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Biomolecules
Volume 8
Issue 3
10.3390/biom8030080
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Review

Research Progress on the Relationship between Atherosclerosis and Inflammation

by
Yuhua Zhu
†,
Xuemei Xian
†,
Zhenzhen Wang
,
Yingchao Bi
,
Quangang Chen
,
Xufeng Han
,
Daoquan Tang
and
Renjin Chen
*
Laboratory Animal Center, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to the work.
Biomolecules 2018, 8(3), 80; https://doi.org/10.3390/biom8030080
Submission received: 14 June 2018 / Revised: 3 August 2018 / Accepted: 17 August 2018 / Published: 23 August 2018
Versions Notes

Abstract

Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture, vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute cardiovascular disease. Atherosclerosis-related inflammation is mediated by proinflammatory cytokines, inflammatory signaling pathways, bioactive lipids, and adhesion molecules. This review discusses the effects of inflammation and the systemic inflammatory signaling pathway on atherosclerosis, the role of related signaling pathways in inflammation, the formation of atherosclerosis plaques, and the prospects of treating atherosclerosis by inhibiting inflammation.
Keywords: atherosclerosis; inflammation; anti-inflammatory therapy atherosclerosis; inflammation; anti-inflammatory therapy

Share and Cite

MDPI and ACS Style

Zhu, Y.; Xian, X.; Wang, Z.; Bi, Y.; Chen, Q.; Han, X.; Tang, D.; Chen, R. Research Progress on the Relationship between Atherosclerosis and Inflammation. Biomolecules 2018, 8, 80. https://doi.org/10.3390/biom8030080

AMA Style

Zhu Y, Xian X, Wang Z, Bi Y, Chen Q, Han X, Tang D, Chen R. Research Progress on the Relationship between Atherosclerosis and Inflammation. Biomolecules. 2018; 8(3):80. https://doi.org/10.3390/biom8030080

Chicago/Turabian Style

Zhu, Yuhua, Xuemei Xian, Zhenzhen Wang, Yingchao Bi, Quangang Chen, Xufeng Han, Daoquan Tang, and Renjin Chen. 2018. "Research Progress on the Relationship between Atherosclerosis and Inflammation" Biomolecules 8, no. 3: 80. https://doi.org/10.3390/biom8030080

APA Style

Zhu, Y., Xian, X., Wang, Z., Bi, Y., Chen, Q., Han, X., Tang, D., & Chen, R. (2018). Research Progress on the Relationship between Atherosclerosis and Inflammation. Biomolecules, 8(3), 80. https://doi.org/10.3390/biom8030080

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