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Oxygen, Volume 4, Issue 4 (December 2024) – 1 article

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14 pages, 969 KiB  
Review
The Role of ROS in Electronic Cigarette- and Heated Tobacco Product-Induced Damage
by Nancy E. Gomez and Silvia Granata
Oxygen 2024, 4(4), 363-376; https://doi.org/10.3390/oxygen4040022 - 25 Sep 2024
Viewed by 523
Abstract
The success of heated tobacco products (HTPs) and electronic cigarettes (e-cigs) has been largely attributed to their ability to mimic the gestural experience of traditional cigarette smoking, while being perceived as a safer alternative due to the absence of combustion, as well as [...] Read more.
The success of heated tobacco products (HTPs) and electronic cigarettes (e-cigs) has been largely attributed to their ability to mimic the gestural experience of traditional cigarette smoking, while being perceived as a safer alternative due to the absence of combustion, as well as to their appeal, particularly among younger populations. Despite the initial idea that these new devices were harmless, recent literature reveals a concerning expanding body of evidence on their potential toxicity. Thus, this literature review aims to elucidate the mechanisms by which reactive oxygen species generated by HTPs and e-cigs induce oxidative stress and inflammation and the subsequent biological and health consequences, in order to raise awareness on the significance of addressing the potential toxicological effects associated with these devices, which are commonly believed to be safe. Full article
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