1. Introduction
The permeation of atoms, molecules, and nanoparticles through a dense liquid, membrane or polymer network is a complex problem characterized by many factors at the nanometric scale and is important in materials science, nanotechnology, and polymer physics [
1,
2,
3,
4]. Among potential applications, the following can be mentioned: the separation of gases and organic molecules in rubbery and glassy polymeric media [
4,
5,
6], barrier materials for coatings [
7], solvent transport in biological and polymeric materials [
8], nanofiltration [
9], and drug release [
10]. The permeation coefficient is given by the multiple of the penetrant solubility at equilibrium and the diffusion coefficient. This latter transport property is generally sensitive to many thermodynamic factors.
Determining the diffusion coefficient is of great importance in many operations involving the processing and use of polymeric materials; however, obtaining its experimental value can be challenging due to numerous technical aspects. These difficulties often require the estimation of diffusion coefficients based on mathematical models. The literature presents various models that have been developed, starting from several concepts.
Penetrant diffusion coefficient values are often built on the free volume concept [
11,
12], which controls molecular transport. This concept, first introduced by Cohen and Turnbull in 1959 [
13], is well known in polymer science. The derivation is based on the idea that diffusive displacement is due to voids generated by the redistribution of free volume. The diffusion constant
D in a liquid of hard spheres and the “free volume”
νf is as follows:
The free volume space is actually the corresponding volume occupied by the molecules and their surrounding space. The random thermal fluctuations of the fluid lead to the continuous redistribution of the free volume. Contrary to the free volume, the occupied volume is independent of temperature. A molecule migrates in the liquid when a free volume hole occurs near the molecule. Therefore, random fluctuation in the local density results in molecular diffusion. According to the Cohen—Turnbull theory, the self-diffusion coefficient in a pure liquid depends on the probability that a hole of critical size is formed due to random fluctuations in free volume [
14].
The Fujita model [
15] is the first one based on the free volume theory. For its development, a system composed of one solvent, one plasticizer, and one polymer was experimentally investigated. In relation to the polymer concentration, a low value of plasticizer concentration was maintained so that the considered ternary system could be reduced to a pseudo-binary one. Consequently, the mean free volume was caused by the solvent and the polymer. Further, Fujita estimated the free volume based on Cohen and Turnbull’s concept. Thus, assuming a liquid composed of identical molecules, the probability of finding voids of size
ν* can be expressed as follows:
Fujita assumed that Equation (2) is also valid for binary systems. The probability that a molecule finds a void is closely related to the mobility of the diffuser,
md:
The definition of mobility is given by the Equation (4):
Substituting Equation (3) in (4) results in expression (5):
Although the Fujita model can be used for the theoretical description of diffusion in polymer–organic solvent systems, in polymer–water systems, it does not provide reliable results due to the numerous interactions between molecules.
Following the Fujita model, Yasuda et al. [
16] assumed that the free volume of a binary system depends mainly on the solvent volume fraction. This hypothesis stands on the assumption that the solvent mobility is significantly higher than that of a polymer. Thus, the effective free volume is mainly caused by the solvent, and the solvent diffusion decreases with polymer concentration. Therefore, the total free volume is due to both the solvent and the polymer, and is expressed by Equation (6):
Assuming no interactions between a molecule and polymer, it can be written as follows:
The model of Yasuda et al. can be used for diffusion studies in dilute or semi-dilute polymer systems, and for diffusing molecules of relatively small size.
This free volume concept has been extended by Vrentas and Duda (1977) [
11] for the case of concentrated polymer solutions. Later, Vrentas et al. (1984) [
17] applied this model to describe diffusion in ternary polymer–solvent–solvent systems using binary polymer–solvent diffusion data.
