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Toxics, Volume 10, Issue 8

August 2022 - 80 articles

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Cover Story: Humans are exposed to many environmental chemicals and their mixtures. There is increasing scientific information describing their relationships with numerous adverse health effects. Therefore, artificial intelligence and the development of biological databases could be used to systematically explore the toxicological and epidemiological data available in the scientific literature, e.g., through the bioinformatics tool AOP-helpFinder, which allows for the construction of adverse outcome pathways (AOPs), and the identification of associations between these environmental stressors and human health, thus supporting chemical risk assessment. AOP-helpFinder has been successfully applied to explore the relationships between PFAS exposure and metabolic health outcomes. View this paper

Articles (80)

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,706 Views
12 Pages
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Intrauterine and Extrauterine Environmental PM2.5 Exposure Is Associated with Overweight/Obesity (O/O) in Children Aged 6 to 59 Months from Lima, Peru: A Case-Control Study

  • Valeria M. Paz-Aparicio,
  • Vilma Tapia,
  • Bertha Vanessa Vasquez-Apestegui,
  • Kyle Steenland and
  • Gustavo F. Gonzales
Toxics2022, 10(8), 487;https://doi.org/10.3390/toxics10080487

22 August 2022

There is evidence that PM2.5 could be obesogenic. Lima is one of the most polluted cities in South America, with an increasing prevalence of childhood obesity. This study aimed to determine the association between PM2.5 exposure of children aged 6 to...

Full Article
  • Case Report
  • Open Access
6 Citations
6,345 Views
10 Pages
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Forensic Aspects of a Fatal Intoxication Involving Acetaminophen, Citalopram and Trazodone: A Case Report

  • Giulio Mannocchi,
  • Roberta Tittarelli,
  • Flaminia Pantano,
  • Francesca Vernich,
  • Margherita Pallocci,
  • Pierluigi Passalacqua,
  • Michele Treglia and
  • Luigi Tonino Marsella
Toxics2022, 10(8), 486;https://doi.org/10.3390/toxics10080486

22 August 2022

We report the case of a young man, a former heroin addict, found dead at home by the Police Forces in an advanced state of decomposition. Numerous blisters and unpacked tablets of medications were found all over the bed and on the floor of the room....

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  • Article
  • Open Access
5 Citations
2,086 Views
12 Pages
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Insights into the Seasonal Olfactory Mechanism of Geosmin in Raw Water of Huangpu River

  • Fei Luo,
  • Hui Chen,
  • Xiaoxin Wu,
  • Lili Liu,
  • Yuean Chen and
  • Zhiping Wang
Toxics2022, 10(8), 485;https://doi.org/10.3390/toxics10080485

19 August 2022

Since the 1990s, the raw water of Huangpu River in Shanghai, China, has intermittently encountered off-flavor contamination. In this work, the concentrations of typical odor, geosmin, in raw water of Huangpu River are found to shift along with the se...

Full Article
  • Review
  • Open Access
418 Citations
34,757 Views
24 Pages
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Recent Strategies for Bioremediation of Emerging Pollutants: A Review for a Green and Sustainable Environment

  • Saroj Bala,
  • Diksha Garg,
  • Banjagere Veerabhadrappa Thirumalesh,
  • Minaxi Sharma,
  • Kandi Sridhar,
  • Baskaran Stephen Inbaraj and
  • Manikant Tripathi
Toxics2022, 10(8), 484;https://doi.org/10.3390/toxics10080484

19 August 2022

Environmental pollution brought on by xenobiotics and other related recalcitrant compounds have recently been identified as a major risk to both human health and the natural environment. Due to their toxicity and non-biodegradability, a wide range of...

Full Article
  • Article
  • Open Access
15 Citations
3,514 Views
26 Pages
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HBM4EU Chromates Study—Genotoxicity and Oxidative Stress Biomarkers in Workers Exposed to Hexavalent Chromium

  • Ana Tavares,
  • Kukka Aimonen,
  • Sophie Ndaw,
  • Aleksandra Fučić,
  • Julia Catalán,
  • Radu Corneliu Duca,
  • Lode Godderis,
  • Bruno C. Gomes,
  • Beata Janasik and
  • Carina Ladeira
  • + 12 authors
Toxics2022, 10(8), 483;https://doi.org/10.3390/toxics10080483

18 August 2022

A study was conducted within the European Human Biomonitoring Initiative (HBM4EU) to characterize occupational exposure to Cr(VI). Herein we present the results of biomarkers of genotoxicity and oxidative stress, including micronucleus analysis in ly...

