Incidence of Post-Traumatic Stress Disorder after Coronavirus Disease
Abstract
:1. Introduction
2. Methods
2.1. Patients
2.2. Laboratory Procedures
2.3. Treatment Methods
2.4. Evaluation of PTSD
2.5. PCL-5
2.6. Statistical Analysis
3. Results
3.1. Characteristics of Patients with COVID-19
3.2. Differences in the Demographic Characteristics of COVID-19 Patients in the PTSD and Non-PTSD Groups
4. Discussion
Author Contributions
Funding
Conflicts of Interest
References
- Chang, M.C.; Lee, W.; Hur, J.; Park, D. Chest Computed Tomography Findings in Asymptomatic Patients with COVID-19. Respiration 2020, 2020, 1–7. [Google Scholar] [CrossRef]
- Chang, M.C.; Baek, J.H.; Park, D. Lessons from South Korea Regarding the Early Stage of the COVID-19 Outbreak. Healthcare 2020, 8, 229. [Google Scholar] [CrossRef] [PubMed]
- Burki, T. The Origin of SARS-CoV-2. Lancet Infect. Dis. 2020, 20, 1018–1019. [Google Scholar] [CrossRef]
- Andersen, K.G.; Rambaut, A.; Lipkin, W.I.; Holmes, E.C.; Garry, R.F. The Proximal Origin of SARS-CoV-2. Nat. Med. 2020, 26, 450–452. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Cucinotta, D.; Vanelli, M. WHO Declares COVID-19 a Pandemic. Acta Bio-Med. 2020, 91, 157–160. [Google Scholar]
- Chang, M.C.; Seo, W.-S.; Park, D.; Hur, J. Analysis of SARS-CoV-2 Screening Clinic (Including Drive-through System) Data at a Single University Hospital in South Korea from 27 January 2020 to 31 March 2020 during the COVID-19 Outbreak. Healthcare 2020, 8, 145. [Google Scholar] [CrossRef]
- Chang, M.C.; Hur, J.; Park, D. Strategies for the Prevention of the Intra-Hospital Transmission of COVID-19: A Retrospective Cohort Study. Healthcare 2020, 8, 195. [Google Scholar] [CrossRef]
- Hwang, J.-M.; Kim, J.-H.; Park, J.-S.; Chang, M.C.; Park, D. Neurological Diseases as Mortality Predictive Factors for Patients with COVID-19: A Retrospective Cohort Study. Neurol. Sci. 2020, 2020, 1–8. [Google Scholar] [CrossRef]
- Wang, L.-S.; Wang, Y.-R.; Ye, D.-W.; Liu, Q. Review of the 2019 Novel Coronavirus (SARS-CoV-2) Based on Current Evidence. Int. J. Antimicrob. Agents 2020, 55, 105948. [Google Scholar] [CrossRef]
- Chang, M.C.; Hwang, J.-M.; Jeon, J.-H.; Kwak, S.G.; Park, D.; Moon, J.S. Fasting Plasma Glucose Level Independently Predicts the Mortality of Patients with Coronavirus Disease 2019 Infection: A Multicenter, Retrospective Cohort Study. Endocrinol. Metab. 2020, 35, 595–601. [Google Scholar] [CrossRef]
- Sieńko, J.; Kotowski, M.; Bogacz, A.; Lechowicz, K.; Drożdżal, S.; Rosik, J.; Sietnicki, M.; Sieńko, M.; Kotfis, K. COVID-19: The Influence of ACE Genotype and ACE-I and ARBs on the Course of SARS-CoV-2 Infection in Elderly Patients. Clin. Interv. Aging 2020, 15, 1231–1240. [Google Scholar] [CrossRef] [PubMed]
- Río, J.M.-D.; Piqueras-Flores, J.; De La Sierra, P.N.-S.M.; Negreira-Caamaño, M.; Águila-Gordo, D.; Mateo-Gómez, C.; Salas-Bravo, D.; Rodríguez-Martínez, M. Comparative Analysis Between the Use of Renin-Angiotensin System Antagonists and Clinical Outcomes of Hospitalized Patients with COVID-19 Respiratory Infection. Med. Clínica 2020. [Google Scholar] [CrossRef]