According to the model, polymer volume is divided into three elements (
Figure 1). (a) The occupied volume corresponds to the polymer volume with no free volume, and is also known as the “van der Waals” volume. It has a constant value, independent of temperature, and can be estimated based on non-bonded contact radii and bond distances. (b) The interstitial free volume originates from the vibrational energy of polymer chains, and it is slightly dependent on temperature. (c) The hole free volume stems from volume relaxation and plasticization due to polymer heating and cooling, and can be affected by solvent adsorption/desorption. The total polymer volume is mainly influenced by the hole free volume. Fast polymer relaxations allow rubbery polymers to achieve the equilibrium volume. Glassy polymers, however, are nonequilibrium liquids where relaxation is slow. Therefore, as more hole free volume is confined, glassy polymers present a larger volume than at equilibrium.
Although polymers may be considered porous in this context, Duda and Zielinski [
18] emphasized that the volume confined in glassy polymers is repeatedly distributed. In cases of porous materials, the solvent governs the transport mechanism. Commonly, numerous polymers are nonporous. In this instance, the solvent within the polymer remains undefined, and the transport mechanism cannot be addressed in terms of liquid or vapor.
In the literature, the diffusion coefficient in polymer–solvent systems is called the “self-diffusion coefficient” as well. According to the IUPAC, when the chemical potential gradient is zero, the diffusion coefficient of species i is referred to as the self-diffusion coefficient [
19]. Accurately, according to Albright and Milles, this nomenclature is valid in cases of one component diffusion within itself [
20].
In terms of the types of diffusion coefficients, the literature mentions self-diffusion coefficients, reciprocal diffusion coefficients, mutual diffusion coefficients, Fick diffusion coefficients, etc. [
21,
22,
23].
In order to describe the diffusion phenomenon in polymers, Vrentas and Duda [
11] developed the free volume theory. The mutual diffusion coefficient is the product of a solvent self-diffusion coefficient and a thermodynamic factor:
For ternary polymer–solvent 1–solvent 2 systems, the self diffusion coefficient is given as follows:
where
D0i is the pre-exponential factor of component
i;
ωi represents the weight fraction; and
is the specific critical hole free volume necessary for a jump of component
i. The total hole free volume,
, is a function of parameters
KI,i and
KII,i − Tgi. The parameters
D0 and
ξ are very sensitive. By strongly varying these two parameters, specific dependences of the diffusion coefficient can be described.
Although diffusion and mass transport coefficients can be determined through relatively simple experiments, following the mass variation over time, the particular case of polymer–solvent systems is highly complex. Diffusion in these systems is influenced by numerous factors. Consequently, the literature reports plenty of experimental data and computational models. We consider that many aspects still remain unexplained, and research in this field is ongoing.
The experimental data obtained through a gravitational technique allow the highlighting of the diffusion mechanism and the selection of an appropriate mathematical model. A change in the structure of the polymer during the experiment leads to diffusion anomalies. Three different polymer–solvent systems are considered, CA-THF, PVA-H2O, and CTA-DCM, in order to calculate diffusion coefficients at various compositions and temperatures. Mathematical models can be useful in studies regarding the drying of polymer films with complex structures, providing knowledge for designing or selecting suitable equipment.
2. Diffusion Coefficients from Experimental Data
2.1. Methodology
The experimental determination of the diffusion coefficients in polymeric membranes/films involves conducting experiments in which the polymeric films/membranes are brought into contact with the component whose diffusion coefficient is to be determined. The values of the diffusion coefficients depend on the diffusion type, which is influenced by the nature of the used polymer (the type of polymer) and the diffusion temperature, which influences the amorphous or crystalline state of the polymer. It is also very well known that the glass transition temperature, Tg, takes different values during diffusion and depends on the polymer purity. A change in concentration can lead to important changes in Tg. As a result, in the diffusion experimental test, the change in the concentration of the polymer membrane/film must take place over the narrowest possible range. The range of concentration variation can be controlled by establishing equilibrium conditions between the fluid phase and the polymer membrane/film within which the diffusion of a certain component takes place.
Diffusion experiments mostly monitor either the variation of the mass of the polymer film over time or the variation of the amount of diffusing component over time.
