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Medicines, Volume 10, Issue 3

2023 March - 6 articles

Cover Story: Lack of reliable information hinders evaluation of suspected herb–drug interactions. This survey-based study analyzes real-life experiences with herb–drug interaction from the perspective of healthcare providers and laypersons. Interactions were evaluated against resources cited for the evaluation of potential supplement–drug interactions. Disproportionality analyses were performed using the FAERS, CFSAN, and CAERS databases. Secondary aims included exploring reasons for respondent use of dietary supplements and qualitative analysis of respondent’s perceptions of dietary supplement–drug interaction. While agreement among reported supplement–drug interactions with commonly cited resources via disproportionality analyses through FAERS was low, agreement using CAERS was high. View this paper

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Review

2,534 Views

8 Pages

Therapeutic Potential of Two Derivative Prescriptions of Rokumijiogan, Hachimijiogan and Bakumijiogan against Renal Damage in Nephrectomized Rats

Chan Hum Park,
Takashi Tanaka,
Yoshie Akimoto,
Jin Pyeong Jeon and
Takako Yokozawa

Medicines2023, 10(3), 24;https://doi.org/10.3390/medicines10030024

21 March 2023

Background: Hachimijiogan (HJG) and Bakumijiogan (BJG), two derivative prescriptions of Rokumijiogan (RJG), were selected to investigate their renoprotective potential in the 5/6 nephrectomized (5/6Nx) rat model. Methods: Rats were treated with HJG a...

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Article

1 Citations

3,135 Views

7 Pages

Health Technology Assessment of Different Glucosamine Formulations and Preparations Currently Marketed in Thailand

Olivier Bruyère,
Johann Detilleux and
Jean-Yves Reginster

Medicines2023, 10(3), 23;https://doi.org/10.3390/medicines10030023

8 March 2023

Objective: The aim of this study was to evaluate the cost-effectiveness of different glucosamine formulations and preparations used for the management of osteoarthritis in Thailand compared with placebo. Methods: We used a validated model to simulate...

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Brief Report

2,312 Views

11 Pages

Evaluation of Nutritional Status in an Acute Geriatric Unit: Retrospective Study and Analysis of Frailty Syndrome

Abrar-Ahmad Zulfiqar,
Ibrahima Amadou Dembele and
Emmanuel Andres

Medicines2023, 10(3), 22;https://doi.org/10.3390/medicines10030022

8 March 2023

Introduction: The aim of our study is to evaluate the nutritional status of patients in an acute geriatric unit. Methods: Patients included in the study were hospitalized in an acute geriatric unit over a period of 6 months. The nutritional status of...

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Brief Report

1 Citations

3,969 Views

8 Pages

Effect of Dexamethasone on Abiraterone Pharmacokinetics in Mice: Determined by LC/MS Analysis

Subrata Deb,
Mohamed Ben-Eltriki,
Hans Adomat,
Mei Y. Chin and
Emma S. Tomlinson Guns

Medicines2023, 10(3), 21;https://doi.org/10.3390/medicines10030021

6 March 2023

Background: Abiraterone acetate is a cytochrome P450 17A1 (CYP17A1) inhibitor that is indicated for use in both castration-resistant and castration-sensitive prostate cancer patients. To manage the mineralocorticoid effects of CYP17A1 inhibition, a g...

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Article

7 Citations

6,375 Views

16 Pages

Everyday Evaluation of Herb/Dietary Supplement–Drug Interaction: A Pilot Study

Joao Victor Souza-Peres,
Kimberly Flores,
Bethany Umloff,
Michelle Heinan,
Paul Herscu and
Mary Beth Babos

Medicines2023, 10(3), 20;https://doi.org/10.3390/medicines10030020

28 February 2023

A lack of reliable information hinders the clinician evaluation of suspected herb–drug interactions. This pilot study was a survey-based study conceived as a descriptive analysis of real-life experiences with herb–drug interaction from th...

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Article

15 Citations

11,159 Views

19 Pages

Clinical Benefit of Autologous Platelet-Rich Plasma Infusion in Ovarian Function Rejuvenation: Evidence from a Before-After Prospective Pilot Study

Athanasios Garavelas,
Panagiotis Mallis,
Efstathios Michalopoulos and
Eros Nikitos

Medicines2023, 10(3), 19;https://doi.org/10.3390/medicines10030019

27 February 2023

Background: The intraovarian administration of autologous platelet-rich plasma (PRP) acts beneficially for the stimulation of follicle production in women presenting different forms of ovarian dysfunction. This pilot study aimed to evaluate and provi...

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