Special Issue on “Extraction and Purification of Bioactive Compounds”
1
School of Pharmaceutical and Materials Engineering, Taizhou University, Taizhou 318000, China
2
Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310058, China
3
Institute of Zhejiang University-Quzhou, 99 Zheda Road, Quzhou 324000, China
*
Author to whom correspondence should be addressed.
Processes 2023, 11(7), 2034; https://doi.org/10.3390/pr11072034
Submission received: 4 July 2023
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Accepted: 6 July 2023
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Published: 7 July 2023
(This article belongs to the Special Issue Extraction and Purification of Bioactive Compounds)
Bioactive compounds, which are abundant in flora, fauna, and microorganisms, can potentially be used by various industries, including pharmaceuticals, functional foods, dietary supplements, and cosmetics. Their extraction and purification, however, pose significant challenges due to the presence of impurities, interference from other compounds, and the need to maintain their stability and activity. This Special Issue, “Extraction and Purification of Bioactive Compounds” (https://www.mdpi.com/journal/processes/special_issues/extraction_bioactive accessed on 4 July 2023), delves into the complexities of these processes, presenting one review paper and eleven original research articles that explore the enrichment, identification, and various aspects of bioactive compounds.
The issue begins with the extraction of bioactive compounds from living organisms. Corrêa et al. [1] provide a comprehensive review of the current methodologies used for obtaining bioactive products from microalgae, discussing technologies used for cell disruption, selective extraction, recovery, and purification. Ghafoor et al. [2] compare conventional and green extraction techniques for natural antioxidants from Saudi date fruit, optimizing the supercritical extraction process using a response surface methodology and regression analysis techniques. A team from Serbia [3] explores the carotenoid extraction protocol using yeast fermentation technology, testing various methods for cell lysis, extraction, and solvents.
Additionally, the utilization of resins for the adsorption of bioactive compounds is addressed. Wu et al. [4] discuss the ion exchange strategy with Dowex® HCR-S resin for the isolation and purification of ectoine, a high-value bioactive compound, from a fermentation broth. Zain et al. [5] examine three macroporous resins for the enrichment of four bioactive compounds from an acid-hydrolyzed oil palm leaves extract, selecting the best-performing resin based on its sorption capacities.
The identification of bioactive compounds is another key focus of this issue. Chu et al. [6] extract phenolic compounds from ten common commercial mushroom species, identifying different phenolic compounds using LC-ESI-QTOF-MS/MS. Cao et al. [7] analyze the constituents of acidic compounds in the particulate and gaseous phases of mainstream cigarette smoke. Other researchers investigate the composition of bioactive compounds in organically produced cereals [8], dried sea cucumber viscera [9], and the medicinal plant, Clinacanthus nutans [10].
The issue concludes with an overview of the other aspects of bioactive compounds. Ramakrishnan et al. [11] optimize the operation parameters of enzymatic transesterification for biodiesel production from salmon oil. Xu et al. [12] measure the solubility of the high-value biocompound, 2,5-furandicarboxylic acid (FDCA), and its synthetic intermediate in binary solvent mixtures of water and 1,4-dioxane.
This Special Issue comprehensively explores the extraction and purification of bioactive compounds, shedding light on the complexities of these processes and the potential these compounds hold for various industries. We hope that the insights will inspire future research and innovation in this exciting field.
Author Contributions
Conceptualization, writing—review and editing, writing—original draft preparation, methodology, formal analysis, resources, investigation, data curation, Q.X.; validation, supervision, project administration, funding acquisition, Z.B. All authors have read and agreed to the published version of the manuscript.
Conflicts of Interest
The authors declare no conflict of interest.
