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International Journal of Translational Medicine, Volume 1, Issue 1

June 2021 - 6 articles

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Articles (6)

  • Article
  • Open Access
4,291 Views
14 Pages

HGF and VEGF-A and Their Receptors Show Expression and Angiogenic Effects on Human Choroidal Endothelial Cells: Implications for Treatments of Neovascular Age-Related Macular Degeneration

  • Elizabeth A. Stewart,
  • Claire L. Allen,
  • Govindi J. Samaranayake,
  • Thomas Stubington,
  • Rukhsar Akhtar,
  • Matthew J. Branch and
  • Winfried M. Amoaku

Intraocular neovascularisation is associated with common blinding conditions including neovascular age-related macular degeneration (nAMD). Vascular endothelial growth factor (VEGF) is central in driving choroidal neovascularisation in this disease....

  • Review
  • Open Access
7 Citations
5,953 Views
14 Pages

Circulating tumor cells (CTCs) are gaining momentum as a diagnostic tool and therapeutic target. CTC clusters are more metastatic, but harder to study and characterize, because they are rare and the methods of isolation are mostly focused on single C...

  • Review
  • Open Access
4 Citations
5,769 Views
16 Pages

The Contribution of Endothelial-Mesenchymal Transition to Atherosclerosis

  • Jinyu Zhang,
  • Stella C. Ogbu,
  • Phillip R. Musich,
  • Douglas P. Thewke,
  • Zhiqiang Yao and
  • Yong Jiang

Atherosclerosis is a chronic progressive condition in which the wall of the artery develops abnormalities and causes thickening of the blood vessels. The development of atherosclerosis is a complex process characterized by vascular inflammation and t...

  • Article
  • Open Access
2 Citations
4,432 Views
14 Pages

Retinal diseases are the leading causes of irreversible blindness worldwide. The role of toll-like receptor (TLR) signalling mechanisms (MyD88 and TRIF) in the production of pro-angiogenic growth factors from human microvascular endothelial cells (HM...

  • Review
  • Open Access
1 Citations
5,030 Views
21 Pages

Development of Multilayer Mesenchymal Stem Cell Cell Sheets

  • Jun Ochiai,
  • Yutaka Niihara and
  • Joan Oliva

Cell and gene therapies have been developing dramatically over the past decade. To face and adapt to the development of these new therapies, the Food and Drug Administration (FDA) wrote and updated new guidelines from 2016 and keep updating them. Mes...

  • Feature Paper
  • Editorial
  • Open Access
2,797 Views
3 Pages

The International Journal of Translational Medicine (ISSN 2673-8937) is an open access journal that lays its foundation in a diverse editorial board that takes advantage from the distinctive expertise of the various members [...]

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Int. J. Transl. Med. - ISSN 2673-8937Creative Common CC BY license