The first step in the processing of experimental data is the graphical plot of the diffusing component mass as a function of the diffusion time. The shape of this simple dependence can provide the first insights into the diffusion mechanism. Subsequently, the experimental data are processed using literature models that account for various factors such as different operating conditions, diverse behaviors of the system during diffusion, the type of polymer used, structural transformations occurring in the membrane/film during diffusion, and the type of membrane interaction with the diffusing component, among others.
Figure 2 presents a scheme of the proposed methodology.
Diffusion processes in one dimension are expressed as follows:
where
D is the mutual diffusion coefficient and
C is the concentration. Having the initial and boundary conditions corresponding to a 2
l (−
l to
l) thickness of a film exposed to an infinite reservoir [
24]:
Crank [
24] reported the solution of Equation (14) based on the boundary conditions (15):
Equation (16) [
24] can be further derived for the specific case of gravimetric sorption:
where
Mt and
Meq are the amount of penetrant diffused into the polymer at a given time,
t, and the penetrate amount at equilibrium, respectively.
In a particular case of short time, Equation (17) becomes the following:
and can be further approximated as follows:
The diffusion coefficient can be determined by means of Equation (20), determining the initial slope,
S, of the dependence
Mt/
Meq and
:
When diffusion occurs in films/membranes with different thicknesses, a more accurate dependence is
Mt/
Meq to
. The determined initial slope,
Sl, of the dependence is as follows:
where
is the following:
where
is the slope of the first part of sorption curve during the initial time period. As shown in Equations (18)–(20), the diffusion coefficient depends on both the film thickness and the initial slope of the linear part of the absorption curve. This provides information on the rate of absorption of the solvent vapor mass on the polymer membrane.
When diffusion of penetrant in polymer reveals a non-Fickian behavior, the approach of diffusion coefficient estimation on the basis of the initial stage and constant diffusion coefficient is widely accepted by the scientific community [
25,
26,
27,
28,
29,
30].
2.2. Fick or Non-Fick Diffusion
Polymers in a solid state can reach two different states. At values below the glass transition temperature, the polymer is in crystalline state, a hard and brittle material. The glass transition temperature is the temperature at which a polymer changes from a crystalline to an amorphous state [
31]. The concept of glassy state was presented in detail by Arya et al. [
32].
Most of the properties, such as diffusivity, thermal conductivity, specific volume, dielectric constant, refractive index, and hardness, vary considerably for polymers in amorphous and crystalline states, respectively. The difference between the polymer physical properties in amorphous and crystalline states is caused by the mobility of the macromolecular chain.
Theories and models describing diffusion in polymers rely on chain mobility at the molecular scale. When a polymer absorbs a solvent, its molecules rearrange until a new equilibrium conformation is established. In an amorphous state, the diffusion follows a Fick-type mechanism. In this case, the polymer chain segments are active enough to reach structural equilibrium instantaneously.
In crystalline polymers, the equilibrium chain conformation establishes much slower due to the limited mobility of the polymer segments. In this particular case, different types of segmental motion generate different diffusion mechanisms under various conditions.
Diffusion mechanisms in crystalline polymers can be classified as [
31] (1) case I (Fickian) diffusion, and (2) case II (non-Fickian) diffusion, anomalous diffusion.
Sorption kinetics are shown by the concentration distribution of the penetrant in the polymer or by the change in polymer weight due to absorption. Differential or interval sorption occurs when the difference between the activity of the external penetrant and that of the equilibrium penetrant in the polymer has a very low value. This results in small variations in the penetrant concentration in the polymer. This kind of kinetics allows one to calculate values of diffusion coefficients throughout a narrow range of concentrations, and the obtained data highlight the variation of diffusion coefficient as a function of concentration. Even though the method (Quartz Crystal Balance, NMR, IGC, etc.) used is different, the literature presents diffusion coefficients obtained from sorption–desorption experiments.
Case II is particular to sorption processes of small molecules in crystalline polymers or during the interdiffusion of polymers when only one polymer is in a crystalline state [
33,
34].
Characteristic of case II sorption are the following key features: (i) the necessity of an induction time for the formation of the fluid penetration front; (ii) the consistent movement of the front at a constant velocity; (iii) the inverse relationship between the induction time and the front penetration rate; and (iv) the nearly stepwise distribution of penetrant concentration within the swelling polymer.
