Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans
Abstract
:1. Introduction
2. Results
3. Discussion
4. Materials and Methods
4.1. Animals
4.2. Diets
4.3. Free Wheel Running
4.4. Behavior
4.5. Gene Expression Analysis
4.6. Metabolic Cages
4.7. Body Composition
4.8. Glucose Tolerance Test
4.9. Human Exercise Study
4.10. Measurement of Metabolites in Plasma
4.11. Statistical Analysis
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Valente-Silva, P.; Cervenka, I.; Ferreira, D.M.S.; Correia, J.C.; Edman, S.; Horwath, O.; Heng, B.; Chow, S.; Jacobs, K.R.; Guillemin, G.J.; et al. Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans. Metabolites 2021, 11, 508. https://doi.org/10.3390/metabo11080508
Valente-Silva P, Cervenka I, Ferreira DMS, Correia JC, Edman S, Horwath O, Heng B, Chow S, Jacobs KR, Guillemin GJ, et al. Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans. Metabolites. 2021; 11(8):508. https://doi.org/10.3390/metabo11080508
Chicago/Turabian StyleValente-Silva, Paula, Igor Cervenka, Duarte M. S. Ferreira, Jorge C. Correia, Sebastian Edman, Oscar Horwath, Benjamin Heng, Sharron Chow, Kelly R. Jacobs, Gilles J. Guillemin, and et al. 2021. "Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans" Metabolites 11, no. 8: 508. https://doi.org/10.3390/metabo11080508