Immunohistochemical and Ultrastructural Characterization of Telocytes in Normal and Diabetic Human Kidneys
Abstract
:1. Introduction
2. Materials and Methods
2.1. Light Microscopy
2.2. Transmission Electron Microscopy
2.3. Statistical Analysis
3. Results
3.1. Immunophenotype and Localization of Telocytes in Normal and Diabetic Human Kidney Tissues
3.2. Ultrastructure of Telocytes in Normal and Diabetic Human Kidney Tissues
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Glomerulus | Tubule-Interstitium | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Bowman’s Capsule | Mesangial Cells | Glomerular Endothelial Cells | Peritubular Capillaries | Tubules | Interstitium | |||||||
Antibodies | N | D | N | D | N | D | N | D | N | D | N | D |
CD34 | + | + | - | + | ++ | ++ | ++ | ++ | + | + | + | + |
Nestin | + | + | ++ | + | ++ | + | +/- | + | + | + | +/- | +/- |
α-SMA | ++ | ++ | + | + | +/- | +/- | + | ++ | + | ++ | ++ | ++ |
Vimentin | ++ | ++ | + | + | ++ | ++ | + | ++ | + | ++ | + | ++ |
c-Kit | +/- | - | - | - | - | - | - | - | +/- | +/- | - | - |
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Valente, S.; Villacampa Lahoz, M.; Vasuri, F.; Pasquinelli, G. Immunohistochemical and Ultrastructural Characterization of Telocytes in Normal and Diabetic Human Kidneys. Biomolecules 2024, 14, 968. https://doi.org/10.3390/biom14080968
Valente S, Villacampa Lahoz M, Vasuri F, Pasquinelli G. Immunohistochemical and Ultrastructural Characterization of Telocytes in Normal and Diabetic Human Kidneys. Biomolecules. 2024; 14(8):968. https://doi.org/10.3390/biom14080968
Chicago/Turabian StyleValente, Sabrina, Marta Villacampa Lahoz, Francesco Vasuri, and Gianandrea Pasquinelli. 2024. "Immunohistochemical and Ultrastructural Characterization of Telocytes in Normal and Diabetic Human Kidneys" Biomolecules 14, no. 8: 968. https://doi.org/10.3390/biom14080968