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BioMedInformatics, Volume 2, Issue 3

2022 September - 11 articles

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Articles (11)

  • Review
  • Open Access
5 Citations
6,111 Views
17 Pages

Background: The application of machine learning (ML) tools (MLTs) to support clinical trials outputs in evidence-based health informatics can be an effective, useful, feasible, and acceptable way to advance medical research and provide precision medi...

  • Article
  • Open Access
20 Citations
5,309 Views
19 Pages

Interpretable Machine Learning with Brain Image and Survival Data

  • Matthias Eder,
  • Emanuel Moser,
  • Andreas Holzinger,
  • Claire Jean-Quartier and
  • Fleur Jeanquartier

Recent developments in research on artificial intelligence (AI) in medicine deal with the analysis of image data such as Magnetic Resonance Imaging (MRI) scans to support the of decision-making of medical personnel. For this purpose, machine learning...

  • Article
  • Open Access
2 Citations
3,828 Views
18 Pages

Despite the great progress in its early diagnosis and treatment, colon adenocarcinoma (COAD) is still poses important issues to clinical management. Therefore, the identification of novel biomarkers or therapeutic targets for this disease is importan...

  • Article
  • Open Access
3 Citations
3,258 Views
15 Pages

Background: Pulmonary hypertension (PH) is a complex disease caused by a wide range of underlying conditions, Tanshinone IIA (Tan IIA) has been widely used in PH patients. The study aimed to explore the possible molecular mechanism of Tan IIA against...

  • Review
  • Open Access
145 Citations
47,373 Views
25 Pages

The lack of consistent presentation of results in published studies on the association between a quantitative explanatory variable and a quantitative dependent variable has been a long-term issue in evaluating the reported findings. Studies are analy...

  • Article
  • Open Access
2 Citations
3,612 Views
10 Pages

Background: Endoplasmic reticulum stress (ERS) is involved in the etiology of non-alcoholic fatty liver disease (NAFLD). Thus, the current study was designed to identify key ERS-associated genes in NAFLD. Methods: RNA-Seq data of NAFLD and controls w...

  • Article
  • Open Access
19 Citations
21,649 Views
19 Pages

Aedes Larva Detection Using Ensemble Learning to Prevent Dengue Endemic

  • Md Shakhawat Hossain,
  • Md Ezaz Raihan,
  • Md Sakir Hossain,
  • M. M. Mahbubul Syeed,
  • Harunur Rashid and
  • Md Shaheed Reza

Dengue endemicity has become regular in recent times across the world. The numbers of cases and deaths have been alarmingly increasing over the years. In addition to this, there are no direct medications or vaccines to treat this viral infection. Thu...

  • Brief Report
  • Open Access
10 Citations
2,376 Views
7 Pages

A New Epidemic Model for the COVID-19 Pandemic: The θ-SI(R)D Model

  • Ettore Rocchi,
  • Sara Peluso,
  • Davide Sisti and
  • Margherita Carletti

Since the beginning of the COVID-19 pandemic, a large number of epidemiological models have been developed. The principal objective of the present study is to provide a new six-compartment model for the COVID-19 pandemic, which takes into account bot...

  • Article
  • Open Access
3 Citations
3,994 Views
23 Pages

A Systems Biology- and Machine Learning-Based Study to Unravel Potential Therapeutic Mechanisms of Midostaurin as a Multitarget Therapy on FLT3-Mutated AML

  • Marina Díaz-Beyá,
  • María García-Fortes,
  • Raquel Valls,
  • Laura Artigas,
  • Mª Teresa Gómez-Casares,
  • Pau Montesinos,
  • Fermín Sánchez-Guijo,
  • Mireia Coma,
  • Meritxell Vendranes and
  • Joaquín Martínez-López

Acute myeloid leukemia (AML), a hematologic malignancy that results in bone marrow failure, is the most common acute leukemia in adults. The presence of FMS-related tyrosine kinase 3 (FLT3) mutations is associated with a poor prognosis, making the ev...

  • Article
  • Open Access
5 Citations
3,279 Views
16 Pages

In the context of improving clinical treatments and certifying clinics, guideline-compliant care has become more important. However, verifying the compliance of treatment procedures with Clinical Guidelines remains difficult, as guidelines are mostly...

  • Article
  • Open Access
64 Citations
8,691 Views
14 Pages

An LDA–SVM Machine Learning Model for Breast Cancer Classification

  • Onyinyechi Jessica Egwom,
  • Mohammed Hassan,
  • Jesse Jeremiah Tanimu,
  • Mohammed Hamada and
  • Oko Michael Ogar

Breast cancer is a prevalent disease that affects mostly women, and early diagnosis will expedite the treatment of this ailment. Recently, machine learning (ML) techniques have been employed in biomedical and informatics to help fight breast cancer....

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BioMedInformatics - ISSN 2673-7426