Cardiometabolic and Cellular Adaptations to Multiple vs. Single Daily HIIT Sessions in Wistar Rats: Impact of Short-Term Detraining
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals and Study Design
2.2. Test to Determine VO2max
2.3. Training and Detraining Protocols
2.4. Body Composition Analysis
2.5. Heart Rate and Systolic Blood Pressure Records
2.6. Resting Oxygen Consumption Records
2.7. Oral Glucose Tolerance Test (OGTT)
2.8. Intraperitoneal Insulin Tolerance Test (IpITT)
2.9. Euthanasia
2.10. Heart Function Records
2.11. Histological Analyses
2.12. Mitochondrial Density Analyses
2.13. Statistical Analysis
3. Results
3.1. Training and Detraining Effects of 1xHIIT and 3xHIIT on VO2max, Body Mass and Food Intake
3.2. Training and Detraining Effects of 1xHIIT and 3xHIIT on Body Composition
3.3. Training and Detraining Effects of 1xHIIT and 3xHIIT on Resting Oxygen Consumption and Blood Glucose Homeostasis
3.4. Training and Detraining Effects of 1xHIIT and 3xHIIT on Cardiovascular Parameters
3.5. Training and Detraining Effects of 1xHIIT and 3xHIIT on Mitochondrial Densities of Cardiac and Skeletal Muscles
4. Discussion
4.1. Cardiovascular System
4.2. Metabolic System
4.3. Body Composition
4.4. Study Limitations and Future Directions
4.5. Practical Implications
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Costa-Pereira, L.V.; Mendes, B.F.; Magalhães, C.O.D.; Rodrigues, C.M.; de Andrade, J.A.; de Pereira, R.R.S.; Esteves, E.A.; Cassilhas, R.C.; Andrade, E.F.; Gripp, F.; et al. Cardiometabolic and Cellular Adaptations to Multiple vs. Single Daily HIIT Sessions in Wistar Rats: Impact of Short-Term Detraining. Metabolites 2024, 14, 447. https://doi.org/10.3390/metabo14080447
Costa-Pereira LV, Mendes BF, Magalhães COD, Rodrigues CM, de Andrade JA, de Pereira RRS, Esteves EA, Cassilhas RC, Andrade EF, Gripp F, et al. Cardiometabolic and Cellular Adaptations to Multiple vs. Single Daily HIIT Sessions in Wistar Rats: Impact of Short-Term Detraining. Metabolites. 2024; 14(8):447. https://doi.org/10.3390/metabo14080447
Chicago/Turabian StyleCosta-Pereira, Liliane Vanessa, Bruno Ferreira Mendes, Caíque Olegário Diniz Magalhães, Cíntia Maria Rodrigues, Júllia Alves de Andrade, Ramona Ramalho Souza de Pereira, Elizabethe Adriana Esteves, Ricardo Cardoso Cassilhas, Eric Francelino Andrade, Fernando Gripp, and et al. 2024. "Cardiometabolic and Cellular Adaptations to Multiple vs. Single Daily HIIT Sessions in Wistar Rats: Impact of Short-Term Detraining" Metabolites 14, no. 8: 447. https://doi.org/10.3390/metabo14080447