Trend of Bioactive Molecules and Biomaterial Coating in Promoting Tendon—Bone Healing
Round 1
Reviewer 1 Report
In this manuscript (coatings-1764717), the authors have provided the review based on the trend of bioactive molecules and biomaterials coating to promote tendon-bone healing. This review is interesting and timely and can be considered for publication after a revision. The content of the review is appropriately reviewed and discussed, but the presentation quality is lacking.
1. Please check the figure numbers in the manuscript carefully.
2. In addition to Figs, 1 and 5, the authors should provide the 5-6 representative figures from the literature, which are discussed in this review for a clear understanding of the readers.
3. It would be great and imperative to prepare figures 1 and 5 in the manuscript by the authors for better information and presentation. In their current state, these figures are not having sufficient efficacy in this manuscript.
Author Response
Dear Editor and Reviewers,
Thangks very much for taking your time to review this manuscript.I really appreciate all cooments and suggestions ！Please find my itemized responses in below and my revisions in the submitted files.Thanks again!
Suggestion 1 response: I have checked the figure numbers in correct order.
Suggestion 2 response: I have added two representative figures for a clear understanding of readers.
Suggestion 3 response: I made a detailed description for the two figtures.
Author Response File: 
Author Response.docx
Reviewer 2 Report
1. Type of the manuscript should be changed to “Review”, not “Article”. See line 1.
2. In the tittle “trend” should be changed to “Trend”.
3. Please reorder keywords in alphabetical order.
4. Several review articles have been published related to coatings in tendon healing. May the authors explain their significant and something really new deliver in the present review? It should be highlighted.
5. Suggested literature published by MDPI needs to be adopted in the present article as follows: Computational Contact Pressure Prediction of CoCrMo, SS 316L and Ti6Al4V Femoral Head against UHMWPE Acetabular Cup under Gait Cycle. J. Funct. Biomater. 2022, 13, 64. https://doi.org/10.3390/jfb13020064
6. Basic concept of bone healing needs further explanation.
7. Several complication due to biocompatible problems in the effort of Tendon-bone needs more discussion.
8. Additional illustration is needed to make the reader more interested and easier to understand.
9. Limitation of the present review should be explained.
10. Conclusion is too long, please making it more concise.
11. Further studies should be stated.
12. I am not impressive on the present review due to very small substance. It should be extend to be more enrich content.
13. There are several grammatical error and mismatch English style in the present form, please revise the English used. MDPI English service may be an alternative to the authors.
14. Please recheck the MDPI format used to avoid typesetting errors.
15. Overall, the present review article is still poor, the authors need serious improvement after revision.
Author Response
Dear Editor and Reviewes,
Thanks very much for taking your time to review this munuscript . I really appreciate all coments and suggestions ! Please find my itemized responses in below and my revisions in submitted files , Thanks again!
Suggesion 1 response: I have changed the type.
Suggesion 2 response: I have revised.
Suggesion 3 response: I have revised.
Suggesion 4 response: I have add two articles about tendon healing and discussed.
Suggession 5 response: I have revised the review according to adviced article.
Suggession 6 response: I have made further explanation about concept of bone healing.
Suggession 7 response： I have made some discussion about biocompatible problems.
Suggession 8 response: I made some detailed explanation about figures and add more two figures.
Suggession 9 response: I have revised.
Suggession 10 response: I have make the conclusion more concise.
Suggession 11 response: I have stated futher studies.
Suggession 12 response: I have made the content enrichment.
Suggession 13 response: I had professional native English speaker polish it.
Suggession 14 response: I have rechecked.
Suggession 15 response: Thanks very much for taking your time to review this munuscripr .I really appreciate all coments and suggestions.
Round 2
Reviewer 1 Report
In my opinion, this manuscript can now be accepted for publication.
Author Response
Dear Editor and Reviewes,
Thanks very much for taking your time to review this munuscript . I really appreciate all coments and suggestions !
Author Response File: Author Response.docx
Reviewer 2 Report
Appreciate the authors for their effort in revising the manuscript after peer review. I take the time to read their response to my previous review report and revised manuscript. However, their response did not appropriately address my comments, especially in numbers 1, 4, 5, 6, 7, 8, 9, 10, 12, 14, and 15. The way of authors to response my previous comments also does not match what they did on the revised manuscript. Overall, this manuscript is lack quality and does not bring a serious scientific contribution. With all due respect, this manuscript should be rejected and not published. Thank you.
Author Response
ear Editor and Reviewes,
Thanks very much for taking your time to review this munuscript . I really appreciate all coments and suggestions !
1、Question 1:Type of the manuscript should be changed to “Review”, not “Article”. See line 1.
Response: Thanks very much for your suggestion.I have changed “Article”into “Review”.See line 1 marked in yellow font.
2、Question 4: Several review articles have been published related to coatings in tendon healing. May the authors explain their significant and something really new deliver in the present review? It should be highlighted.
Response: Thanks very much for your suggestion.I have revised. See line 488 to 491 marked in yellow font.
3、Question 5: Suggested literature published by MDPI needs to be adopted in the present article as follows: Computational Contact Pressure Prediction of CoCrMo, SS 316L and Ti6Al4V Femoral Head against UHMWPE Acetabular Cup under Gait Cycle. J. Funct. Biomater. 2022, 13, 64. https://doi.org/10.3390/jfb13020064
Response: Thanks very much for your suggestion.I have revised. See line 387 to 489 marked in yellow font.
4、Question 6: Basic concept of bone healing needs further explanation.
Response: Thanks very much for your suggestion.I have revised. See line 67 to 69 and line 107 to 113 marked in yellow font.
5、Question 7: Several complication due to biocompatible problems in the effort of Tendon-bone needs more discussion.
Response: Thanks very much for your suggestion.I have revised. See line 384 to 390 marked in yellow font.
6、Question 8: Additional illustration is needed to make the reader more interested and easier to understand.
Response: Thanks very much for your suggestion.I have revised. See line 150 to 167 and line 233 to 249 marked in yellow font.
7、Question 9: Limitation of the present review should be explained.
Response: Thanks very much for your suggestion.I have revised. See line 510 to 516 marked in yellow font.
8、Question 10: Conclusion is too long, please making it more concise.
Response: Thanks very much for your suggestion.I have revised. See line 489 to 511 marked in yellow font.
9、Question 12: I am not impressive on the present review due to very small substance. It should be extend to be more enrich content.
Response: Thanks very much for your suggestion.I have revised. See line 150 to 167, line 233 to 249, line 318 to 321 and line 483 to 486 marked in yellow font.
10、Question 14: Please recheck the MDPI format used to avoid typesetting errors.
Response:Thanks very much for your suggestion.I have revised.
11、Question 15: Overall, the present review article is still poor, the authors need serious improvement after revision.
Response:Thanks very much for your suggestion. I have made additional illustration and made futher explanation and enriched the content of each part of the article.
Author Response File: Author Response.docx
