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Case Report

Long-Term Remission after Erlotinib Therapy in an Elderly Patient with Advanced Non-small Cell Lung Cancer. Case Report and Conclusions for Clinical Practice

by
Renata Duchnowska
1,*,
Anna Siemiątkowska
2,
Bartłomiej Grala
3 and
Marta Smoter
1
1
Department of Oncology, Military Institute of Medicine in Warsaw, 128 Szaserów St., 00-909 Warsaw, Poland
2
Department of Biology and Genetics, Medical University of Gdańsk, 80-210 Gdańsk, Poland
3
Department of Pathology, Military Institute of Medicine in Warsaw, 128 Szaserów St., 00-909 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2008, 76(6), 451-455; https://doi.org/10.5603/ARM.27862
Submission received: 10 March 2008 / Revised: 31 October 2008 / Accepted: 31 October 2008 / Published: 31 October 2008

Abstract

Small molecule tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR)—gefitinib and erlotinib—have recently been used as a therapeutic option in advanced non-small cell lung cancer (NSCLC) patients relapsing after first- or second-line chemotherapy. We report here a case of long-term remission in an elderly, non-smoking woman with advanced NSCLC after chemotherapy failure, who was selected for erlotinib therapy using demographic and clinical criteria. Based on this example and on the literature data we discuss the need for careful patient selection for this new therapeutic method.
Keywords: non-small cell lung cancer; erlotinib; targeted therapies non-small cell lung cancer; erlotinib; targeted therapies

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MDPI and ACS Style

Duchnowska, R.; Siemiątkowska, A.; Grala, B.; Smoter, M. Long-Term Remission after Erlotinib Therapy in an Elderly Patient with Advanced Non-small Cell Lung Cancer. Case Report and Conclusions for Clinical Practice. Adv. Respir. Med. 2008, 76, 451-455. https://doi.org/10.5603/ARM.27862

AMA Style

Duchnowska R, Siemiątkowska A, Grala B, Smoter M. Long-Term Remission after Erlotinib Therapy in an Elderly Patient with Advanced Non-small Cell Lung Cancer. Case Report and Conclusions for Clinical Practice. Advances in Respiratory Medicine. 2008; 76(6):451-455. https://doi.org/10.5603/ARM.27862

Chicago/Turabian Style

Duchnowska, Renata, Anna Siemiątkowska, Bartłomiej Grala, and Marta Smoter. 2008. "Long-Term Remission after Erlotinib Therapy in an Elderly Patient with Advanced Non-small Cell Lung Cancer. Case Report and Conclusions for Clinical Practice" Advances in Respiratory Medicine 76, no. 6: 451-455. https://doi.org/10.5603/ARM.27862

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