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Review

Health-Promoting Effects of Bioactive Compounds from Plant Endophytic Fungi

1
Department of Food Science and Technology, University of Peradeniya, Peradeniya 20400, Sri Lanka
2
Food Science and Technology Program, Department of Life Sciences, BNU-HKBU United International College, Zhuhai 519087, China
*
Author to whom correspondence should be addressed.
J. Fungi 2023, 9(10), 997; https://doi.org/10.3390/jof9100997
Submission received: 28 August 2023 / Revised: 3 October 2023 / Accepted: 7 October 2023 / Published: 8 October 2023
(This article belongs to the Special Issue Diversity and Molecular Systematics of Plant Endophytic Fungi)

Abstract

The study examines the intricate relationship between plants and the endophytic fungi inhabiting their tissues. These fungi harmoniously coexist with plants, forming a distinct symbiotic connection that has caught scientific attention due to its potential implications for plant health and growth. The diverse range of bioactive compounds produced by these fungi holds significant promise for human health. The review covers various aspects of this topic, starting by introducing endophytic microorganisms, explaining their colonization of different plant parts, and illuminating their potential roles in enhancing plant defense against diseases and promoting growth. The review emphasizes the widespread occurrence and diversity of these microorganisms among plant species while highlighting the complexities and significance of isolating and extracting bioactive compounds from them. It focuses on the health benefits of these bioactive compounds, including their capacity to exhibit antioxidant, anti-inflammatory, antimicrobial, and anticancer effects. The review delves into the mechanisms behind these health-promoting effects, spotlighting how the compounds interact with cellular receptors, signaling pathways, and gene expression. In conclusion, the review provides a comprehensive overview of health-promoting bioactive compounds from plant endophytic fungi. It outlines their multifaceted impact, potential applications, and future research avenues in health and medicine.
Keywords: plant endophytic fungi; bioactive compounds; human health; mechanism of action; pharmaceuticals plant endophytic fungi; bioactive compounds; human health; mechanism of action; pharmaceuticals

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MDPI and ACS Style

Wijesekara, T.; Xu, B. Health-Promoting Effects of Bioactive Compounds from Plant Endophytic Fungi. J. Fungi 2023, 9, 997. https://doi.org/10.3390/jof9100997

AMA Style

Wijesekara T, Xu B. Health-Promoting Effects of Bioactive Compounds from Plant Endophytic Fungi. Journal of Fungi. 2023; 9(10):997. https://doi.org/10.3390/jof9100997

Chicago/Turabian Style

Wijesekara, Tharuka, and Baojun Xu. 2023. "Health-Promoting Effects of Bioactive Compounds from Plant Endophytic Fungi" Journal of Fungi 9, no. 10: 997. https://doi.org/10.3390/jof9100997

APA Style

Wijesekara, T., & Xu, B. (2023). Health-Promoting Effects of Bioactive Compounds from Plant Endophytic Fungi. Journal of Fungi, 9(10), 997. https://doi.org/10.3390/jof9100997

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