Biological Materials for Tissue-Engineered Vascular Grafts: Overview of Recent Advancements

Di Francesco, Dalila; Pigliafreddo, Alexa; Casarella, Simona; Di Nunno, Luca; Mantovani, Diego; Boccafoschi, Francesca

doi:10.3390/biom13091389

Open AccessReview

Biological Materials for Tissue-Engineered Vascular Grafts: Overview of Recent Advancements

by

Dalila Di Francesco

^1,2,†,

Alexa Pigliafreddo

^1,†,

Simona Casarella

¹,

Luca Di Nunno

¹,

Diego Mantovani

²

and

Francesca Boccafoschi

^1,*

¹

Department of Health Sciences, University of Piemonte Orientale “A. Avogadro”, 28100 Novara, Italy

²

Laboratory for Biomaterials and Bioengineering, CRC-I, Department of Min-Met-Materials Engineering, University Hospital Research Center, Regenerative Medicine, Laval University, Quebec City, QC G1V 0A6, Canada

^*

Author to whom correspondence should be addressed.

^†

These authors contributed equally to this work.

Biomolecules 2023, 13(9), 1389; https://doi.org/10.3390/biom13091389

Submission received: 25 August 2023 / Revised: 11 September 2023 / Accepted: 12 September 2023 / Published: 14 September 2023

(This article belongs to the Section Bio-Engineered Materials)

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Abstract

The clinical demand for tissue-engineered vascular grafts is still rising, and there are many challenges that need to be overcome, in particular, to obtain functional small-diameter grafts. The many advances made in cell culture, biomaterials, manufacturing techniques, and tissue engineering methods have led to various promising solutions for vascular graft production, with available options able to recapitulate both biological and mechanical properties of native blood vessels. Due to the rising interest in materials with bioactive potentials, materials from natural sources have also recently gained more attention for vascular tissue engineering, and new strategies have been developed to solve the disadvantages related to their use. In this review, the progress made in tissue-engineered vascular graft production is discussed. We highlight, in particular, the use of natural materials as scaffolds for vascular tissue engineering.

Keywords: vascular tissue engineering; natural biomaterials; tissue-engineered vascular grafts

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MDPI and ACS Style

Di Francesco, D.; Pigliafreddo, A.; Casarella, S.; Di Nunno, L.; Mantovani, D.; Boccafoschi, F. Biological Materials for Tissue-Engineered Vascular Grafts: Overview of Recent Advancements. Biomolecules 2023, 13, 1389. https://doi.org/10.3390/biom13091389

AMA Style

Di Francesco D, Pigliafreddo A, Casarella S, Di Nunno L, Mantovani D, Boccafoschi F. Biological Materials for Tissue-Engineered Vascular Grafts: Overview of Recent Advancements. Biomolecules. 2023; 13(9):1389. https://doi.org/10.3390/biom13091389

Chicago/Turabian Style

Di Francesco, Dalila, Alexa Pigliafreddo, Simona Casarella, Luca Di Nunno, Diego Mantovani, and Francesca Boccafoschi. 2023. "Biological Materials for Tissue-Engineered Vascular Grafts: Overview of Recent Advancements" Biomolecules 13, no. 9: 1389. https://doi.org/10.3390/biom13091389

APA Style

Di Francesco, D., Pigliafreddo, A., Casarella, S., Di Nunno, L., Mantovani, D., & Boccafoschi, F. (2023). Biological Materials for Tissue-Engineered Vascular Grafts: Overview of Recent Advancements. Biomolecules, 13(9), 1389. https://doi.org/10.3390/biom13091389

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

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Biological Materials for Tissue-Engineered Vascular Grafts: Overview of Recent Advancements

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