This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Open AccessArticle
Evaluation of Prebiotic and Health-Promoting Functions of Honeybee Brood Biopeptides and Their Maillard Reaction Conjugates
by
Sakaewan Ounjaijean
Sakaewan Ounjaijean 1
,
Supakit Chaipoot
Supakit Chaipoot 2,3
,
Rewat Phongphisutthinant
Rewat Phongphisutthinant 2,3
,
Gochakorn Kanthakat
Gochakorn Kanthakat 4
,
Sirinya Taya
Sirinya Taya 2,
Pattavara Pathomrungsiyounggul
Pattavara Pathomrungsiyounggul 4
,
Pairote Wiriyacharee
Pairote Wiriyacharee 2,3,5
and
Kongsak Boonyapranai
Kongsak Boonyapranai 1,*
1
Research Institute for Health Sciences, Chiang Mai University, Chiang Mai 50200, Thailand
2
Multidisciplinary Research Institute, Chiang Mai University, Chiang Mai 50200, Thailand
3
Research Center of Microbial Diversity and Sustainable Utilization, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand
4
Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand
5
Processing and Product Development Factory, The Royal Project Foundation, Chiang Mai 50100, Thailand
*
Author to whom correspondence should be addressed.
Foods 2024, 13(17), 2847; https://doi.org/10.3390/foods13172847 (registering DOI)
Submission received: 29 July 2024
/
Revised: 2 September 2024
/
Accepted: 6 September 2024
/
Published: 7 September 2024
Abstract
This study addresses the growing interest in natural functional ingredients by evaluating the prebiotic and health-promoting functions of honeybee brood biopeptides (HBb-Bps) and their conjugates. The purpose was to investigate their antioxidant activities, enzyme inhibition properties, and effects on probiotic growth and short-chain fatty acid (SCFA) production. The HBb-Bps were conjugated with honey, glucose, and fructose via the Maillard reaction. Antioxidant activities were assessed using DPPH and ABTS assays. The inhibitory effects on amylase, pancreatic lipase, and the angiotensin-converting enzyme (ACE) were measured. Probiotic growth and SCFA production were evaluated using L. plantarum TISTR846, and L. lactis TISTR1464. The HBb-Bps and their conjugates exhibited enhanced antioxidant activities post-Maillard reaction. They showed moderate enzyme inhibition, which decreased after conjugation. However, ACE inhibition increased with conjugation. The HBb-Bps significantly promoted probiotic growth and SCFA production, with further enhancement by the Maillard reaction. Overall, the HBb-Bps and their conjugates demonstrate significant prebiotic and health-promoting functions, suggesting their potential as natural ingredients in functional foods and nutraceuticals. Further research should focus on the in vivo effects and, given their solubility and stability these biopeptides could be incorporated into functional food formulations, such as health beverages, protein bars, and other fortified foods designed to deliver specific health benefits.
Share and Cite
MDPI and ACS Style
Ounjaijean, S.; Chaipoot, S.; Phongphisutthinant, R.; Kanthakat, G.; Taya, S.; Pathomrungsiyounggul, P.; Wiriyacharee, P.; Boonyapranai, K.
Evaluation of Prebiotic and Health-Promoting Functions of Honeybee Brood Biopeptides and Their Maillard Reaction Conjugates. Foods 2024, 13, 2847.
https://doi.org/10.3390/foods13172847
AMA Style
Ounjaijean S, Chaipoot S, Phongphisutthinant R, Kanthakat G, Taya S, Pathomrungsiyounggul P, Wiriyacharee P, Boonyapranai K.
Evaluation of Prebiotic and Health-Promoting Functions of Honeybee Brood Biopeptides and Their Maillard Reaction Conjugates. Foods. 2024; 13(17):2847.
https://doi.org/10.3390/foods13172847
Chicago/Turabian Style
Ounjaijean, Sakaewan, Supakit Chaipoot, Rewat Phongphisutthinant, Gochakorn Kanthakat, Sirinya Taya, Pattavara Pathomrungsiyounggul, Pairote Wiriyacharee, and Kongsak Boonyapranai.
2024. "Evaluation of Prebiotic and Health-Promoting Functions of Honeybee Brood Biopeptides and Their Maillard Reaction Conjugates" Foods 13, no. 17: 2847.
https://doi.org/10.3390/foods13172847
Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details
here.
Article Metrics
Article Access Statistics
For more information on the journal statistics, click
here.
Multiple requests from the same IP address are counted as one view.