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  • Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
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18 July 2020

Transbronchial Lung Cryobiopsy (TBCB) Performed in Acute COVID-19 Pneumonia: First Report

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,
and
1
Pulmonary and Critical Care Medicine Department, Loewenstein Lung Center, Löwenstein, Baden-Wurttemberg, Germany
2
Department of Pulmonary Medicine, Mansoura Univeristy, Mansoura, Egypt
3
Pathology Department, SLK Klinik Heilbronn, Heilbronn, Germany
*
Author to whom correspondence should be addressed.
Adv. Respir. Med.2021, 89(1), 72-74;https://doi.org/10.5603/ARM.a2021.0032
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Abstract

A COVID-19 diagnosis is usually based on PCR detection of viral RNA in airway specimens in a patient with typical clinical fea-tures. Histological features of the COVID-19 lung disease are reported from autopsies. Transbronchial cryobiopsy (TBCB) is an evolving technique usually performed in the diagnosis of interstitial lung disease. We report a TBCB in a 76-year-old female patient who had repeatedly tested negative for SARS-CoV-2 infection. The pathological examination revealed the presence of interstitial pneumonia with lymphocytic infiltration. The qRT-PCR against SARS-CoV-2 from a pharyngeal swab was positive after performing the TBCB.

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