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Conference Report

Compartmental Modelling of the Pharmacokinetics of an Efflux Transporter

by
T. R. B. GRANDJEAN
1,
J. T. W. YATES
2 and
M. J. CHAPPELL
1,*
1
School of Engineering, Warwick University, Coventry, United Kingdom
2
AstraZeneca R&D, Alderley Park, Cheshire, United Kingdom
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2010, 78(3), 727-728; https://doi.org/10.3797/scipharm.cespt.8.POT12
Submission received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010

Abstract

A mathematical model has been developed describing the pharmacokinetics of Hoechst 33342 following administration into a culture medium containing a population of transfected cells (HEK293 hBCRP) with a potent inhibitor of the BCRP, Fumitremorgin C (FTC), present. [...]

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MDPI and ACS Style

GRANDJEAN, T.R.B.; YATES, J.T.W.; CHAPPELL, M.J. Compartmental Modelling of the Pharmacokinetics of an Efflux Transporter. Sci. Pharm. 2010, 78, 727-728. https://doi.org/10.3797/scipharm.cespt.8.POT12

AMA Style

GRANDJEAN TRB, YATES JTW, CHAPPELL MJ. Compartmental Modelling of the Pharmacokinetics of an Efflux Transporter. Scientia Pharmaceutica. 2010; 78(3):727-728. https://doi.org/10.3797/scipharm.cespt.8.POT12

Chicago/Turabian Style

GRANDJEAN, T. R. B., J. T. W. YATES, and M. J. CHAPPELL. 2010. "Compartmental Modelling of the Pharmacokinetics of an Efflux Transporter" Scientia Pharmaceutica 78, no. 3: 727-728. https://doi.org/10.3797/scipharm.cespt.8.POT12

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