From Anatomy to Clinical Neurosciences

A special issue of Anatomia (ISSN 2813-0545).

Deadline for manuscript submissions: 31 January 2025 | Viewed by 930

Special Issue Editor


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Guest Editor
1. Department of Medical Education, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA
2. Department of Neurosciences, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA
Interests: neurobiology; vestivular neurosciences; inner ear evolution

Special Issue Information

Dear Colleagues,

Anatomical sciences is an umbrella that encompass anatomy, neuroscience, histology and cell biology, and embryology. Furthermore, anthrobiology as a discipline is tightly related to anatomy, since it entails morphometric studies of the human body. The close relationship of the subdisciplines of anatomy may hold true in a pedagogical sense; however, these different disciplines are highly divergent. Even within one of anatomy, such as neuroscience, there are several research topics and interests, such as neural devlopment, functional neurosciences, and neuroimaging. The current Special Issue aims to determine areas of commonality between these different emergent reasearch interests.

Dr. Adel Maklad
Guest Editor

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Keywords

  • gross anatomy
  • functional anatomy
  • microscopic anatomy
  • developmental neurosciences
  • functional neuroanatomy
  • sensory systems
  • developmental biology
  • pedagogical anatomy

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Published Papers (1 paper)

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Research

8 pages, 793 KiB  
Communication
Effects of Congenital Adrenal Hyperplasia (CAH) and Biological Sex on Brain Size
by Eileen Luders, Christian Gaser, Debra Spencer, Ajay Thankamony, Ieuan Hughes, Umasuthan Srirangalingam, Helena Gleeson, Melissa Hines and Florian Kurth
Anatomia 2024, 3(3), 155-162; https://doi.org/10.3390/anatomia3030012 - 18 Jul 2024
Viewed by 602
Abstract
Congenital Adrenal Hyperplasia (CAH) has been reported to involve structural alterations in some brain regions. However, it remains to be established whether there is also an impact on the size of the brain as a whole. Here, we compiled the largest CAH sample [...] Read more.
Congenital Adrenal Hyperplasia (CAH) has been reported to involve structural alterations in some brain regions. However, it remains to be established whether there is also an impact on the size of the brain as a whole. Here, we compiled the largest CAH sample to date (n = 53), matched pair-wise to a control group (n = 53) on sex, age, and verbal intelligence. Using T1-weighted brain scans, we calculated intracranial volume (ICV) as well as total brain volume (TBV), which are both common estimates for brain size. The statistical analysis was performed using a general linear model assessing the effects of CAH (CAH vs. controls), sex (women vs. men), and any CAH-by-sex interaction. The outcomes were comparable for ICV and TBV, i.e., there was no significant main effect of CAH and no significant CAH-by-sex interaction. However, there was a significant main effect of sex, with larger ICVs and TBVs in men than in women. Our findings contribute to an understudied field of research exploring brain anatomy in CAH. In contrast to some existing studies suggesting a smaller brain size in CAH, we did not observe such an effect. In other words, ICV and TBV in women and men with CAH did not differ significantly from those in controls. Notwithstanding, we observed the well-known sex difference in brain size (12.69% for ICV and 12.50% for TBV), with larger volumes in men than in women, which is in agreement with the existing literature. Full article
(This article belongs to the Special Issue From Anatomy to Clinical Neurosciences)
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