The following observations are also associated with case II sorption: (i) the fronts serve as a distinct indication of the heterogeneity within the swelling polymer; (ii) the rate controlling process occurs at the front; (iii) case II sorption is nonlinear and irreversible; and (iv) case II sorption may be treated as a quasi-steady transport process.
When a glassy polymer interacts with a highly active organic swelling agent, it undergoes partial absorption almost instantaneously, filling the vacant free volume at its surface. Subsequent absorption of the diffusant induces swelling or the plasticization of the polymer. This transformation in the polymer’s state is facilitated by alterations in its conformation, affecting its chains or segments. The dynamics of this conformational change are dictated by the mobility of the polymer chain, which is influenced by both intramolecular and intermolecular forces. These forces, in turn, can be manipulated by factors such as experimental temperature, diffusant type, and concentration. The resulting conformational changes, crucial for concentration kinetics, do not occur instantaneously, requiring a significant time interval for the diffusant’s surface concentration to reach equilibrium.
The heterogeneous nature of the swelling polymer can be segmented into three distinct regions: a swollen zone, a transitional swelling area, and an unswollen region. Isotropic conformational shifts in polymer chains due to penetrant swelling lead to lateral expansion parallel to the polymer’s surface. However, this expansion is constrained by the unswollen core through neighboring unaffected chains and segments. The most energetically favorable path for this conformational change lies perpendicular to the surface. Consequently, changes in polymer conformation and sample dimension are anisotropic. The swelling region manifests as an interface or front separating the swollen zone from the unswollen region. Nevertheless, this demarcation is not strictly geometric. In the case of poly(methyl methacrylate) (PMMA)/methanol systems, the estimated thickness of the swelling region is approximately 100 nm, as established by Durning et al. [
34].
Polymer relaxation in response to osmotic swelling stresses or plasticization primarily occurs within this region. The kinetics of relaxation and plasticization are contingent upon the diffusant’s activity within this region and the morphology of the unswollen polymer proximate to it. Within the swollen region, osmotic swelling pressure combines with differential swelling stress, typically compressive in nature. In instances where the swollen region is homogeneous, diffusion can be elucidated using a modified form of Fick’s law, incorporating stress and concentration-dependent diffusion coefficients. Depending on experimental conditions, the swollen polymer may exhibit either a rubbery or glassy state. Notably, DSC results on PMMA-methanol systems have revealed instances where the swollen PMMA remains in a glassy state at temperatures below 313 K, as shown by Lin et al. [
35].
The unswollen glassy region’s homogeneity or heterogeneity is contingent upon the level of tensile stress and plasticization engendered by the diffusant. Heterogeneity arises when the stress exceeds the yield strength of the unswollen polymer, potentially resulting in cracking. Diffusion in this region may follow Fickian or non-Fickian behavior, contingent upon the morphology and degree of mechanical damage present within the unswollen core. Mechanical damage or core failure due to differential swelling stresses may accelerate the migration of the swelling region when diffusional resistance is minimal. Consequently, a spectrum of diffusion patterns may manifest within the same polymer across varying temperatures, diffusant types, and activities.
The diffusion process is strongly influenced by several parameters (including temperature, pressure, solute size, and the viscosity of the medium in which the diffusion occurs). Consequently, diffusion processes in liquids and solids are much slower. Diffusion coefficients are difficult to estimate with theoretical models, since in solids, they can differ by one or more orders of magnitude. Guiding values of the diffusion coefficients in the three states of aggregation are given in
Figure 3.
3. Materials and Methods
The experimental data used to derive the diffusion coefficients were obtained in two ways: (i) for the drying of polyvinyl alcohol (PVA)–distilled water and cellulose acetate (CA)-tetrahydrofurane (THF, anhydrous, ≥99.9%, Sigma Aldrich, Saint Louis, MO, USA) films; and (ii) in cases of sorption/desorption of dichloromethane (DMT, anhydrous, ≥99.8%, Sigma Aldrich, Saint Louis, MO, USA) in cellulose triacetate (CTA, Sigma Aldrich, Saint Louis, MO, USA) films using the sorption equipment with magnetic suspension coupling, described in our prior work [
26].
