and Debora Barros Barbosa. 2021. "Green and Chemical Silver Nanoparticles and Pomegranate Formulations to Heal Infected Wounds in Diabetic Rats" Antibiotics 10, no. 11: 1343. https://doi.org/10.3390/antibiotics10111343