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Case Report

Transbronchial Lung Cryobiopsy (TBCB) Performed in Acute COVID-19 Pneumonia: First Report

by
Ahmed Ehab
1,2,*,
Florian Reissfelder
3,
Juergen Laufer
3 and
Axel Tobias Kempa
1
1
Pulmonary and Critical Care Medicine Department, Loewenstein Lung Center, Löwenstein, Baden-Wurttemberg, Germany
2
Department of Pulmonary Medicine, Mansoura Univeristy, Mansoura, Egypt
3
Pathology Department, SLK Klinik Heilbronn, Heilbronn, Germany
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2021, 89(1), 72-74; https://doi.org/10.5603/ARM.a2021.0032
Submission received: 18 July 2020 / Revised: 28 February 2021 / Accepted: 28 February 2021 / Published: 18 July 2020

Abstract

A COVID-19 diagnosis is usually based on PCR detection of viral RNA in airway specimens in a patient with typical clinical fea-tures. Histological features of the COVID-19 lung disease are reported from autopsies. Transbronchial cryobiopsy (TBCB) is an evolving technique usually performed in the diagnosis of interstitial lung disease. We report a TBCB in a 76-year-old female patient who had repeatedly tested negative for SARS-CoV-2 infection. The pathological examination revealed the presence of interstitial pneumonia with lymphocytic infiltration. The qRT-PCR against SARS-CoV-2 from a pharyngeal swab was positive after performing the TBCB.
Keywords: COVID-19; pneumonia; transbronchial lung cryobiopsy COVID-19; pneumonia; transbronchial lung cryobiopsy

Share and Cite

MDPI and ACS Style

Ehab, A.; Reissfelder, F.; Laufer, J.; Kempa, A.T. Transbronchial Lung Cryobiopsy (TBCB) Performed in Acute COVID-19 Pneumonia: First Report. Adv. Respir. Med. 2021, 89, 72-74. https://doi.org/10.5603/ARM.a2021.0032

AMA Style

Ehab A, Reissfelder F, Laufer J, Kempa AT. Transbronchial Lung Cryobiopsy (TBCB) Performed in Acute COVID-19 Pneumonia: First Report. Advances in Respiratory Medicine. 2021; 89(1):72-74. https://doi.org/10.5603/ARM.a2021.0032

Chicago/Turabian Style

Ehab, Ahmed, Florian Reissfelder, Juergen Laufer, and Axel Tobias Kempa. 2021. "Transbronchial Lung Cryobiopsy (TBCB) Performed in Acute COVID-19 Pneumonia: First Report" Advances in Respiratory Medicine 89, no. 1: 72-74. https://doi.org/10.5603/ARM.a2021.0032

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