The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection
Abstract
:1. Introduction
2. Antioxidant and Antinflammatory Properties of n-3 PUFAs
2.1. Mitochondrial Oxidative Stress and n-3 PUFAs
2.2. Nitric Oxide, Endothelial Dysfunction and n-3 PUFAs
2.3. Cell Membranes and Anti-Inflammatory Effects of n-3 PUFAs
2.4. N-3 PUFA-Derived Mediators
3. Vaso-Protective Activities of n-3 PUFAs
3.1. N-3 PUFAs and Atherosclerosis
3.2. The Effect of n-3 PUFAs in Platelet Function
3.3. N-3 PUFAs Index and Coronary Artery Disease (CAD)
4. The Cardio-Protective Response of n-3 PUFAs Supplementation
4.1. The Effects of n-3 PUFAs in Myocardial Ischemia and Reperfusion
4.2. The Potential for n-3 PUFAs Supplementation in Heart Failure
5. Adverse Effects of PUFAs in Cardiovascular Risk Factors
6. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Oppedisano, F.; Macrì, R.; Gliozzi, M.; Musolino, V.; Carresi, C.; Maiuolo, J.; Bosco, F.; Nucera, S.; Caterina Zito, M.; Guarnieri, L.; et al. The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection. Biomedicines 2020, 8, 306. https://doi.org/10.3390/biomedicines8090306
Oppedisano F, Macrì R, Gliozzi M, Musolino V, Carresi C, Maiuolo J, Bosco F, Nucera S, Caterina Zito M, Guarnieri L, et al. The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection. Biomedicines. 2020; 8(9):306. https://doi.org/10.3390/biomedicines8090306
Chicago/Turabian StyleOppedisano, Francesca, Roberta Macrì, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Jessica Maiuolo, Francesca Bosco, Saverio Nucera, Maria Caterina Zito, Lorenza Guarnieri, and et al. 2020. "The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection" Biomedicines 8, no. 9: 306. https://doi.org/10.3390/biomedicines8090306
APA StyleOppedisano, F., Macrì, R., Gliozzi, M., Musolino, V., Carresi, C., Maiuolo, J., Bosco, F., Nucera, S., Caterina Zito, M., Guarnieri, L., Scarano, F., Nicita, C., Coppoletta, A. R., Ruga, S., Scicchitano, M., Mollace, R., Palma, E., & Mollace, V. (2020). The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection. Biomedicines, 8(9), 306. https://doi.org/10.3390/biomedicines8090306