Hydrogel-Transformable Antioxidant Poly-γ-Glutamic Acid/Polyethyleneimine Hemostatic Powder for Efficient Wound Hemostasis
Abstract
:1. Introduction
2. Results and Discussion
2.1. Preparation and Characterization of the PP Hemostatic Powder
2.2. Mechanical and Rheological Properties
2.3. Swelling and Degradation
2.4. Antioxidant Properties
2.5. In Vitro Safety
2.6. In Vitro Hemostasis Experiments
2.7. In Vivo Hemostasis Experiments
3. Conclusions
4. Materials and Methods
4.1. Materials
4.2. Preparation of the PP Hemostatic Powder
4.3. Characterization
4.4. Mechanical Testing
4.5. Study of Swelling Behaviors
4.6. In Vitro Degradation
4.7. Antioxidant Properties
4.7.1. ABTS· Scavenging Experiment
4.7.2. DPPH· Scavenging Experiment
4.7.3. PTIO· Scavenging Experiment
4.8. Blood Compatibility
4.9. In Vitro Hemostasis Test
4.10. In Vivo Hemostasis Study
4.11. Statistical Analysis
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Li, X.; Han, W.; He, G.; Yang, J.; Li, J.; Ma, H.; Wang, S. Hydrogel-Transformable Antioxidant Poly-γ-Glutamic Acid/Polyethyleneimine Hemostatic Powder for Efficient Wound Hemostasis. Gels 2024, 10, 68. https://doi.org/10.3390/gels10010068
Li X, Han W, He G, Yang J, Li J, Ma H, Wang S. Hydrogel-Transformable Antioxidant Poly-γ-Glutamic Acid/Polyethyleneimine Hemostatic Powder for Efficient Wound Hemostasis. Gels. 2024; 10(1):68. https://doi.org/10.3390/gels10010068
Chicago/Turabian StyleLi, Xiang, Wenli Han, Gao He, Jiahao Yang, Jing Li, Hongxia Ma, and Shige Wang. 2024. "Hydrogel-Transformable Antioxidant Poly-γ-Glutamic Acid/Polyethyleneimine Hemostatic Powder for Efficient Wound Hemostasis" Gels 10, no. 1: 68. https://doi.org/10.3390/gels10010068