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Transplantology, Volume 4, Issue 1

2023 March - 5 articles

Cover Story: When a partial liver graft is transplanted into a recipient with portal hypertension, it is subject to sinusoidal shear stress, which, in good measure, is essential for regeneration. However, portal hyperperfusion which exceeds the capacity of the graft results in the small-for-size syndrome manifested by ascites, cholestasis and coagulopathy. This review discusses intraoperative hemodynamic variables that have been described in the literature, as well as inflow modulation strategies and their outcomes. Apart from using donor grafts which are of adequate size for the recipient weight, portal hemodynamics are an important consideration to prevent early allograft dysfunction, graft failure and mortality. View this paper
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Articles (5)

  • Article
  • Open Access
3 Citations
3,069 Views
16 Pages
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Comparison of Benefits and Risks Associated with Anti-T-Lymphocyte Globulin (ATLG) Serotherapy in Methotrexate (MTX)- versus Mycophenolate Mofetil (MMF)-Based Hematopoietic Stem Cell Transplantation

  • Alexander Nikoloudis,
  • Irene Strassl,
  • Michaela Binder,
  • Olga Stiefel,
  • Dagmar Wipplinger,
  • Robert Milanov,
  • Christoph Aichinger,
  • Emine Kaynak,
  • Sigrid Machherndl-Spandl and
  • Johannes Clausen
  • + 6 authors
Transplantology2023, 4(1), 22-37;https://doi.org/10.3390/transplantology4010005

17 February 2023

Background: Serotherapy with anti-T lymphocyte globulin (ATLG, Grafalon, formerly ATG-Fresenius) is established for the prevention of severe graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). The evidence from pros...

Full Article
  • Case Report
  • Open Access
2,766 Views
5 Pages
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Successful Utilization of Kidney Allografts with Diffuse Glomerular Fibrin Thrombi on the Preimplantation Biopsy after Circulatory Death: A Case Series

  • Sushma Bhusal,
  • Hailey Hardgrave,
  • Aparna Sharma,
  • Lyle Burdine,
  • Raj Patel,
  • Gary Barone,
  • Neriman Gokden and
  • Emmanouil Giorgakis
Transplantology2023, 4(1), 12-16;https://doi.org/10.3390/transplantology4010002

12 January 2023

Background: Kidney allografts with the presence of diffuse glomerular fibrin thrombi are typically rejected by most centers due to concern for poor allograft outcomes in the recipients. The aim of this study was to report our single center experience...

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  • Article
  • Open Access
2 Citations
4,789 Views
11 Pages
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The Non-Muscle-Splitting Mini-Incision Donor Nephrectomy Remains a Feasible Technique in the Laparoscopic Era of Living Kidney Donation

  • Lex J. M. Habets,
  • Andrzej G. Baranski,
  • Khalil Ramdhani,
  • Danny van der Helm,
  • Ada Haasnoot,
  • Aiko P. J. de Vries,
  • Koen E. A. van der Bogt,
  • Andries E. Braat,
  • Jeroen Dubbeld and
  • Volkert A. L. Huurman
  • + 6 authors
Transplantology2023, 4(1), 1-11;https://doi.org/10.3390/transplantology4010001

27 December 2022

Laparoscopic donor nephrectomy (LDN) is the current gold standard in kidney donation. Mini-incision open donor nephrectomy (MINI) techniques have been used extensively but have become less popular. The aim of the present study was to compare the resu...

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