References
- Corrêa, P.S.; Morais Júnior, W.G.; Martins, A.A.; Caetano, N.S.; Mata, T.M. Microalgae Biomolecules: Extraction, Separation and Purification Methods. Processes 2021, 9, 10. [Google Scholar] [CrossRef]
- Ghafoor, K.; Sarker, M.Z.I.; Al-Juhaimi, F.Y.; Babiker, E.E.; Alkaltham, M.S.; Almubarak, A.K.; Ahmed, I.A.M. Innovative and Green Extraction Techniques for the Optimal Recovery of Phytochemicals from Saudi Date Fruit Flesh. Processes 2022, 10, 2224. [Google Scholar] [CrossRef]
- Šovljanski, O.; Saveljić, A.; Tomić, A.; Šeregelj, V.; Lončar, B.; Cvetković, D.; Ranitović, A.; Pezo, L.; Ćetković, G.; Markov, S.; et al. Carotenoid-Producing Yeasts: Selection of the Best-Performing Strain and the Total Carotenoid Extraction Procedure. Processes 2022, 10, 1699. [Google Scholar] [CrossRef]
- Wu, Y.-C.; Wei, Y.-H.; Wu, H.-S. Adsorption and Desorption Behavior of Ectoine Using Dowex® HCR-S Ion-Exchange Resin. Processes 2021, 9, 2068. [Google Scholar] [CrossRef]
- Che Zain, M.S.; Lee, S.Y.; Teo, C.Y.; Shaari, K. Adsorption/Desorption Characteristics and Simultaneous Enrichment of Orientin, Isoorientin, Vitexin and Isovitexin from Hydrolyzed Oil Palm Leaf Extract Using Macroporous Resins. Processes 2021, 9, 659. [Google Scholar] [CrossRef]
- Chu, M.; Khan, R.D.; Zhou, Y.; Agar, O.T.; Barrow, C.J.; Dunshea, F.R.; Suleria, H.A.R. LC-ESI-QTOF-MS/MS Characterization of Phenolic Compounds in Common Commercial Mushrooms and Their Potential Antioxidant Activities. Processes 2023, 11, 1711. [Google Scholar] [CrossRef]
- Lu, X.; Zhang, H.; Cao, Y.; Pang, Y.; Zhou, G.; Huang, H.; Li, J.; Jiang, J.; Yang, Q. A Comprehensive Study on the Acidic Compounds in Gas and Particle Phases of Mainstream Cigarette Smoke. Processes 2023, 11, 1694. [Google Scholar] [CrossRef]
- Hussain, A.; Larsson, H.; Johansson, E. Carotenoid Extraction from Locally and Organically Produced Cereals Using Saponification Method. Processes 2021, 9, 783. [Google Scholar] [CrossRef]
- Liu, Y.; Dave, D.; Trenholm, S.; Ramakrishnan, V.V.; Murphy, W. Effect of Drying on Nutritional Composition of Atlantic Sea Cucumber (Cucumaria frondosa) Viscera Derived from Newfoundland Fisheries. Processes 2021, 9, 703. [Google Scholar] [CrossRef]
- Cheng, A.Y.F.; Teoh, P.L.; Jayasinghe, L.; Cheong, B.E. Volatile Profiling Aided in the Isolation of Anti-Proliferative Lupeol from the Roots of Clinacanthus nutans (Burm. f.) Lindau. Processes 2021, 9, 1383. [Google Scholar] [CrossRef]
- Ramakrishnan, V.V.; Dave, D.; Liu, Y.; Routray, W.; Murphy, W. Statistical Optimization of Biodiesel Production from Salmon Oil via Enzymatic Transesterification: Investigation of the Effects of Various Operational Parameters. Processes 2021, 9, 700. [Google Scholar] [CrossRef]
- Xu, L.; Fu, J.; Du, C.; Xu, Q.; Liu, B.; Bao, Z. Solubility of Biocompounds 2,5-Furandicarboxylic Acid and 5-Formylfuran-2-Carboxylic Acid in Binary Solvent Mixtures of Water and 1,4-Dioxane. Processes 2022, 10, 2480. [Google Scholar] [CrossRef]
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MDPI and ACS Style
Xu, Q.; Bao, Z. Special Issue on “Extraction and Purification of Bioactive Compounds”. Processes 2023, 11, 2034. https://doi.org/10.3390/pr11072034
AMA Style
Xu Q, Bao Z. Special Issue on “Extraction and Purification of Bioactive Compounds”. Processes. 2023; 11(7):2034. https://doi.org/10.3390/pr11072034
Chicago/Turabian StyleXu, Qianqian, and Zongbi Bao. 2023. "Special Issue on “Extraction and Purification of Bioactive Compounds”" Processes 11, no. 7: 2034. https://doi.org/10.3390/pr11072034
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