2009 March - 5 articles
Detailed insights into the pathobiochemical mechanisms of the inflammatory process and the molecular actions of anti-inflammatory drugs are determinants for successful intervention with inflammatory diseases. Gender differences regarding susceptibili...
Chlamydia pneumoniae is a common bacterium causing respiratory tract infections worldwide. Usually the outcome is mild upper respiratory tract infection but also pneumonia is detected. Persistent C. pneumoniae infection has been connected to differen...
About 22% of the “druggable” human genome codes target protein kinases. However, only 8 registered drugs worldwide address protein kinase targets (e. g. Gleevec®, Iressa®). Kinases regulate many different signaling processes. Devastating diseases suc...
Strategies for inhibiting gene expression have been applied in several therapeutic applications Indeed, administration of nucleic acids such as antisense oligonucleotides (AS-ODNs) or small interfering RNA (siRNA) has raised a lot of interests in the...
Proteins play a fundamental role in controlling multiple functions within a cell s organization. At pathologic conditions, specifically expressed proteins may indicate disease states and may thus serve as diagnostic markers. Following disease-associa...
Get Alerted
Add your email address to receive forthcoming issues of this journal.
