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Volume 14
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10.3390/biom14091101
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Review

Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies

by
Wenkai Jiang
1,†,
Xiao Li
1,†,
Yi Zhang
2 and
Wence Zhou
1,*
1
The Second Clinical Medical College, Lanzhou University, Lanzhou 730030, China
2
The First Clinical Medical College, Lanzhou University, Lanzhou 730030, China
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Biomolecules 2024, 14(9), 1101; https://doi.org/10.3390/biom14091101
Submission received: 28 June 2024 / Revised: 11 August 2024 / Accepted: 30 August 2024 / Published: 2 September 2024
(This article belongs to the Section Natural and Bio-derived Molecules)
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Abstract

Acute pancreatitis remains a serious public health problem, and the burden of acute pancreatitis is increasing. With significant morbidity and serious complications, appropriate and effective therapies are critical. Great progress has been made in understanding the pathophysiology of acute pancreatitis over the past two decades. However, specific drugs targeting key molecules and pathways involved in acute pancreatitis still require further study. Natural compounds extracted from plants have a variety of biological activities and can inhibit inflammation and oxidative stress in acute pancreatitis by blocking several signaling pathways, such as the nuclear factor kappa-B and mitogen-activated protein kinase pathways. In this article, we review the therapeutic effects of various types of phytochemicals on acute pancreatitis and discuss the mechanism of action of these natural compounds in acute pancreatitis, aiming to provide clearer insights into the treatment of acute pancreatitis.
Keywords: acute pancreatitis; anti-inflammation; MAPK; NF-κB; phytochemical acute pancreatitis; anti-inflammation; MAPK; NF-κB; phytochemical

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MDPI and ACS Style

Jiang, W.; Li, X.; Zhang, Y.; Zhou, W. Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies. Biomolecules 2024, 14, 1101. https://doi.org/10.3390/biom14091101

AMA Style

Jiang W, Li X, Zhang Y, Zhou W. Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies. Biomolecules. 2024; 14(9):1101. https://doi.org/10.3390/biom14091101

Chicago/Turabian Style

Jiang, Wenkai, Xiao Li, Yi Zhang, and Wence Zhou. 2024. "Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies" Biomolecules 14, no. 9: 1101. https://doi.org/10.3390/biom14091101

APA Style

Jiang, W., Li, X., Zhang, Y., & Zhou, W. (2024). Natural Compounds for the Treatment of Acute Pancreatitis: Novel Anti-Inflammatory Therapies. Biomolecules, 14(9), 1101. https://doi.org/10.3390/biom14091101

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