Advanced Research on Machine Learning Algorithms in Bioinformatics

Dear colleagues,

Epigenetic variation and, more generally, somatic mutations represent molecular components of biodiversity that directly link the genome to the environment. Recently, epigenetics emerged as a promising aspect for the diagnosis of several disorders. It could become an opportunity to uncover new mechanisms as well as therapeutic targets for cancer and analyze their links with metabolic dysregulation. The application of machine learning and automated reasoning techniques to mutational studies composed of huge amounts of multi-omics data could significantly boost discovery and therapy development. For these reasons, we invite you to submit your latest research related to the development and application of artificial intelligence methods to this kind of problem to this Special Issue. It will focus on algorithms in the following areas:

• Epigenomic and multi-omics data clustering;
• Computational approaches to modeling and optimizing cancer treatment;
• Patient-specific integrated network modeling;
• Single-cell analysis in cancer genomics and epigenomics;
• Modeling the evolutionary dynamics of cancer: from epigenetic regulation to cell population dynamics.

Prof. Dr. Carla Piazza
Guest Editor

Dr. Roberto Pagliarini
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Algorithms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• artificial intelligence
• computational biology
• machine learning
• genomics
• data clustering