The experiments were carried out at 303 and 323 K using cellulose triacetate–dichloromethane films. Solvent concentration was modified according to the solvent activity in a sorption cell. Each experiment was carried out in the presence of a pure dichloromethane vapor (in absence of air) at a fixed temperature in a sorption cell connected to an evaporator. Solvent activity in the sorption cell was adjusted by controlling the temperature in the evaporator. The polymer films were obtained by the slow evaporation of the solvent from a cellulose triacetate-dichloromethane solution. Film thickness was determined according to film weight, film surface, and polymer density [
36].
PVA is a synthetic, linear, non-toxic semi-crystalline polymer, biocompatible, biodegradable, and water soluble at temperatures above its glass transition (85 °C). The PVA-H2O film was prepared by adding a 5% solution of PVA (powder, average Mw 89,000–98,000, Sigma Aldrich, Saint Louis, MO, USA) in distilled water.
Cellulose acetate (CA) is an important cellulose ester described by Fischer et al. [
37]. CA powder (average M
w~30,000) was purchased from Sigma Aldrich (Saint Louis, MO, USA).
For the CTA-DCM system, the experimental method and procedures are described in our prior work [
38].
The solvents selected in these tests, to solubilize the considered polymers, were THF, DCM, and distilled water, respectively.
The equipment used for the PVA-H
2O system is presented in work [
26]. The drying equipment was an in-house set-up and included a drying tunnel with a rectangular section. The weighing of the samples was performed with a digital analytical balance (Precisa Gravimetrics AG, Dietikon, Switzerland) with a 0.1 mg sensitivity. Absolute pressure was measured using a Tecsis pressure gauge (WIKA Group, Kent, UK) connected do a data logger, midi Logger GL800 (Graphtec Corporation, Shenzhen, China). Temperature measurements were carried out using thermocouples (Pt 100) connected to a data logger (Sper Scientific, Scottsdale, AZ, USA 800024 Thermocouple Thermometer, 4 Channel Datalogging).
5. Conclusions
The practical aspects regarding diffusion in polymer films are of great importance in managing the drying processes of polymer films. The use for large-scale energy conversion of materials that include polymer layers of small thicknesses (e.g., photovoltaic cells) is well known.
This study makes a unique contribution by demonstrating how diffusion coefficients can be established based on experimental data from different applications. The manuscript explores several cases concerning solvent diffusion in polymers and demonstrates effective methods for extracting diffusion coefficients from experimental data obtained from two different experimental setups: one involving a drying tunnel for PVA in water and CA in THF films, and the other consisting of sorption equipment with magnetic suspension coupling for the sorption/desorption of DCM in CTA films. For the CTA-DCM system, the diffusion coefficient at 303 K varies between 4.5 and 8·10−11 m2 s−1 at different concentrations. For the PVA-H2O system, the diffusion coefficient is 4.1·10−12 m2 s−1 at 303 K and 6.5·10−12 m2 s−1 at 333 K. Meanwhile, for the CA-THF system, the solvent–polymer diffusion coefficient is 2.5·10−12 m2 s−1 at 303 K and 1.75·10−11 m2 s−1at 323 K.
The obtained data from drying experiments can be correlated using mathematical models that represent various types of behavior in polymer systems. These models offer valuable insights for designing specialized equipment or for scaling-up processes.
Mathematical models for penetrant diffusion in glassy or amorphous polymer films were used to determine diffusion coefficients in polymer films on the basis of experimental data.
The simulation results have demonstrated that the state of polymer has an important influence on the concentration profiles vs. time. Mathematical equations that describe diffusion in polymers under different conditions were used to simulate the drying of polymer films. Data on film thickness, average diffusion coefficient and time were used for the simulations.
The obtained results show that, based on some imposed parameters, the drying time periods can be estimated, which then allows the selection or design of specific apparatus.