Based on the Co-Evolution of lncRNAs-Microbiota and Metabolites in Rumen Epithelium to Analyze the Adaptation Characteristics of Tibetan Sheep to Nutrient Stress in the Cold Season
, Xinyu Guo 1, Yuzhu Sha 1, Yanyu He 2, Pengyang Shao 1, Jiang Hu 1, Jiqing Wang 1, Shaobin Li 1 and Zhiyun Hao 1
Round 1
Reviewer 1 Report
Mention the latitude and longitude of the location where the experiment was conducted.
The aim of the study is not clear in the abstract.
Are 12 animals enough to conduct this study?
I would like to correct some of the tenses used in the manuscript, such as in line 39, it is written “is” instead of “was.”
Author Response
Mention the latitude and longitude of the location where the experiment was conducted.
Reply: Thank the reviewers for their valuable suggestions. In the material method, we provide the latitude and longitude information of the response.
The aim of the study is not clear in the abstract.
Reply: Thank you for your question. In the abstract part, we have modified and clarified the research goal.
Are 12 animals enough to conduct this study?
Reply: The 12 Tibetan sheep selected in this study were from the same herder's flock, and 12 were randomly selected as research objects, and ear-tagged for tracking and measurement, which can also represent the group in a grazing area. In addition, for the study of the number of groups, the number of this study may be a little small, due to the original design of the experiment, we have a great limit in the number of samples. However, the question raised by the reviewer is of great help to our subsequent research, and more consideration should be given to whether the sample size can represent the population.
I would like to correct some of the tenses used in the manuscript, such as in line 39, it is written “is” instead of “was.”
Reply: Thanks for the questions raised by the reviewers, we have checked the grammar of the whole paper and made modifications. And it was checked by native English-speaking professionals.
Reviewer 2 Report
In my opinion, appropriate and at the same time focused research of a strictly scientific nature.
Author Response
In my opinion, appropriate and at the same time focused research of a strictly scientific nature.
Reply: We would like to thank the reviewers for their review of our research and their recognition of our research content. In addition, according to the comments of editors and other reviewers, we further modified and improved the manuscript, hoping to further improve the quality of our article.