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  • Article
  • Open Access
10 Citations
3,392 Views
14 Pages
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Efficiency of Several Cytochrome P450 Biomarkers in Highlighting the Exposure of Daphnia magna to an Organophosphate Pesticide

  • Elodie Melo de Almeida,
  • Floriane Tisserand,
  • Micaela Faria and
  • Nathalie Chèvre
Toxics2022, 10(8), 482;https://doi.org/10.3390/toxics10080482

17 August 2022

The cytochromes P450 (CYP450) represent a major enzyme family operating mostly in the first step of xenobiotic detoxification in aquatic organisms. The ability to measure these CYP450 enzymes’ activities provides a crucial tool to understand or...

Full Article
  • Article
  • Open Access
9 Citations
2,912 Views
24 Pages
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Time Trends of Acrylamide Exposure in Europe: Combined Analysis of Published Reports and Current HBM4EU Studies

  • Michael Poteser,
  • Federica Laguzzi,
  • Thomas Schettgen,
  • Nina Vogel,
  • Till Weber,
  • Philipp Zimmermann,
  • Domenica Hahn,
  • Marike Kolossa-Gehring,
  • Sónia Namorado and
  • An Van Nieuwenhuyse
  • + 19 authors
Toxics2022, 10(8), 481;https://doi.org/10.3390/toxics10080481

17 August 2022

More than 20 years ago, acrylamide was added to the list of potential carcinogens found in many common dietary products and tobacco smoke. Consequently, human biomonitoring studies investigating exposure to acrylamide in the form of adducts in blood...

Full Article
  • Review
  • Open Access
22 Citations
5,191 Views
30 Pages
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The Use of Human Biomonitoring to Assess Occupational Exposure to PAHs in Europe: A Comprehensive Review

  • Henriqueta Louro,
  • Bruno Costa Gomes,
  • Anne Thoustrup Saber,
  • Anna Laura Iamiceli,
  • Thomas Göen,
  • Kate Jones,
  • Andromachi Katsonouri,
  • Christiana M. Neophytou,
  • Ulla Vogel and
  • Célia Ventura
  • + 7 authors
Toxics2022, 10(8), 480;https://doi.org/10.3390/toxics10080480

17 August 2022

Polycyclic aromatic hydrocarbons (PAHs) are among the chemicals with proven impact on workers’ health. The use of human biomonitoring (HBM) to assess occupational exposure to PAHs has become more common in recent years, but the data generated n...

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  • Article
  • Open Access
45 Citations
7,015 Views
15 Pages
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Ecotoxicity of Polyvinylidene Difluoride (PVDF) and Polylactic Acid (PLA) Microplastics in Marine Zooplankton

  • Michela Di Giannantonio,
  • Chiara Gambardella,
  • Roberta Miroglio,
  • Elisa Costa,
  • Francesca Sbrana,
  • Marco Smerieri,
  • Giovanni Carraro,
  • Roberto Utzeri,
  • Marco Faimali and
  • Francesca Garaventa
Toxics2022, 10(8), 479;https://doi.org/10.3390/toxics10080479

17 August 2022

The aim of this study was to investigate the ecotoxicity of polyvinylidene difluoride (PVDF) and polylactic acid (PLA) microplastics (MPs) in two marine zooplankton: the crustacean Artemia franciscana and the cnidarian Aurelia sp. (common jellyfish)....

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  • Article
  • Open Access
14 Citations
3,326 Views
18 Pages
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Physico-Chemical and Ecotoxicological Evaluation of Marine Sediments Contamination: A Case Study of Rovinj Coastal Area, NE Adriatic Sea, Croatia

  • Jadranka Pelikan,
  • Nina Majnarić,
  • Maja Maurić Maljković,
  • Kristina Pikelj and
  • Bojan Hamer
Toxics2022, 10(8), 478;https://doi.org/10.3390/toxics10080478

16 August 2022

Comprehensive spatial and temporal data on sediment quality in the Adriatic Sea are lacking. Therefore, prior to planned anthropogenic interventions in the local marine environment, such as deepening of the Rovinj harbour, the results of physicochemi...

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