- Liu, Y.; Mao, B.; Liang, S.; Yang, J.-W.; Lu, H.-W.; Chai, Y.-H.; Wang, L.; Zhang, L.; Li, Q.-H.; Zhao, L.; et al. Association Between Age and Clinical Characteristics and Outcomes of COVID-19. Eur. Respir. J. 2020, 55, 2001112. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Hau, Y.S.; Kim, J.K.; Hur, J.; Chang, M.C. How About Actively Using Telemedicine during the COVID-19 pandemic? J. Med. Syst. 2020, 44, 108. [Google Scholar] [CrossRef] [PubMed]
- Kucharski, A.J.; Russell, T.W.; Diamond, C.; Liu, Y.; Edmunds, J.; Funk, S.; Eggo, R.M.; Sun, F.; Jit, M.; Munday, J.D.; et al. Early Dynamics of Transmission and Control of COVID-19: A Mathematical Modelling Study. Lancet Infect. Dis. 2020, 20, 553–558. [Google Scholar] [CrossRef] [Green Version]
- Miao, X.; Chen, Q.-B.; Wei, K.; Tao, K.-M.; Lu, Z. Posttraumatic Stress Disorder: From Diagnosis to Prevention. Mil. Med. Res. 2018, 5, 32. [Google Scholar] [CrossRef]
- Lusk, J.D.; Sadeh, N.; Wolf, E.J.; Miller, M.W. Reckless Self-Destructive Behavior and PTSD in Veterans: The Mediating Role of New Adverse Events. J. Trauma. Stress 2017, 30, 270–278. [Google Scholar] [CrossRef]
- Torales, J.; O’Higgins, M.; Castaldelli-Maia, J.M.; Ventriglio, A. The Outbreak of COVID-19 Coronavirus and Its Impact on Global Mental Health. Int. J. Soc. Psychiatry 2020, 66, 317–320. [Google Scholar] [CrossRef] [Green Version]
- Liu, C.H.; Zhang, E.; Wong, G.T.F.; Hyun, S.; Hahm, H. “Chris” Factors Associated with Depression, Anxiety, and PTSD Symptomatology During the COVID-19 Pandemic: Clinical Implications for U.S. Young Adult Mental Health. Psychiatry Res. Neuroimaging 2020, 290, 113172. [Google Scholar] [CrossRef]
- Sun, L.; Sun, Z.; Wu, L.; Zhu, Z.; Zhang, F.; Shang, Z.; Jia, Y.; Gu, J.; Zhou, Y.; Wang, Y.; et al. Prevalence and Risk Factors of Acute Posttraumatic Stress Symptoms during the COVID-19 Outbreak in Wuhan, China. medRxiv 2020. [Google Scholar] [CrossRef] [Green Version]
- Fekih-Romdhane, F.; Ghrissi, F.; Abbassi, B.; Cherif, W.; Cheour, M. Prevalence and Predictors of PTSD during the COVID-19 Pandemic: Findings From a Tunisian Community Sample. Psychiatry Res. Neuroimaging 2020, 290, 113131. [Google Scholar] [CrossRef] [PubMed]
- Forte, G.; Favieri, F.; Tambelli, R.; Casagrande, M. COVID-19 Pandemic in the Italian Population: Validation of a Post-Traumatic Stress Disorder Questionnaire and Prevalence of PTSD Symptomatology. Int. J. Environ. Res. Public Health 2020, 17, 4151. [Google Scholar] [CrossRef] [PubMed]
- Mowbray, H. In Beijing, Coronavirus 2019-Ncov Has Created a Siege Mentality. BMJ 2020, 368. [Google Scholar] [CrossRef] [Green Version]
- Foppiani, A.; Bertoli, S.; Battezzati, A.; Zuccotti, G.V. Data to Guide the Application of the New WHO Criteria for Releasing COVID-19 Patients from Isolation. Pharmacol. Res. 2020, 105063. [Google Scholar] [CrossRef] [PubMed]
- Chang, M.C.; Hur, J.; Park, D. Interpreting the COVID-19 Test Results. Am. J. Phys. Med. Rehabil. 2020, 99, 583–585. [Google Scholar] [CrossRef]
- Lim, J.; Jeon, S.; Shin, H.-Y.; Kim, M.J.; Seong, Y.M.; Lee, W.J.; Choe, K.-W.; Kang, Y.M.; Lee, B.; Park, S.-J. Case of the Index Patient Who Caused Tertiary Transmission of Coronavirus Disease 2019 in Korea: The Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Pneumonia Monitored by Quantitative RT-PCR. J. Korean Med. Sci. 2020, 35, e79. [Google Scholar] [CrossRef]
