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Article
Peer-Review Record

Effect of Genistein on Starch Digestion In Vitro and Its Mechanism of Action

Foods 2024, 13(17), 2809; https://doi.org/10.3390/foods13172809
by Jianhui Jia, Boxin Dou, Man Gao, Chujia Zhang, Ying Liu * and Na Zhang
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Foods 2024, 13(17), 2809; https://doi.org/10.3390/foods13172809
Submission received: 22 July 2024 / Revised: 30 August 2024 / Accepted: 2 September 2024 / Published: 4 September 2024
(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

1. The abstract is too long. 

2. The introduction should be improved. Literature concerning genistein sources and content (ranges of concentrations) must be complemented and presented in detail. Ln 60: "plant-derived - not clear - please elaborate this and support with additional literature.

3. L99-100 purity and composition must be provided. One batch sample was used? Starch must be characterized in detail.

4. Ln 107-122: Is this method described elsewhere? Why such conditions and enzyme activities were applied?

5. Ln 129-132: The method is not referenced. Do you mean the glucose oxidase method? What is the influence of genistein on glucose oxidase???

6. Why exactly acarbose was selected as a positive control?

7. The discussion should be extended - inhibition of amylases by other similar compounds (acarbose, other) should be presented, compared to the genistein. The result of the comparison to other amylase-inhibiting substances should be presented in conclusions to evaluate the potential of genistein.

8. list of references is double numbered.

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

All detailed comments are noted in the manuscripts' pdf file

Comments for author File: Comments.pdf

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

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