- Blevins, C.A.; Weathers, F.W.; Davis, M.T.; Witte, T.; Domino, J.L. The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5): Development and Initial Psychometric Evaluation. J. Trauma. Stress 2015, 28, 489–498. [Google Scholar] [CrossRef]
- Park, H.Y.; Park, W.B.; Lee, S.H.; Kim, J.L.; Lee, J.J.; Lee, H.; Shin, H.-S. Posttraumatic Stress Disorder and Depression of Survivors 12 Months After the Outbreak of Middle East Respiratory Syndrome in South Korea. BMC Public Health 2020, 20, 1–9. [Google Scholar] [CrossRef]
- Hong, X.; Currier, G.W.; Zhao, X.; Jiang, Y.; Zhou, W.; Wei, J. Posttraumatic Stress Disorder in Convalescent Severe Acute Respiratory Syndrome Patients: A 4-Year Follow-up Study. Gen. Hosp. Psychiatry 2009, 31, 546–554. [Google Scholar] [CrossRef]
- Pormohammad, A.; Ghorbani, S.; Khatami, A.; Farzi, R.; Baradaran, B.; Turner, D.L.; Turner, R.J.; Mansournia, M.A.; Kyriacou, D.N.; Bahr, N.C.; et al. Comparison of Confirmed COVID-19 with SARS and MERS Cases—Clinical Characteristics, Laboratory Findings, Radiographic Signs and Outcomes: A Systematic Review and Meta-Analysis. SSRN Electron. J. 2020, 2020, e2112. [Google Scholar] [CrossRef]
- Ettman, C.K.; Abdalla, S.M.; Cohen, G.H.; Sampson, L.; Vivier, P.M.; Galea, S. Prevalence of Depression Symptoms in US Adults Before and During the COVID-19 Pandemic. JAMA Netw. Open 2020, 3, e2019686. [Google Scholar] [CrossRef] [PubMed]
- Krishnamoorthy, Y.; Nagarajan, R.; Saya, G.K.; Menon, V. Prevalence of Psychological Morbidities Among General Population, Healthcare Workers and COVID-19 patients Amidst the COVID-19 Pandemic: A Systematic Review and Meta-Analysis. Psychiatry Res. Neuroimaging 2020, 293, 113382. [Google Scholar] [CrossRef] [PubMed]
- Wang, Y.-X.; Guo, H.-T.; Du, X.-W.; Song, W.; Lu, C.; Hao, W.-N. Factors Associated with Post-Traumatic Stress Disorder of Nurses Exposed to Corona Virus Disease 2019 in China. Medicine 2020, 99, e20965. [Google Scholar] [CrossRef] [PubMed]
PTSD Group | Non-PTSD Group | p-Value | Total | |
---|---|---|---|---|
Number of patients (n) | 13 | 51 | 64 | |
PCL-5 score | 46.0 ± 11.9 | 9.6 ± 7.6 | <0.001 | 17.0 ± 17.1 |
M:F (n) | 4:9 | 24:27 | 0.291 | 28:36 |
Age (years) | 57.8 ± 15.2 | 53.9 ± 17.0 | 0.526 | 54.7 ± 16.6 |
Admission duration (days) | 35.7 ± 21.3 | 30.1 ± 17.2 | 0.499 | 31.2 ± 18.1 |
Duration after discharge (days) | 69.8 ± 25.4 | 77.2 ± 18.4 | 0.457 | 75.7 ± 20.0 |
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Chang, M.C.; Park, D. Incidence of Post-Traumatic Stress Disorder after Coronavirus Disease. Healthcare 2020, 8, 373. https://doi.org/10.3390/healthcare8040373
Chang MC, Park D. Incidence of Post-Traumatic Stress Disorder after Coronavirus Disease. Healthcare. 2020; 8(4):373. https://doi.org/10.3390/healthcare8040373
Chicago/Turabian StyleChang, Min Cheol, and Donghwi Park. 2020. "Incidence of Post-Traumatic Stress Disorder after Coronavirus Disease" Healthcare 8, no. 4: 373. https://doi.org/10.3390/healthcare8040373
APA StyleChang, M. C., & Park, D. (2020). Incidence of Post-Traumatic Stress Disorder after Coronavirus Disease. Healthcare, 8(4), 373. https://doi.org/10.3390/healthcare8040373